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Rhinitis oil for treating allergic rhinitis and preparation method thereof

A technology for allergic rhinitis and rhinitis, which is applied in the field of rhinitis oil for the treatment of allergic rhinitis and its preparation, and can solve the problems of drowsiness, drowsiness, headache, dizziness, excitement, dry mouth and gastrointestinal discomfort, halving, after drinking Avoid use, drivers, operating machines or high-altitude workers with caution, mental system disorders and other problems, to achieve the effect of treating and preventing allergic rhinitis, relieving skin redness, and improving blood circulation

Inactive Publication Date: 2021-06-15
张占东
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these drugs have many side effects and are poorly tolerated by patients, such as:
[0003] (1) Antihistamines have anti-allergic effects and can relieve symptoms such as nasal itching, sneezing, and hypersecretion of the nose, but are less effective in relieving nasal congestion and have more side effects. For example, the side effects of cetirizine include drowsiness, lethargy, Headache, dizziness, agitation, dry mouth and gastrointestinal discomfort, etc., the dosage should be halved for those with renal impairment, avoid use after drinking, and use with caution by drivers, operators of machines or personnel working at heights; (2) Long-term use of nasal decongestants It may cause drug-induced rhinitis and can only be used for 7 days; (3) The most common side effects of anticholinergic drugs in clinical practice are non-respiratory system adverse reactions, manifested as headache, nausea, dry mouth, tachycardia, palpitations, eye adjustment disorders, Gastrointestinal motility disorder and urinary retention, etc., the side effects of anticholinergic drugs are rare and reversible, but the risk of urinary retention is increased for patients with existing urethral obstruction; there are also side effects on the eyes, manifested as increased intraocular pressure; and other inhaled drugs Like bronchodilators, it may cause coughing, local irritation, and rarely bronchoconstriction due to inhalation irritation. Allergic reactions such as rash, tongue, lip, facial angioedema, urticaria, and laryngospasm have also been reported; (4) nasal The use of glucocorticoids can lead to epistaxis, bronchospasm, cough, etc.; (5) anti-leukotriene drugs can cause upper respiratory tract infection and disorders of various body systems, blood and lymphatic system disorders, manifested as increased bleeding tendency; immune system disorders, Hypersensitivity reactions including anaphylaxis, rare hepatic eosinophilic infiltration; psychiatric disturbances including aggressive behavior or hostile agitation, anxiety, depression, disorientation, abnormal night dreams, hallucinations, insomnia, irritability , restlessness, sleepwalking, tremors, suicidal thoughts and behaviors; nervous system disturbances: manifested as dizziness, drowsiness, paresthesia, hypoesthesia, and rare seizures; cardiac disturbances, manifested as palpitations; respiratory, thoracic and mediastinal systems Disorders, manifested by epistaxis; gastrointestinal disturbances, manifested by diarrhea, dyspepsia, nausea, vomiting; hepatobiliary disturbances, manifested by elevated ALT and AST, very rare hepatitis (including cholestatic, hepatocellular, and mixed lesions); skin and subcutaneous tissue disorders manifested by angioedema, contusions, erythema nodosum, pruritus, rash, urticaria; musculoskeletal and connective tissue disorders manifested by arthralgia, myalgia including muscle spasms; other disorders And the administration site showed weakness, fatigue, edema, fever

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] A rhinitis oil for treating allergic rhinitis, comprising the following raw materials: 8 g of cocklebur, 10 g of geese, 12 g of magnolia, 10 g of Chuanqiong, 12 g of notoginseng, 120 mL of sunflower oil, 220 mL of sesame oil, and 220 mL of olive oil.

[0041] The preparation method comprises the following steps:

[0042] (1) Clean cocklebur, goose not eating grass and magnolia magnolia, dry, mix, grind into powder, and pass through a 100-mesh sieve to obtain traditional Chinese medicine powder;

[0043] (2) adding the traditional Chinese medicine powder in step (1) to sunflower oil and soaking for 5 hours, the soaking temperature is 35°C, and then boiled at 100°C for 3 hours;

[0044] (3) Add Chuanqiong, Panax notoginseng, sesame oil and olive oil, lower the temperature to 40°C, boil for 5 hours, cool and stand, filter, and sterilize with ultraviolet light for 2 hours to obtain rhinitis oil.

[0045] The method of using the rhinitis oil in this example: clean the nasal...

