Fiber dressing with damaged skin repairing function and preparation method thereof

Abstract

The invention belongs to the technical field of medicines of medical dressings, and particularly relates to a fiber dressing with a damaged skin repairing function and a preparation method thereof. The preparation method comprises the following steps of (1) weighing polyvinyl alcohol, dissolving in 30% acetic acid, uniformly stirring to obtain a 2wt% solution, adding equivalent chitosan powder, and uniformly mixing under a magnetic stirrer to complete the preparation of a basic electrospinning solution; (2) adding ursolic acid, and uniformly stirring; and (3) carrying out electrostatic spinning by taking tin foil paper as a base material, and standing and drying an electrospun film after spinning to obtain the fiber dressing. According to the method, the concept of a traditional external application material is broken through, and the traditional Chinese medicines with low cost and high treatment effect are added into the external application material, so that the material has biological activity and plays anti-inflammatory, anti-oxidation and repair-promoting roles in the external application process.

Description

technical field [0001] The invention belongs to the technical field of medical dressings, and in particular relates to a fiber dressing with the function of repairing damaged skin and a preparation method thereof. Background technique [0002] The problem that the wounds of diabetic patients are susceptible to infection and difficult to heal is a difficult problem to be solved clinically. At present, the conventional methods for treating diabetic wounds are surgical debridement and dressing of wounds. Traditional gauze or cotton pads can dry out after absorbing bodily fluids produced by the wound. Moreover, during the repair process, new skin tissue will grow in from the gauze gap, so it is easy to cause secondary damage when replacing the new gauze. [0003] So far, with the development of technical research, many types of dressing materials have been sold on the market, such as: Vaseline gauze, semi-permeable membrane dressing, transparent film dressing, hydrophilic gel,...

AI Technical Summary

Problems solved by technology

However, most reported biomaterial dressings lack bioactivity

At present, a series of growth factors that promote proliferation have been added to the materials to show good therapeutic effects. At the same time, the side effects of growth factors on tissues, the inefficiency of the delivery system and the high price limit its clinical promotion.

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