SMILE lens staining low-temperature separation, application and use method thereof

A separation liquid and lens technology, applied in the field of ophthalmic refractive surgery, can solve the problems of corneal stromal lens separation difficulties, wrong lens shovel entry, corneal incision tearing, etc., so as to alleviate secondary mechanical effects, reduce resistance, and reduce mechanical traction. The effect of pulling and friction

Active Publication Date: 2021-08-06
SHENZHEN HOSPITAL OF SOUTHERN MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Especially limited by the biomechanical conditions of the cornea, the surgical sequence must first separate the upper surface of the corneal stroma lens, and then separate the lower surface of the corneal stroma lens. Once the order is wrong or the lens separation technique is improperly operated, it is easy to cause the lens shovel to enter the wrong layer or Separation of the interlayer, resulting in difficulty in separation of the corneal stroma lens, breakage, damage to the corneal cap (cap) and tearing of the corneal incision, etc., which in turn lead to different degrees of clinical complications

Method used

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  • SMILE lens staining low-temperature separation, application and use method thereof
  • SMILE lens staining low-temperature separation, application and use method thereof

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Embodiment Construction

[0018] It should be noted that, in the embodiments of the present application, OBL (opaque bubble layers) refers to the aggregates of bubbles gathered between the corneal layers, and is the water vapor generated when the femtosecond laser light blasts in the tissue. and CO 2 Formed by the diffusion of gaps between collagen fibers above or below the cutting plane, it is an undesirable clinical phenomenon that occurs during femtosecond laser corneal surgery.

[0019] In the embodiment of this application, DLK (diffuse lamellar keratitis) refers to non-infectious, diffuse subcap inflammatory cell infiltration between corneal layers after laser corneal refractive surgery. After 24 hours, it showed as fine white particle-like turbidity.

[0020] The application and its beneficial effects will be further described in detail below in conjunction with the embodiments.

[0021] This embodiment provides a low-temperature separation liquid for SMILE lens dyeing. The SMILE lens dyeing l...

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Abstract

The invention relates to an SMILE lens staining low-temperature separation, and an application and use method thereof. The SMILE lens staining low-temperature separation is used at the temperature of 0-4 DEG C for staining, infiltrating and separating a lens in SMILE, and comprises a balanced salt solution and 0.005 mg / ml-0.5 mg / ml fluorescein sodium, and the balanced salt solution comprises the components of 0.29 mg / ml-0.8 mg / ml potassium chloride, 0.19 mg / ml-0.5 mg / ml calcium chloride, 0.25 mg / ml-0.35 mg / ml magnesium chloride, 0.3 mg / ml-0.45 mg / ml sodium acetate and 1.6 mg / ml-2.2 mg / ml sodium citrate. The SMILE lens staining low-temperature separation can stain and infiltrate a cornea cap (cap), a cornea stroma lens front surface (cap-lens layer and upper layer), a cornea stroma lens rear surface (lens-rear stroma layer and lower layer), a cornea cap incision and the like which are formed by femtosecond laser precise scanning light blasting cutting; and the cornea stroma lens upper and lower surfaces which are not easy to distinguish are visible, so that the separation operation difficulty of the cornea lens is reduced, the operation is more accurate, the time is shortened, main structures such as the cornea cap and a cornea stroma are protected, and operative complications are reduced.

Description

technical field [0001] The invention relates to the technical field of ophthalmic refractive surgery, in particular to a low-temperature separation liquid for SMILE lens dyeing, its application and its usage method. Background technique [0002] Small incision lenticule extraction (SMILE) with femtosecond laser is to use femtosecond laser to perform spatial scanning and micro-blast cutting on the corneal stroma to make it into a lens and remove it from the edge of the small incision (2-4mm). ) is taken out to complete a new type of refractive surgery that changes the curvature of the cornea. [0003] A large number of clinical and research data show that SMILE has excellent safety, stability and predictability, and the advantages of this "minimally invasive" corneal refractive surgery have attracted more and more attention. However, due to the limitations of the femtosecond laser, there is still a bridge-like connection between the corneal stromal lens and the adjacent tiss...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F9/008A61F9/01A61F9/00A61M37/00A61N7/00
CPCA61F9/00804A61F9/0008A61M37/00A61N7/00A61F2009/00872A61M2037/0007A61M2210/0612A61M2210/005
Inventor 黎颖莉李伟力符敏李晓霞席蕾梁静陈慧琼陈丽娜赵鹏越李雪
Owner SHENZHEN HOSPITAL OF SOUTHERN MEDICAL UNIV
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