Embodiment 2

[0047] A rhinitis oil for treating allergic rhinitis, comprising the following raw materials: 7g of cocklebur, 8g of geese, 11g of magnolia, 9g of Chuanqiong, 10g of notoginseng, 110mL of sunflower oil, 210mL of sesame oil, and 210mL of olive oil.

[0048] The preparation method comprises the following steps:

[0049] (1) Clean cocklebur, goose not eating grass and magnolia magnolia, dry, mix, grind into powder, and pass through a 100-mesh sieve to obtain traditional Chinese medicine powder;

[0050] (2) adding the traditional Chinese medicine powder in step (1) into sunflower oil and soaking for 5 hours, the soaking temperature is 35°C, and then boiled at 90°C for 3.5 hours;

[0051] (3) Add Chuanqiong, Panax notoginseng, sesame oil and olive oil, lower the temperature to 45°C, boil for 4.5 hours, cool and let stand, filter, and sterilize with ultraviolet light for 2 hours to obtain rhinitis oil.

[0052] The method of using the rhinitis oil in this example: clean the nasal ...

Embodiment 3

[0054] A rhinitis oil for treating allergic rhinitis, comprising the following raw materials: 5g of cocklebur, 6g of geese, 10g of magnolia, 8g of Chuanqiong, 9g of notoginseng, 100mL of sunflower oil, 200mL of sesame oil, and 200mL of olive oil.

[0055] The preparation method comprises the following steps:

[0056] (1) Clean cocklebur, goose not eating grass and magnolia magnolia, dry, mix, grind into powder, and pass through a 80-mesh sieve to obtain traditional Chinese medicine powder;

[0057] (2) adding the traditional Chinese medicine powder in step (1) to sunflower oil and soaking for 6 hours, the soaking temperature is 30°C, and then boiled at 80°C for 4 hours;

[0058] (3) Add Chuanqiong, Panax notoginseng, sesame oil and olive oil, lower the temperature to 50°C, boil for 4 hours, cool and let stand, filter, and sterilize with ultraviolet light for 1 hour to obtain rhinitis oil.

[0059] The method of using the rhinitis oil in this example: clean the nasal cavity, a...

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PUM

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Abstract

The invention relates to the technical field of traditional Chinese medicines, in particular to rhinitis oil for treating allergic rhinitis and a preparation method thereof. The rhinitis oil comprises the following raw materials of cocklebur fruit, centipeda minima, biond magnolia flower, ligusticum chuanxiong hort, pseudo-ginseng, sunflower seed oil, sesame oil and olive oil. According to the rhinitis oil, cocklebur fruit, centipeda minima and biond magnolia flower are firstly adopted for relieving swelling and pain, clearing away heat and toxic materials, and relieving pain and discomfort caused by allergic rhinitis; ligusticum chuanxiong hort, pseudo-ginseng, sesame oil and olive oil are compounded, blood vessels can be expanded, nasal blood circulation can be improved, the oxygen absorption capacity of tissues can be enhanced, and the nose can be helped to return to normal; in addition, sesame oil and olive oil can form a layer of protective film on the surface of nasal mucosa to isolate allergens, and therefore the effect of treating and preventing allergic rhinitis is achieved; finally, sunflower seed oil is adopted to relieve skin redness, swelling and chapping caused by dry nose and running nose; and the rhinitis oil has prevention and treatment effects on injuries caused by nasal dryness and rhinorrhea, and is low in cost, free of side effects and not prone to relapse.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a rhinitis oil for treating allergic rhinitis and a preparation method thereof. Background technique [0002] Clinically, according to the classification and degree of allergic rhinitis, a step-by-step treatment method is adopted, that is, antihistamine drugs, glucocorticoids, etc. are used for treatment step by step according to the severity of the disease. The main treatment methods include avoiding contact with allergens, drug therapy, immunotherapy, and surgical treatment. However, these drugs have many side effects and are poorly tolerated by patients, such as: [0003] (1) Antihistamines have anti-allergic effects and can relieve symptoms such as nasal itching, sneezing, and hypersecretion of the nose, but are less effective in relieving nasal congestion and have more side effects. For example, the side effects of cetirizine include drowsiness, lethar...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/575A61P11/02A61P37/08A61K9/00A61K36/185A61K36/236A61K36/258A61K36/28A61K36/32
CPCA61K9/0043A61K36/185A61K36/236A61K36/258A61K36/28A61K36/32A61K36/575A61K2236/35A61P11/02A61P37/08A61K2300/00
Inventor 张占东
Owner 张占东
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