20 results about "Oil ingredients" patented technology

The invention discloses an antiviral preparation and a preparation method thereof, and relates to the field of pharmaceutical preparations, the process is innovated, traditional Chinese medicinal materials with antiviral volatile oil as a main effective component are subjected to a supercritical CO2 extraction technology, high-purity antiviral volatile oil can be extracted at a low temperature, the problem that the antiviral volatile oil is unstable at a high temperature is avoided, and the antiviral volatile oil can be used for preparing the antiviral preparation. Meanwhile, specific steps of granulation, oil loading and closed braising are matched, an ethanol solvent is used as a medium, wetting is firstly carried out, soft material granulation is prepared, a hydrophilic particle skeleton is constructed, then dissolving is carried out, antiviral volatile oil is sprayed and attached to particles, and after closed braising, the anti-virus composition is obtained. The dispersion degree and the combination degree of the hydrophobic volatile oil in hydrophilic traditional Chinese medicine particles (soft materials) are remarkably improved, and the problems that the antiviral volatile oil is unstable in component and poor in uniformity in a preparation are fundamentally solved.

The application relates to the technical field of pharmaceutical preparations, and provides an ivermectin external pharmaceutical composition, a preparation method and application.The ivermectin external pharmaceutical composition is mainly composed of ivermectin, a permeation enhancer combination, oil ingredients, an emulsifier, a viscosity regulator and a carrier; the ivermectin content is 0.60%-1.00% w / w; the permeation enhancer combination is a combination of diethylene glycol monoethyl ether, decyl umbelliferrone polyoxyethylene ether 8 and farnesol, and the content is 10%-15% w / w.The application overcomes the defects of the prior art, the composition not only has improved skin permeability and retention, but also is stable and non-greasy, and meanwhile, the production process has scalability, and can ensure uniform dispersion of active ingredients and auxiliary materials.

The invention belongs to the technical field of gel preparations, and particularly relates to an external gel preparation based on a pepper fragrance formula as well as a preparation method and application of the external gel preparation. The external gel preparation based on the pepper fragrance formula is prepared from rhizoma atractylodis, white pepper, fructus evodiae, clove, cinnamon, radix paeoniae alba and pericarpium arecae according to the weight ratio of (4-7): (2-4): (0.4-0.6): (2-4): (0.8-1.2): (0.5-1.5): (2-4). The externally-used gel preparation can be used for treating diarrhea, the effect is stable, the externally-used characteristic is suitable for treating infantile diarrhea, and the technical problems that traditional Chinese medicine volatile oil components are poor in water solubility and insufficient in stability are solved.

To provide a solid oil-resistant agent composition capable of providing an oil-resistant agent aqueous dispersion when used.SOLUTION: An oil-resistant composition comprising a liquid-repellent compound, a dispersant, and an excipient, wherein the oil-resistant composition is solid.SELECTED DRAWING: None

The invention discloses an encapsulated oil-in-water type composition and a preparation method thereof. The encapsulated oil-in-water type composition comprises the following components in percentage by weight: 0.1-1% of retinol; the oil-phase thickening agent is selected from one or more of dextrin palmitate, a castor oil / IPDI (isophorone diisocyanate) copolymer, an HDI (hexamethylene diisocyanate) / trihydroxymethyl hexyl lactone cross-linked polymer, glyceryl behenate, a hydrogenated (styrene / butadiene) copolymer and dibutyl lauroyl glutamine; the oil-phase thickening agent is selected from one or more of dextrin palmitate, a castor oil / IPDI (isophorone diisocyanate) copolymer, an HDI (hexamethylene diisocyanate) / trihydroxymethyl hexyl lactone cross-linked polymer, glyceryl behenate, a hydrogenated (styrene / butadiene) copolymer and dibutyl lauroyl glutamine; 10%-20% of an oil component, wherein the oil component comprises caprylic acid / capric triglyceride; 0.1%-5% of a rheology modifier; 5-20% of a humectant; and the balance of water. The capsule product has good slow release property. According to the composition disclosed by the invention, high-content addition and high-efficacy performance of the retinol are realized, meanwhile, good formula stability can also be realized, and the problem of skin irritation caused by the retinol is improved.

