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Marine oligosaccharide-containing composition for preventing and treating gout

A marine oligosaccharide and composition technology, applied in the field of marine biology, can solve problems such as toxic and side effects, and achieve the effects of easy supply of raw materials, reducing inflammatory response, and alleviating the induction of gouty arthritis

Pending Publication Date: 2021-03-26
QINGDAO BZ OLIGO BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These drugs achieve the purpose of relieving or treating gout and hyperuricemia through different action links, but more and more clinical observations have found that they all have certain toxic and side effects

Method used

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  • Marine oligosaccharide-containing composition for preventing and treating gout
  • Marine oligosaccharide-containing composition for preventing and treating gout
  • Marine oligosaccharide-containing composition for preventing and treating gout

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A composition containing marine oligosaccharides for preventing and treating gout comprises chitosan oligosaccharides and mannuronic acid oligosaccharides, wherein the ratio of chitosan oligosaccharides to mannuronic acid oligosaccharides is 5:1.

Embodiment 2

[0027] A composition containing marine oligosaccharides for preventing and treating gout comprises chitosan oligosaccharides and mannuronic acid oligosaccharides, wherein the ratio of chitosan oligosaccharides to mannuronic acid oligosaccharides is 2:1.

Embodiment 3

[0029] A composition containing marine oligosaccharides for preventing and treating gout comprises chitosan oligosaccharides and mannuronic acid oligosaccharides, wherein the ratio of chitosan oligosaccharides to mannuronic acid oligosaccharides is 1:1.

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Abstract

The invention discloses a marine oligosaccharide-containing composition for preventing and treating gout. The marine oligosaccharide-containing composition is prepared from marine oligosaccharide as amain active ingredient. The marine oligosaccharide is a small molecular sugar chain obtained by degrading marine animal polysaccharide, algal polysaccharide and microbial polysaccharide with chemicaland biological enzyme methods, and mainly comprises chitosan oligosaccharide, mannuronic acid oligosaccharide, guluronic acid oligosaccharide, agar oligosaccharide, neoagaro-oligosaccharide, carrageenan oligosaccharide and the like. Test results show that the marine oligosaccharide can certainly inhibit the effect of mouse liver xanthine oxidase XOD, reduce in-vivo generation of uric acid, reducedeposition of urate substances in the kidney, accelerate uric acid metabolism and relieve gouty arthritis induced by sodium urate. Besides, the marine oligosaccharide can also reduce inflammatory response, improve body immunity and play a certain role in easing pain, is used for preparing drugs or health care products for preventing and treating gout, and can provide a natural or nature-imitateddrug for preventing and treating gout, so that adverse reactions caused by using the gout drugs are reduced.

Description

technical field [0001] The invention discloses a composition containing marine oligosaccharides for preventing and treating gout, and specifically belongs to the technical field of marine biology. Background technique [0002] Gout is a disease in which urate is deposited in tissues due to metabolic disorders, increased blood uric acid levels and / or decreased excretion of uric acid. Clinically, gout is mainly characterized by hyperuricemia, manifested as recurrent arthritis, tophi formation and joint deformity, severe cases can cause joint mobility disorders, and chronic interstitial nephritis and uric acid nephritis can be caused when the kidney is involved. stone disease. Hyperuricemia is the biochemical basis of gout, and gout must be accompanied by hyperuricemia. In recent years, the incidence of gout and hyperuricemia is on the rise, and the age of onset is getting younger. They are closely related to the occurrence of hypertension, hyperlipidemia, atherosclerosis, an...

Claims

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Application Information

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IPC IPC(8): A61K31/702A61K31/734A61K31/722A61P19/06A23L33/125A23L2/52
CPCA61K31/702A61K31/734A61K31/722A61P19/06A23L33/125A23L2/52A23V2002/00A61K2300/00A23V2200/30A23V2200/324A23V2250/28
Inventor 徐小龙张斌管昶王丽丽张娜娜高芹芹
Owner QINGDAO BZ OLIGO BIOTECH