Multifunctional composite probiotic preparation as well as preparation method thereof

Abstract

The invention relates to a multifunctional composite probiotic preparation as well as a preparation method and the application thereof. The multifunctional composite probiotic preparation is prepared from lactobacillus plantarum MiuCul-01, lactobacillus acidophilus MiuLac-01, lactobacillus casei MiaoTech-01, lactobacillus rhamnosus MiaoTech-11, streptococcus thermophilus MiaoPro-01, bifidobacterium bifidum Miuyo-01, bifidobacterium lactis Miuyo-11, bifidobacterium infantis Miuyo-21 and bifidobacterium breve Miuyo-31, and the multifunctional composite probiotic preparation is prepared from lactobacillus plantarum MiuCul-01, lactobacillus acidophilus MiuLac-01, lactobacillus casei MiaoTech-01, lactobacillus rhamnosus MiaoTech-11, streptococcus thermophilus The composite probiotic preparation is prepared by a new process combining mixed bacteria inoculation, anaerobic liquid culture, solid-liquid separation, solid culture and the like, and the produced composite probiotic preparation is large in thallus quantity and high in activity, and contains metabolites generated by probiotics; the traditional Chinese medicine composition has better effects of resisting helicobacter pylori, reducing blood sugar, coordinating intestines and stomach, enhancing immunity, resisting allergy, reducing fat, losing weight and the like in human gastrointestinal tracts.

Description

technical field [0001] The invention belongs to the technical field of probiotic preparations, in particular to a multifunctional composite probiotic preparation and a preparation method thereof. Background technique [0002] Helicobacter pylori is a spiral-shaped, micro-anaerobic bacteria that requires very harsh growth conditions. Helicobacter pylori infection first causes chronic gastritis, and leads to gastric ulcer and gastric atrophy, and severe cases develop into gastric cancer. The common symptoms of patients with chronic gastritis and peptic ulcer are: fullness, discomfort or pain in the upper abdomen after eating, often accompanied by other adverse symptoms, such as belching, abdominal distension, acid reflux and loss of appetite. Some patients also have recurrent severe abdominal pain and a small amount of upper gastrointestinal bleeding. According to statistics: about 1% of patients with chronic gastritis and gastric ulcer will develop gastric cancer, and gastr...

AI Technical Summary

Problems solved by technology

But because the solid content in the liquid fermented liquid is very low (2-5%), so even if the added liquid culture liquid consumption reaches 50%, also can only add a small amount of liquid bacterial classification (1-2.5%) in the solid medium As a solid-state fermentation strain, the initial bacterial concentration in the solid-state fermentation medium is not high, resulting in a long solid-state fermentation time and a small concentration of viable bacteria in the product

[0012] To sum up, whether it is the traditional actual production process of probiotics "liquid culture + centrifugation" or the above-mentioned "liquid culture + solid state culture" process of the invention, there are low strain content, poor fermentation effect, and bacterial growth when dry. Defects such as high mortality rate and low bacterial viability in the finished product

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