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Formula granules containing fiber Mongolian medicine powder and preparation method thereof

A technology of formula granules and Mongolian medicine powder, applied in the field of Mongolian medicine, can solve the problems of poor processing performance of Mongolian medicines containing fibers, and achieve the effects of ensuring safety and effectiveness, improving compliance, and improving controllability and stability.

Active Publication Date: 2021-06-22
那生桑 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] In view of this, the object of the present invention is to provide fiber-containing Mongolian medicine powder formula granules and a preparation method thereof. The fiber-containing Mongolian medicine powder formula granules solve the problem of poor processing performance of fiber-containing Mongolian medicines and improve the dosage of fiber-containing Mongolian medicines. compliance; the preparation method of the fiber-containing Mongolian medicine comprehensively improves the quality controllability and stability of the fiber-containing Mongolian medicine pieces, and ensures the safety and effectiveness of the fiber-containing Mongolian medicine

Method used

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  • Formula granules containing fiber Mongolian medicine powder and preparation method thereof
  • Formula granules containing fiber Mongolian medicine powder and preparation method thereof
  • Formula granules containing fiber Mongolian medicine powder and preparation method thereof

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preparation example Construction

[0041] The invention provides a preparation method of the fiber-containing Mongolian medicine powder formula granules, comprising the following steps: 1) pulverizing the fiber-containing Mongolian medicine powder to obtain fiber-containing Mongolian medicine powder, and 2) mixing the fiber-containing Mongolian medicine powder and powdered sugar After mixing and wetting with starch slurry, wet granulation is carried out to obtain fiber-containing Mongolian medicine powder formula granules.

[0042] In the present invention, fiber-containing Mongolian medicine is pulverized to obtain fiber-containing Mongolian medicine powder. In the present invention, the pulverization is preferably carried out by an impact pulverizer, which has a large capacity of vibrating sieve and has a better pulverization effect on fiber-containing Mongolian medicines with certain toughness and elasticity. In the present invention, the pulverization preferably further includes passing the pulverized mater...

Embodiment 1

[0048] Preparation of Chuanmuxiang Granules

[0049] Weigh 35 kg of chuanbaxiang decoction pieces, pulverize with an impact mill, use an electromagnetic vibrating sieve to sieve chuanbaxiang powder, pass through a 100-mesh sieve, and collect the sieve to obtain 33.5 kg of chuanbaxiang powder.

[0050] Mix 7.5 kg of Kawasaki powder and 2 kg of powdered sugar in a swing mixer for 30 minutes to obtain a mixed material. Wet the mixed material with 5kg of 10% starch slurry, place it in a granulator for wet granulation, granulate with 14-16 mesh, dry at 60°C until the moisture content is ≤9%, and granulate with 18-20 mesh.

[0051] The prepared Chuanmuxiang granule preparation is packaged and inspected for quality; the packaging material is a pharmaceutical transparent polyethylene bottle or a pharmaceutical PVC special bag designated by the state, and the specification is 250-300g / bottle or 250-300g / bag.

[0052] According to the "Chinese Pharmacopoeia" (2020 edition of the four g...

Embodiment 2

[0068] Preparation of rhubarb granules

[0069] The rhubarb decoction pieces were weighed 35kg, pulverized by an impact mill, and the rhubarb powder was sieved by an electromagnetic vibrating sieve, passed through a 100-mesh sieve, and 33.5 kg of the rhubarb powder was obtained by collecting the under-sieve.

[0070] Mix 7.5 kg of rhubarb powder and 2 kg of powdered sugar for 30 minutes to obtain a mixed material. Wet the mixed material with 5kg of 10% starch slurry, place it in a granulator for wet granulation, granulate with 14-16 mesh, dry at 60°C until the moisture content is ≤9%, and granulate with 18-20 mesh.

[0071] The prepared rhubarb granules are packaged and inspected; the packaging material is a nationally designated transparent polyethylene bottle for medicine or a special PVC bag for medicine, and the specification is 250-300g / bottle or 250-300g / bag.

[0072] According to the "Chinese Pharmacopoeia" (2020 edition of the four general rules 0104) for inspection. ...

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Abstract

The invention provides fiber-containing Mongolian medicine powder formula granules and a preparation method thereof, and belongs to the technical field of Mongolian medicine preparations, and the mass ratio of fiber Mongolian medicine, powdered sugar and starch slurry in the fiber-containing Mongolian medicine powder formula granules is (73-77): (18-22): (45-55); the mass percentage content of the fiber Mongolian medicine in the fiber Mongolian medicine powder formula granules is 74.8%-75.1%. The fiber-containing Mongolian medicine powder formula granules provided by the invention are prepared by taking traditional single fiber-containing Mongolian medicine decoction parts as raw materials through the steps of crushing, adding auxiliary materials, granulating and the like. The Mongolian medicine single decoction parts are processed into the novel formula granules by applying a modern pharmacy method aiming at the purpose of not changing the medicine material basis in national medicine research and development, and the quality controllability and stability of the Mongolian medicine decoction parts are comprehensively improved on the premise of completely retaining the traditional attributes and clinical medication habits of the Mongolian medicine, so that the safety and effectiveness of the Mongolian medicine are guaranteed.

Description

technical field [0001] The invention belongs to the technical field of Mongolian medicine, and in particular relates to a fiber-containing Mongolian medicine powder formula granule and a preparation method thereof. Background technique [0002] Mongolian medicine is an important part of world and Chinese traditional medicine, and has distinct Mongolian cultural characteristics. Mongolian medicine has a long history, complete theory, and reliable curative effect. It is a unique traditional medicine system and occupies an important position in the national medical culture of our country. made a great contribution. Western medicine is helpless in the face of many modern diseases. In the process of seeking solutions, the concept of learning from nature has returned to the public eye. It happens that the natural attribute is the innate gene of Mongolian medicine, so Mongolian medicine is gaining momentum. [0003] The basic dosage form of traditional fiber-containing Mongolian ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/16A61K47/36A61K47/26A61K36/289A61K36/708A61K36/268A61K36/428A61K36/9068A61K36/48A61K36/756A61K36/47A61K36/533A61K36/73A61K36/716A61K36/185A61K36/67
CPCA61K9/1652A61K9/1623A61K9/1682A61K36/289A61K36/708A61K36/268A61K36/428A61K36/9068A61K36/48A61K36/756A61K36/47A61K36/533A61K36/73A61K36/716A61K36/185A61K36/67Y02A50/30
Inventor 王伟
Owner 那生桑
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