System for noninvasive monitoring of cerebral blood flow

A technology of cerebral blood flow and induced current, applied in the field of non-invasive monitoring of cerebral blood flow, can solve the problems of development limitation, high detection cost, inconvenience of real-time continuous monitoring at the bedside, etc., and achieve the effect of high sensitivity

Active Publication Date: 2021-08-24
ARMY MEDICAL UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The spatial resolution of laser Doppler (LDF) imaging is limited, so the development is greatly restricted
Near-infrared spectroscopy (NIRS) uses the strong penetrating power of near-infrared light to enter biological tissues to transmit and scatter to measure cerebral blood flow. However, the current technology cannot rule out the low light transmittance of non-brain tissues such as scalp and hair. As well as the influence of scattering, the cerebral blood flow value measured by near-infrared spectroscopy is usually low, and the difference is obvious each time, so the average value of repeated measurements needs to be taken as a reliable value
[0005] To sum up, there are many methods for monitoring cerebral blood flow, some of which use cerebral angiography. This type of method is characterized by high measurement accuracy and accurate results. At the same time, the detection cost is relatively high, and it is not convenient for real-time continuous monitoring at the bedside. ; Some use the inert diffusion gas analysis method as the detection method, which is invasive and cannot be used for special patients

Method used

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  • System for noninvasive monitoring of cerebral blood flow
  • System for noninvasive monitoring of cerebral blood flow
  • System for noninvasive monitoring of cerebral blood flow

Examples

Experimental program
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Embodiment 1

[0052] see Figure 1 to Figure 5 , a system for non-invasive monitoring of cerebral blood flow, comprising a signal source, a sensor unit, a signal acquisition and processing unit and a storage unit.

[0053] The signal source sends an excitation signal to the sensor unit.

[0054] The signal source unit sends high-frequency AC sinusoidal excitation signals with a frequency range of [1MHZ, 100MHZ] to the first sensor and the second sensor respectively through the power divider.

[0055] The sensor unit includes a first sensor and a second sensor.

[0056] The second sensor is placed at the pterional point on the right side of the skull.

[0057] The sensor includes an exciting coil and a receiving coil. The excitation coil is located outside and is used for receiving excitation signals. The receiving coil is located inside and is used for receiving secondary magnetic field signals.

[0058] The sensors are flat PCB coils of the same specification.

[0059] The first sens...

Embodiment 2

[0090] A non-contact cerebral blood flow detection system based on magnetic induction, including an AC signal source unit, which can provide 1-100MHZ high-frequency AC sinusoidal signals for generating two-way excitation signals to the sensor unit to generate excitation magnetic fields and reference signals to signal acquisition with processing unit. The original signal of cerebral blood flow is obtained in the storage unit, and then processed by wavelet analysis, smoothing, and cubic spline interpolation to remove the baseline signal to obtain the cerebral blood flow signal.

[0091] 1) The sensor unit includes: the outside of a single sensor is an excitation coil, and the inside is a coaxial receiving coil. The excitation source provides 1-100MHZ high-frequency AC sinusoidal signals and enters the excitation coils of No. 1 and No. 2 sensors respectively through the power divider to generate alternating excitation magnetic fields. The excitation magnetic field signals are tra...

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Abstract

The invention discloses a system for noninvasive monitoring of cerebral blood flow. The system comprises a signal source, a sensor unit, a signal collecting and processing unit and a storage unit. The invention provides a non-contact magnetic induction type bedside long-time real-time cerebral blood flow monitoring system with high sensitivity, cerebral blood flow perfusion abnormity can be found in time, emergency measures are taken for control, and the non-contact magnetic induction type bedside long-time real-time cerebral blood flow monitoring system has important significance on effective treatment and reduction of cerebral function damage and death rate and improvement of the treatment level of cardiovascular patients.

Description

technical field [0001] The invention relates to the field of medical equipment technology and physiological signal acquisition and processing in the field of biomedical engineering, in particular to a system for non-invasive monitoring of cerebral blood flow. Background technique [0002] Cerebrovascular disease is a disorder of cerebral blood flow caused by stenosis, occlusion or rupture of intracranial arteries, which is clinically manifested as transient or permanent brain dysfunction. Cerebrovascular disease is a common and common disease that seriously threatens human health and life. It has high morbidity, disability, mortality and recurrence rates. It is one of the main diseases that cause disability and death in middle-aged and elderly people. . About 4.6 million people die from cerebrovascular disease every year in the world, which is the second leading cause of human death. Abnormal cerebral blood flow will seriously affect the function of the brain nervous syste...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/0265
CPCA61B5/0265A61B5/725A61B5/7225
Inventor 孙建张茂婷陈明生许佳李根陈镜伯白泽霖徐林庄伟王凤张海生谷珊珊宁旭秦明新
Owner ARMY MEDICAL UNIV
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