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Tea pigment composition and preparation method for treating cardiovascular and cerebrovascular diseases

A technology of tea pigment and composition, which is applied in the field of tea pigment composition and preparation, can solve the problem that the anti-oxidation and anti-inflammatory effects of anti-atherosclerosis treatment need to be further improved, the curative effect of anti-atherosclerosis is not clear, and the clinical adaptation Improve blood rheology, improve therapeutic effect, and high inclusion rate

Active Publication Date: 2022-07-08
生命之花(北京)健康管理有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Claims to have the effect of lowering blood sugar, blood pressure or blood lipid, but the prescription is complicated, the clinical adaptability is poor, and the curative effect on anti-atherosclerosis is not clear
[0006] Chinese invention patent CN101461896B discloses a traditional Chinese medicine composition for assisting in lowering blood fat and a preparation method thereof. The composition is composed of 4 g of ganoderma lucidum, 2 g of American ginseng, 3 g of notoginseng, 4 g of kudzu root, 2 g of hawthorn, 2 g of Polygonatum and 2 g of Polygonatum Polygonatum. The method has Certain blood lipid-lowering effects, but the antioxidant and anti-inflammatory effects in anti-atherosclerosis treatment need to be further improved

Method used

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  • Tea pigment composition and preparation method for treating cardiovascular and cerebrovascular diseases
  • Tea pigment composition and preparation method for treating cardiovascular and cerebrovascular diseases
  • Tea pigment composition and preparation method for treating cardiovascular and cerebrovascular diseases

Examples

Experimental program
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Effect test

Embodiment 1

[0031] A tea pigment composition for treating cardiovascular and cerebrovascular diseases, the raw material components are as follows: 5 parts of tea pigment, 5 parts of Cnidium, 10 parts of Panax notoginseng, 5 parts of American ginseng, 10 parts of Zelan, 10 parts of Polygonatum japonica, and 5 parts of Cornus officinalis , 10 parts of Ophiopogon japonicus and 10 parts of Gualou.

[0032] The preparation method is as follows:

[0033] (1) Add 8 times of water to extract volatile oil from Cnidium, Melon, American ginseng and Polygonatum japonica for 3h, filter to obtain volatile oil, filtrate a and filter residue a; add water to β-cyclodextrin to make 0.5g / mL β-cyclodextrin Aqueous solution, mix volatile oil and β-cyclodextrin solution, stir magnetically at 200 r / min for 1 h at a constant temperature of 55 ° C, cool, suction filter, and dry to obtain volatile oil inclusion compound; the mass ratio of volatile oil to β-cyclodextrin is 1: 5.5.

[0034] (2) Add 5 times the amo...

Embodiment 2

[0038] A tea pigment composition for the treatment of cardiovascular and cerebrovascular diseases, the raw material components are as follows: 10 parts of tea pigment, 8 parts of Cnidium, 15 parts of Panax notoginseng, 10 parts of American ginseng, 15 parts of Zelan, 15 parts of Polygonatum japonica, and 8 parts of Cornus officinalis , 15 parts of Ophiopogon japonicus and 15 parts of Gualou.

[0039] The preparation method is as follows:

[0040](1) Add 10 times the amount of water to extract volatile oil from Cnidium, Melon, American ginseng and Polygonatum japonica for 5 hours, and filter to obtain volatile oil, filtrate a and filter residue a; add water to β-cyclodextrin to make 0.5g / mL β-cyclodextrin Aqueous solution, mix volatile oil and β-cyclodextrin solution, stir magnetically at 200 r / min for 3 hours at a constant temperature of 65 °C, cool, filter with suction, and dry to obtain volatile oil inclusion compound; the mass ratio of volatile oil to β-cyclodextrin is 1: ...

Embodiment 3

[0045] A tea pigment composition for treating cardiovascular and cerebrovascular diseases, the raw material components are as follows: 8 parts of tea pigment, 5 parts of Cnidium, 15 parts of Panax notoginseng, 8 parts of American ginseng, 12 parts of Zelan, 10 parts of Polygonatum japonica, and 8 parts of Cornus officinalis , 10 parts of Ophiopogon japonicus and 12 parts of Gualou.

[0046] The preparation method is as follows:

[0047] (1) Add 8 times of water to extract volatile oil from Cnidium, Melon, American ginseng and Polygonatum japonica for 3h, and filter to obtain volatile oil, filtrate a and filter residue a; add water to β-cyclodextrin to make 0.5g / mL β-cyclodextrin Aqueous solution, mix volatile oil and β-cyclodextrin solution, stir magnetically at 200 r / min for 2 hours at a constant temperature of 60 °C, cool, filter with suction, and dry to obtain volatile oil inclusion compound; the mass ratio of volatile oil to β-cyclodextrin is 1: 6.

[0048] (2) Add 5 tim...

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Abstract

The invention belongs to the field of traditional Chinese medicine treatment for treating cardiovascular and cerebrovascular diseases, and particularly relates to a tea pigment composition for treating cardiovascular and cerebrovascular diseases, a preparation method and an application. The raw materials of the composition include the following components: 5-10 parts of tea pigment, 5-10 parts of Cnidium, 10-15 parts of Panax notoginseng, 5-10 parts of American ginseng, 10-15 parts of Zelan, and 10-15 parts of Polygonatum japonica servings, 5-10 servings of dogwood, 10-15 servings of Ophiopogon japonicus, and 10-15 servings of Gualou. The preparation method is as follows: firstly extracting volatile oil from Cnidium, Melon, American ginseng and Polygonatum, extracting the medicinal residues with Panax notoginseng, Zelan, Cornus and Ophiopogon japonicus, purifying, and finally mixing the extracts with tea pigments and auxiliary materials to obtain . The medicinal flavors of the present invention are organically compatible and have better effects on regulating blood lipids and improving blood rheology.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine treatment, and particularly relates to a tea pigment composition for treating cardiovascular and cerebrovascular diseases, a preparation method and an application. Background technique [0002] Cardiovascular and cerebrovascular diseases are collectively referred to as diseases of the heart and cerebrovascular. It generally refers to ischemic or hemorrhagic diseases of the heart, brain and systemic tissues caused by hyperlipidemia, blood viscosity, atherosclerosis and hypertension. The etiology and pathogenesis of anti-atherosclerosis (AS) are extremely complex, and the exact etiology and pathogenesis have not been determined so far. The recognized risk factors and pathogenesis are as follows: (1) lipid metabolism disorder; serum cholesterol The increase of is positively correlated with the occurrence of AS. With the in-depth study of lipoproteins, it is found that the level of LDL is...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8969A61K47/69A61P3/06A61P9/00A61P9/10A61K36/234A61K36/258
CPCA61K36/82A61K36/234A61K36/258A61K36/53A61K36/8969A61K36/40A61K36/8968A61K36/428A61K47/6951A61P9/10A61P9/00A61P3/06A61K2236/331A61K2236/333A61K2236/55A61K2300/00Y02A50/30
Inventor 郑涵席宾刘春颖
Owner 生命之花(北京)健康管理有限公司
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