A plant-based extract complex composition having the properties for supporting the relief of musculoskeletal pain, antibacterial and anti-inflammatory is obtained from the process of forming a homogeneous mixing mixture by mixing in a specific order into a container including (A) a ginseng extract solution having a first percentage (%) by weight, (B) a medicinal herbs extract solution having a second percentage (%) by weight, (C) a plant-derived nanovesicles ingredient component having a third percentage (%) by weight, (D), a plant-derived essential oils ingredient having a fifth percentage (%) by weight (E) a methyl salicylate component having a fourth percentage (%) by weight, (F) an excipients component having a sixth percentage (%) by weight, and (G) water to create a mixture.

This invention belongs to the field of biopharmaceutical preparations, specifically relating to a sugar-free oral liquid for invigorating qi and nourishing blood and its preparation method. Using fifteen traditional Chinese medicines, including deer antler, codonopsis, astragalus, angelica, polygonatum, and yam, as core components, a sugar-free oral liquid for invigorating qi and nourishing blood is obtained. Deer antler, as the core medicinal material for invigorating essence and blood, is modified with chitosan complexation to enhance the water solubility, in vivo stability, and bioavailability of deer antler polypeptides. Codonopsis and astragalus synergistically regulate spleen and stomach function and form a synergistic effect with the blood-nourishing effect of angelica. Polygonatum and yam can regulate the body's immunity, optimize the spleen and stomach's digestive function, and balance the medicinal properties, achieving a highly effective and gentle effect of invigorating qi and nourishing blood. Furthermore, the excipient polyoxyethylene (35) castor oil can improve the solubility and formulation stability of poorly soluble components such as ginsenosides and deer antler polypeptides. β-cyclodextrin can encapsulate and protect the volatile oil components of angelica and tangerine peel and achieve slow release, forming a synergistic effect with the core components, ensuring a stable and lasting overall therapeutic effect.

The application discloses a continuous separation system and method for liquid aniline derivative intermediates, and the liquid aniline derivative intermediates are liquid 3-(N,N-diallyl) amino-4-methoxy acetanilide or liquid 3-(N,N-diethyl) amino acetanilide. The application can quickly separate product heavy oil, mother liquor water and floating oil components by using a continuous oil-water separator, a floating oil intermediate tank and a product oil intermediate tank. The emulsified materials in the mother liquor water can be effectively recovered by using the mother liquor intermediate tank for salting-out demulsification. The separated mother liquor clear liquid enters an MVR evaporation system, and ammonium chloride salt and distilled water are obtained through evaporation, concentration and crystallization. The ammonium chloride concentrate can be recycled for salting-out demulsification. After the liquid aniline derivative intermediate crude product is subjected to the continuous separation system and method, the separation efficiency of the liquid material is high, the overall material yield is improved, the solid content of the product is obviously improved, the system stability is good, and the wastewater treatment cost is reduced.

This invention belongs to the field of skincare product preparation technology and discloses a method for preparing skincare products containing butter. The method includes a Mongolian butter purification process and a skincare product molding process. The purification process involves separating the milk skin by allowing it to stand, fermenting to prepare sour cream, whipping to separate the raw butter, and boiling and purifying to obtain cosmetic-grade Mongolian butter. The molding process uses the purified Mongolian butter as the core, combined with natural moisturizing excipients and emulsifiers, and involves mixing, melting, emulsifying, low-temperature sterilization, cooling, and filling to obtain the finished product. Finally, after passing inspection, it is stored. This invention features a coherent process, strong feasibility, and can thoroughly remove allergenic impurities from the butter while retaining its natural nutritional activity. The prepared skincare product is natural, safe, gentle, and hypoallergenic, with excellent moisturizing, repairing, and antioxidant effects. It is suitable for dry, sensitive skin, as well as infant and post-cosmetic surgery damaged skin, and exhibits strong stability and a long shelf life.

