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Application of indole and duck feed containing indole in maintaining duck intestinal health and/or preventing duck necrotic enteritis

A technology for necrotic enteritis and intestinal health, applied in the field of prevention of duck necrotic enteritis, to achieve the effect of reducing the use of antibiotics and avoiding antibiotic residues

Active Publication Date: 2021-04-30
JIANGSU AGRI ANIMAL HUSBANDRY VOCATIONAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Thus, the present invention provides a solution to the problems associated with duck gut health and / or duck necrotic enteritis

Method used

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  • Application of indole and duck feed containing indole in maintaining duck intestinal health and/or preventing duck necrotic enteritis
  • Application of indole and duck feed containing indole in maintaining duck intestinal health and/or preventing duck necrotic enteritis
  • Application of indole and duck feed containing indole in maintaining duck intestinal health and/or preventing duck necrotic enteritis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Embodiment 1: the preparation of duck feed

[0050] Formulate duck feed through the following steps:

[0051] S1: Break food-grade indole with a microcomputer, and sieve with a 40-mesh woven sieve to obtain indole with a particle size of less than 0.425mm;

[0052] S2: Remove the indole obtained by the S1 step treatment in the weight of the indole premix given in Table 1 respectively, and mix it with the bran of the corresponding weight ratio to obtain indole with different indole content Indole premix;

[0053] S3: Pulverize and uniformly mix the ingredients given in the following table 1 in terms of the weight of the duck powder, thereby obtaining self-prepared duck powder; optionally, according to the data given in the following table 1, In addition, add lactobacillus plantarum based on the weight of duck powder;

[0054] S4: Take 50g of each indole premix obtained in the S2 step and 950g of the respective duck powders obtained in the S3 step, add and mix step by ...

Embodiment 2

[0056] Embodiment 2: the toxicity test of indole to duck

[0057] Toxicity test was carried out on 20 22-day-old Gaoyou ducks (10 males and 10 females) to observe whether indole is toxic to ducks. Specifically, raise Gaoyou ducks (5 males and females in each group) with the feed (not containing indole) of the control group 1 prepared in Example 1 and the feed of the toxicity test group (the weight percentage of indole is 0.05%), and continuously Raising for 7 days. After 7 days, three male ducks and three female ducks in the control group and poison test group were randomly dissected.

[0058] It was found by visual inspection that the internal organs obtained from the poison test group did not change compared with the control group. At the same time, the blood biochemical indicators of the control group and the toxicity test group were also detected, and the results are shown in Table 2 below. The results showed that there was no significant difference between the data of ...

Embodiment 3

[0062] Example 3: Intestinal health promotion test of indole

[0063] The experiment adopts single factor design, and the only variable is the content of indole in duck feed.

[0064] Specifically, 280 18-day-old Gaoyou ducks with similar body weight were randomly selected and divided into 4 groups, half male and half female.

[0065] The pre-feeding period was 4 days, and the feed was the feed of the control group 1 in Table 1 in Example 1, that is, no indole; the test period was 28 days, starting from the age of 22 days to the end of the age of 49 days. During the whole test period, all ducks had free access to powder and drinking water, and the diet and feeding management were in accordance with the local standard of Gaoyou Duck Feeding Technical Regulations (DB32 / T910-2006). The daily feed intake of ducks is usually 90g to 100g.

[0066] The test is divided into control group 1, test group 1, test group 2 and test group 3, and the ingredients of the feed are shown in the...

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Abstract

The invention relates to an application of indole and a duck feed containing indole in maintaining duck intestinal health and / or preventing duck necrotic enteritis , especially duck necrotic enteritis caused by clostridium perfringens type A. The active substances are explored, found and applied to protect the duck intestinal health, important significance for preventing epidemic diseases and ensuring the development of the duck breeding industry is achieved, and beneficial reference is provided for solving the problems of bacterial drug resistance and antibiotic residues caused by abuse of antibiotics in the breeding industry.

Description

technical field [0001] The invention relates to the technical field of green breeding of duck industry, in particular to the field of intestinal health of ducks, and more specifically to the use of indole as an additive for duck feed to maintain duck intestinal health and / or prevent duck necrotic enteritis and its use. Instructions. Background technique [0002] Duck necrotizing enteritis is an infectious disease of the digestive tract that occurs throughout the year. The typical clinical symptoms of the disease are dark brown tar-like feces from sick ducks, accompanied by blood or intestinal mucosal tissue in the feces. The tissue is characterized by mucosal ulceration and necrosis, and the mortality rate of the disease can reach up to 30%, which has caused huge losses to the duck industry in China [1] . The transmission route of duck necrotic enteritis is mainly the feces excreted by sick ducks, so feeding management, cleanliness and sanitation are closely related to the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/404A61P1/00A61P31/04A23K50/75A23K10/30A23K10/37A23K10/22A23K10/26A23K20/22A23K20/132A23K10/18
CPCA61K31/404A61P1/00A61P31/04A23K50/75A23K10/30A23K10/37A23K10/22A23K10/26A23K20/22A23K20/132A23K10/18Y02P60/87
Inventor 闫伟李巨银周根来郁杰李永朱爱文
Owner JIANGSU AGRI ANIMAL HUSBANDRY VOCATIONAL COLLEGE
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