Bismuth/barium titanate heterojunction for enhancing sonodynamic tumor resistance and preparation method thereof

A barium titanate and anti-tumor technology, which is applied in the direction of anti-tumor drugs, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problems of unfriendly environment, uneven coating, complicated process, etc., to achieve enhanced effect and promote Active oxygen generation, enhanced separation effect
CN113209290AActive Publication Date: 2021-08-06SOUTH CHINA UNIV OF TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SOUTH CHINA UNIV OF TECH
Publication Date
2021-08-06

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Abstract

The invention discloses a bismuth / barium titanate heterojunction for enhancing sonodynamic tumor resistance and a preparation method thereof. The method comprises the following steps of (1), preparing barium titanate nanoparticles by a hydrothermal method; (2), performing high-temperature and high-pressure polarization treatment on the barium titanate nanoparticles; and (3), depositing bismuth elementary substances on the surfaces of the barium titanate nanoparticles by using a one-step in-situ deposition method to construct the bismuth / barium titanate P-N heterojunction. The bismuth / barium titanate heterojunction has good biocompatibility, high safety and good stability, and the sonodynamic tumor resistance effect can be enhanced.
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Description

technical field

[0001] The invention belongs to the technical field of tumor nanomaterials for sonodynamic therapy, and in particular relates to a bismuth / barium titanate heterojunction that enhances sonodynamic anti-tumor and a preparation method thereof. Background technique

[0002] Breast cancer seriously threatens the life and health of human beings, especially women. The current methods of clinical treatment of breast cancer mainly revolve around surgical resection, chemotherapy and radiotherapy. Surgical removal of the breast is usually the treatment of choice for breast cancer, but incomplete removal can lead to metastasis and recurrence of cancer. Chemotherapy and radiotherapy are often used as auxiliary means to remove tiny lesions, but the side effects will obviously lead to immunocompromised patients or poor therapeutic effect. Sonodynamic therapy (SDT) is a non-invasive, harmless and precise treatment method. The therapy uses ultrasound to activate the sonosen...

Claims

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