This invention discloses a medicinal and edible homologous composition and its application in the preparation of drugs or foods for improving chronic
lung diseases, belonging to the field of
pharmaceutical technology. The medicinal and edible homologous composition of this invention uses
donkey-hide
gelatin and
astragalus as the principal ingredient,
apricot kernel and burdock seed as the assistant ingredient,
loquat leaf as the
adjuvant ingredient, and platycodon and licorice as the auxiliary and guiding ingredients. Through the use of volatile oil extraction and re-addition techniques, as well as the separate "melting" of
donkey-hide
gelatin, the heat-sensitive volatile oil components in the raw medicinal materials are preserved, and a networked regulatory mode of "synthesis promotion-degradation inhibition-
signal enhancement" is constructed, achieving deep activation of the cAMP pathway. The medicinal and edible homologous composition has pharmacological activities that improve
lung function and inhibit
airway inflammation. The activity is significantly superior to that of
donkey-hide
gelatin,
roflumilast, and hormones used alone; the medicinal and edible homologous composition exhibits excellent synergistic effects in the treatment of
COPD and
asthma, and has improving and therapeutic effects on chronic
lung diseases induced by
inflammation,
bronchoconstriction, and
mucus secretion, and can
delay the progression of
COPD and
asthma, providing a new approach and direction for the preparation of drugs or foods that improve chronic lung diseases; this invention can provide core
technical support for the
secondary development of
traditional Chinese medicine compound prescriptions and the creation of new drugs, thereby effectively promoting the modernization of
traditional Chinese medicine.