Vesicle transport method for targeted anti-aging repair

A vesicular, targeted technology for skin repair

Pending Publication Date: 2021-02-12
VSH SKIN ANTI AGING LAB CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the process of various nutrients and growth factors entering cells,...

Method used

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  • Vesicle transport method for targeted anti-aging repair
  • Vesicle transport method for targeted anti-aging repair
  • Vesicle transport method for targeted anti-aging repair

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] This example 1 provides a vesicle transport method for targeted anti-aging repair. The vesicle bionic components are divided into nano-sized liposome globules, which are coated with cell activity promoting factors and tissue repair factors to achieve membrane Fusion repair and cell-to-cell trafficking.

[0048] The water-based cavities of the liposome globules are covered with water-soluble macromolecular substances, and fat-soluble or both water-soluble and fat-soluble substances are combined in the lipid bimolecules or lipophilic groups.

[0049] The cell activity-promoting factor has a natural receptor in the human body, and after realizing the fusion of the microlipid vesicle and the globular membrane, it is efficiently combined with the skin cell receptor through the vesicle transport system.

[0050] The tissue repair factor is a key signaling molecule in the intracellular oxidative stress pathway, activates various protein kinases and transcription factors, parti...

Embodiment 2

[0054] Example 2 provides a method for targeted anti-aging repair, including vesicle transport; channel recognition and opening, induction activation and damage repair process.

[0055] In the process of channel identification and opening, the moisturizing factor and liposome globules are used to complete channel identification and opening, so as to realize the transport of substances across the skin barrier and across the cell membrane.

[0056] The moisturizing factor is hyaluronic acid; the hyaluronic acid includes high molecular weight hyaluronic acid, middle molecular weight hyaluronic acid and low molecular weight hyaluronic acid; the high molecular weight hyaluronic acid refers to sodium hyaluronate; The hyaluronic acid of the middle molecular weight refers to hydroxypropyl trimethyl ammonium chloride hyaluronic acid; The hyaluronic acid of the low molecular weight refers to hydrolyzed hyaluronic acid; The hyaluronic acid of the high molecular weight, the hyaluronic acid...

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Abstract

The invention provides a vesicle transport method for targeted anti-aging repair on the first hand, and the vesicle transport method comprises the steps: dividing vesicle bionic components into nano-scale lipocyst globules which are wrapped with cell activity promoting factors and tissue repair factors, so membrane fusion repair and intercellular transport are realized. The cell activity promotingfactor has a natural receptor in a human body, and is efficiently combined with a skin cell receptor through a vesicle transport system after being fused with a lipid vesicle globule membrane; the tissue repair factor is a key signal molecule of an intracellular oxidative stress pathway, activates various protein kinases and transcription factors, participates in intracellular signal transduction, and performs membrane fusion repair, so that nutrient substances are more accurately fused and released with target cells, the repair capacity of skin cells is effectively improved, and the problemsof skin damage and aging are solved.

Description

technical field [0001] The present invention relates to the technical field related to skin repair, and more specifically, the present invention provides a vesicle transport method for targeted anti-aging repair. Background technique [0002] Skin aging, as the first and most noticeable aging process of the human body, is the comprehensive result and external manifestation of the aging of the overall function, and it is the result of continuous accumulation of skin undergoing a series of damages that have not been fully repaired. At present, human's understanding of skin aging has advanced to the cellular and molecular level. Insufficient material and energy supply of skin cells, resulting in skin damage that cannot be repaired in time, is the main cause of skin aging. [0003] Several important biological processes exist in skin aging, such as alteration and stabilization of DNA repair, mitochondrial function, cell cycle and apoptosis, lipid synthesis, proteolysis induced b...

Claims

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Application Information

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IPC IPC(8): A61K8/14A61Q19/08A61Q19/00A61K8/35A61K8/67A61K8/68A61K8/73
CPCA61K8/14A61Q19/08A61Q19/00A61K8/671A61K8/68A61K8/735A61K8/355A61K8/678
Inventor 不公告发明人
Owner VSH SKIN ANTI AGING LAB CO LTD
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