Essence lotion composition containing lipidosome with blackhead and acne removing effects and preparation method of essence lotion composition
A liposome and composition technology, applied in the field of daily chemicals, can solve the problems of difficulty in eradication, single component, and difficulty in effectively inhibiting blackheads, etc., and achieves the effects of increasing stability, reducing blackheads, and inhibiting the occurrence of blackheads
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Embodiment 1-3
[0066] An essence milk composition containing liposomes with the effect of removing blackheads is prepared into the essence milk for removing blackheads, and the content of its raw material composition ratio is shown in Table 1 below.
[0067] The raw material component distribution ratio (unit: mass %) of table 1 embodiment 1-3
[0068]
[0069] The preparation method of the essence milk composition containing blackhead-removing effect liposome of embodiment 1 comprises the following steps:
[0070] 1) Preparation of blackhead-removing effect liposome:
[0071] Accurately weigh 900mg of lecithin and 300mg of cholesterol, add 10mL of 95% ethanol into a beaker to fully dissolve; take 33mg of lentil seed extract, 33mg of Fucus serrata extract, 66mg of white willow bark extract, and 66mg of Ossia solstice extract Dissolve in 20mL phosphate buffer solution, place in a water bath at 50°C, and stir for later use; extract the above liposome solution with a syringe and inject it i...
Embodiment 1
[0089] Test sample: embodiment 1;
[0090] Test method: Use a third-party testing agency to test the safety. Select an area not exceeding 50mm 2 , with a suitable patch device with a depth of about 1mm, add about 0.02-0.025ml (g) of the test substance to the patch test device in a closed patch test method. Stick the spot tester on the curved side of the forearm of the subject, remove the test substance after 24 hours, observe the skin reaction at 0.5 hours, 24 hours, and 48 hours after removal, and record according to the skin reaction classification standard in > as a result.
[0091] Table 2 Patch test results
[0092]
[0093] Remarks: Skin reaction grading standard.
[0094] Level 0: Negative reaction;
[0095] Grade 1: Suspicious reaction; only faint erythema;
[0096] Grade 2: Weak positive reaction (erythema reaction); erythema, infiltration, edema, papules may be present;
[0097] Grade 3: strong positive reaction (herpes reaction); erythema, infiltration, ed...
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