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Sampling system suitable for multi-channel terminal reflection type optical fiber SPR sensor and using method thereof

A sampling system and terminal reflection technology, applied in the field of sampling systems, can solve the problems of difficulty in detecting multiple samples at one time, low detection efficiency, etc., and achieve the effects of avoiding abnormal detection data, small dead volume, and improving detection efficiency.

Pending Publication Date: 2021-05-25
NINGBO HEIGER ELECTRICAL APPLIANCES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the traditional spectral modulation SPR sensor system can only realize a single detection channel, which is difficult to meet the needs of detecting multiple samples at a time, and the detection efficiency is low

Method used

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  • Sampling system suitable for multi-channel terminal reflection type optical fiber SPR sensor and using method thereof
  • Sampling system suitable for multi-channel terminal reflection type optical fiber SPR sensor and using method thereof
  • Sampling system suitable for multi-channel terminal reflection type optical fiber SPR sensor and using method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] As shown in the figure, a sampling system applicable to a multi-channel terminal reflection optical fiber SPR sensor of the present invention includes: a housing, a sampling mechanism installed in the housing for collecting and transporting the sample to be tested, for The optical fiber SPR detection mechanism located at the terminal reflective optical fiber SPR detection end for detecting the sample to be tested and the liquid discharge mechanism 13 for self-cleaning and discharging the detection waste liquid, the sampling mechanism is set at the front sampling end of the optical fiber SPR detection mechanism , the liquid discharge mechanism 13 is arranged at the rear side sample outlet end of the optical fiber SPR detection mechanism, and the sample feeding mechanism, the optical fiber SPR detection mechanism and the liquid discharge mechanism 13 are communicated through a capillary 21;

[0053] The sampling mechanism includes a sample tube 12 for containing the sample...

Embodiment 2

[0078] On the basis of Embodiment 1, the sampling needle is installed on the housing through a driving mechanism, and the driving mechanism includes a horizontally moving stepper motor and a vertically moving stepping motor for controlling the position movement of the sampling needle, so that the sampling needle Move to the required sample tube 12 to collect the sample to be tested.

[0079] Furthermore, a horizontal deep hole 30 is formed in the connection base 25 , and a sleeve 29 is inserted into the deep hole 30 , and the optical fiber is embedded in the sleeve 29 .

[0080] Furthermore, the inner diameter of the sleeve 29 is adjusted according to the outer diameter of the optical fiber, so as to match various optical fibers with different outer diameter specifications.

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Abstract

The invention discloses a sampling system suitable for a multi-channel terminal reflection type optical fiber SPR sensor. The system comprises a shell, a sample injection mechanism which is mounted in the shell and is used for collecting and conveying a sample to be detected, an optical fiber SPR detection mechanism which is used for detecting the sample to be detected and is positioned at a terminal reflection type optical fiber SPR detection end, and a liquid discharge mechanism which is used for self-cleaning and discharging detection waste liquid, and the sample injection mechanism is arranged at the front side sample injection end of the optical fiber SPR detection mechanism; and the liquid discharge mechanism is arranged at the rear side sample outlet end of the optical fiber SPR detection mechanism. The optical fiber channels connected in parallel are distributed on the same plane along the circumference at equal angles, it is guaranteed that sample flow paths of all the internal liquid paths are equal in length and small in dead volume, at least two optical fiber sensors are arranged in each optical fiber channel, the same sample can be sampled and detected at the same time or multiple samples can be sampled and detected, detection data of multiple groups of optical fiber sensors are detected, each internal liquid path is relatively independent and has parallelism, the consumption of samples is reduced, and the detection efficiency is improved.

Description

technical field [0001] The invention belongs to the technical field of SPR biosensing detectors, and in particular relates to a sampling system suitable for multi-channel terminal reflection optical fiber SPR sensors. Background technique [0002] Optical fiber surface plasmon resonance sensor (SPR) is the product of organically combining high-sensitivity surface plasmon resonance sensor technology with low energy consumption optical fiber transmission technology. It combines the SPR effect is very sensitive to the change of the refractive index of the environmental medium, and at the same time, the optical fiber itself is soft, bendable, electrically insulating, corrosion-resistant, does not generate heat or radiation during use, and can withstand strong electromagnetic interference and flammable Unique advantages such as working under complex environmental conditions such as explosive and toxic gases. When light enters an optically sparse medium from an optically denser m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/552G01N21/01
CPCG01N21/01G01N21/553
Inventor 丁利清江李明安王季诚
Owner NINGBO HEIGER ELECTRICAL APPLIANCES
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