Pure plant compound fructus lycii eyesight-improving nanometer eye protection patch and preparation method thereof
A pure plant and eye patch technology, applied in the direction of plant raw materials, skin care preparations, plant/algae/fungus/moss components, etc., can solve problems such as difficult absorption, ineffective use, and poor permeability of eye care and eye patches. Achieve the effect of simple and easy preparation method, good social and economic benefits, and ideal therapeutic effect
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Embodiment 1
[0045] The preparation method of wolfberry red liposome:
[0046] S1 takes 5 mg of lycium berry, 100 mg of lecithin, and ethanol and heats it in a water bath at 55°C until it is completely dissolved.
[0047] S2 was evacuated by a rotary evaporator and heated in a water bath at 60°C to prepare a honeycomb-like film.
[0048] S3 take 5ml ultrapure water as a hydration solution, heat the above-mentioned honeycomb film and the hydration solution to 45-60° C. in a water bath at the same time, then add the hydration solution to the film and mix, rotate using a rotary evaporator and heat in a water bath for 40-70 °C ℃, water bath evaporation for 10-15min, the film is completely dissolved in the hydration solution, ultrasonic for 5-10 minutes, 5%-10% power, to obtain the nanoliposomes encapsulating the lipid-soluble wolfberry active ingredient, its particle size, potential and Macro state as attached Figure 1-3 shown.
Embodiment 2
[0050] The preparation method of wolfberry seed oil liposome:
[0051] S1 Take 3 mg of wolfberry seed oil, 80 mg of lecithin, and ethanol and heat it in a water bath at 55°C until it is completely dissolved.
[0052] S2 was evacuated by a rotary evaporator and heated in a water bath at 60°C to prepare a honeycomb-like film.
[0053] S3 take 5ml ultrapure water as a hydration solution, heat the above-mentioned honeycomb film and the hydration solution to 45-60° C. in a water bath at the same time, then add the hydration solution to the film and mix, rotate using a rotary evaporator and heat in a water bath for 40-70 °C ℃, water bath evaporation for 10-15min, the film is completely dissolved in the hydration solution, ultrasonic for 5-10 minutes, 5%-10% power, to prepare nanoliposomes encapsulating lipid-soluble wolfberry active ingredients.
Embodiment 3
[0055] The preparation method of liposome encapsulating Lycium barbarum polysaccharide:
[0056] S1 Take 100 mg of lecithin and ethanol and heat it in a 55°C water bath until it is completely dissolved;
[0057] S2 was evacuated by a rotary evaporator and heated in a 60°C water bath to prepare a honeycomb-like film;
[0058] S3 prepare a solution of Lycium barbarum polysaccharide (2 mg / ml), take 5 ml as a hydration solution, and obtain nanoliposomes encapsulated with Lycium barbarum polysaccharide after passing through the membrane by ultrasonic for several minutes.
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