The present application relates to the field of daily chemical products, and discloses a dandruff control and oil control composition and a preparation method thereof.The dandruff control and oil control composition comprises the following components: core components and excipients.The preparation method comprises the following steps: 1) raw material preparation;2) preparation of phase A;3) preparation of phase B;4) mixing;5) homogenization.The dandruff control and oil control composition provided by the present application is from the five dimensions of oil control, inhibition of malassezia, anti-inflammatory, moisturizing and antioxidant, through the addition of oil control components, dandruff control components and conditioning agents as core components, the balance of sebum secretion is maintained, the bacteriostatic effect can be achieved to achieve the dandruff control effect, and the composition components are mild and non-irritating.The preparation method provided by the present application not only improves the production efficiency and is simple in operation process, and is suitable for industrial production.

The application provides an oil-sensitive skin cleaning composition and a preparation method thereof, and relates to the technical field of skin care products. The composition comprises an oil control component, a soothing component, a sebum-like component, a water-soluble polymer, and an ambient fragrance component. The oil control component can remove oil, achieve oil control, and remove oil without removing water. The soothing component can increase the mildness of the formula and reduce the irritation of the formula. The sebum-like component can also achieve the effect of removing oil without removing water, protect the oil-sensitive skin during cleaning, prevent dryness and tightness of the skin caused by excessive cleaning, and remove oil without removing water. The water-soluble polymer component wraps or winds surfactant molecules, reduces the combination of free surfactant molecules and proteins in the cuticle, and thus reduces irritation. The soothing component soothes the skin that has contacted the cleaning composition and prevents inflammatory reactions. The ambient fragrance component plays a role in relieving stress, relaxing the body and mind, and promoting sleep while cleaning the skin.

The present invention relates to a nanoparticle formulation for coating the outer layer of a hair structure, the composition of which comprises a natural oil extract. The formula comprises rice bran oil, hydrogenated olive oil, olive oil (Olea eupaea fruit oil), unsaponified olive oil (Olea eupaea unsaponified fruit oil), a rice bran extract existing in a rice bran fat form, a nonionic surfactant, an emulsifier, sodium benzoate and deionized water. The formula can be used as an alternative material for hair care products, has a phase size of 150-200 nanometers, and aims to prevent protein loss of healthy hair caused by ultraviolet radiation and high temperature. The technology can be realized in a wet hair state or an outer layer structure without oil components by coating the outer layer of the hair structure in a targeted manner.

The invention discloses a purification device with an HPV inactivation effect for hawthorn kernel tar lotion production, and relates to the technical field of grease production, the purification device comprises a rack, a discharging frame is arranged on one side of the rack, a feeding frame is arranged on the other side of the rack, a rotating cylinder is rotatably connected in the rack, and a rotating shaft is arranged in the rotating cylinder. The two ends of the rotating cylinder communicate with the discharging frame and the feeding frame correspondingly. According to the invention, the first heating rod is used as an external heat source, and the second heating rods are circumferentially arranged at the center, so that a bidirectional synergistic heat radiation pattern from outside to inside and from inside to outside is formed, and the inherent defects of edge overheating carbonization and insufficient center pyrolysis of a traditional external heating type retort are effectively overcome. The hawthorn seed material is heated more uniformly, lignocellulose is cracked more sufficiently, the yield of light phenol components such as guaiacol with an HPV inactivation effect is remarkably improved, the consistency of batch-to-batch m-distillate components is enhanced, and the strict requirement of medicinal lotion for effect stability is met.

To provide a powdery solid cosmetic good in impact resistance and sense of use and excellent in color development, and to provide a method for producing the same.SOLUTION: A powder solid cosmetic comprising (A) a wax powder, (B) a powder ingredient (excluding the (A) wax powder), and (C) an oil ingredient, wherein the (B) powder ingredient comprises (b1) nonporous silica, and the (C) oil ingredient comprises 15 to 50% by mass of a non-volatile dimethicone having a (c1) viscosity of 10cs or less relative to the total amount of the cosmetic, and a method for producing the powder solid cosmetic using wet molding.SELECTED DRAWING: None

This invention discloses a medicinal and edible homologous composition and its application in the preparation of drugs or foods for improving chronic lung diseases, belonging to the field of pharmaceutical technology. The medicinal and edible homologous composition of this invention uses donkey-hide gelatin and astragalus as the principal ingredient, apricot kernel and burdock seed as the assistant ingredient, loquat leaf as the adjuvant ingredient, and platycodon and licorice as the auxiliary and guiding ingredients. Through the use of volatile oil extraction and re-addition techniques, as well as the separate "melting" of donkey-hide gelatin, the heat-sensitive volatile oil components in the raw medicinal materials are preserved, and a networked regulatory mode of "synthesis promotion-degradation inhibition-signal enhancement" is constructed, achieving deep activation of the cAMP pathway. The medicinal and edible homologous composition has pharmacological activities that improve lung function and inhibit airway inflammation. The activity is significantly superior to that of donkey-hide gelatin, roflumilast, and hormones used alone; the medicinal and edible homologous composition exhibits excellent synergistic effects in the treatment of COPD and asthma, and has improving and therapeutic effects on chronic lung diseases induced by inflammation, bronchoconstriction, and mucus secretion, and can delay the progression of COPD and asthma, providing a new approach and direction for the preparation of drugs or foods that improve chronic lung diseases; this invention can provide core technical support for the secondary development of traditional Chinese medicine compound prescriptions and the creation of new drugs, thereby effectively promoting the modernization of traditional Chinese medicine.

The invention discloses a micron emulsion-in-situ gel composite preparation as well as a preparation method and application thereof, and belongs to the technical field of pharmaceutical preparations. The compound preparation comprises temperature-sensitive gel and micron emulsion dispersed in the temperature-sensitive gel, the micron emulsion consists of an oil-phase raw material and a water-phase raw material. Mixing essential oil, medium chain triglyceride and an antioxidant, and stirring until the mixture is clarified to obtain an oil phase; dissolving an emulsifier, a humectant, a bactericide and a metal ion chelating agent in water to obtain a water phase; adding the oil phase into the water phase, and shearing to obtain micron emulsion; and mixing the micron emulsion with a temperature-sensitive gel matrix aqueous solution to obtain the composite preparation. The compound preparation provided by the invention can obviously prolong the residence time of the medicine in nasal mucosa; the loading capacity and the chemical stability of hydrophobic, volatile and unstable essential oil components are improved; through the structural design of the preparation, the effective regulation and control of the drug release behavior are realized, and the preparation is a dosage form with good administration compliance and storage stability.

The invention relates to all-natural bionic microcapsule loaded water-soluble active matter functional grease as well as a preparation method and application thereof. According to the invention, all-natural bionic micro-capsules are constructed, water-soluble active components are encapsulated in hydrophilic cavities inside the micro-capsules, and then the micro-capsules are integrated into natural vegetable fat, so that stable coexistence and directional carrying of water and oil components are realized on the microscopic scale. The compatibility problem of water-soluble active matter and natural grease is solved, and meanwhile the natural property of the formula is reserved.

To provide an oil-soluble antioxidant composition having high antioxidant activity. [Solution] An oil-in-oil droplet type oil-soluble antioxidant composition in which an aqueous phase containing gallic acid, tea catechins, glycerin, and water is emulsified in an oil phase containing a lipophilic emulsifier, glycerin, and oil components, and which does not contain an oil-soluble antioxidant.

The present disclosure relates to a pharmaceutical composition comprising an SMTP derivative. Specifically, the present disclosure relates to a fat emulsion, comprising: a compound represented by formula I or a pharmaceutically acceptable salt thereof, an oil component, water, and a first emulsifier. The pharmaceutical composition can be better applied in clinic practice.