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Cosmetic composition

A composition and extract technology, applied in the field of cosmetic compositions, can solve the problems of allergic reaction, instability, skin irritation and the like

Pending Publication Date: 2021-12-17
MARY KAY INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, moisturizers are not perfect
These humectant-related problems include: unpleasant tactile properties (such as heaviness, greasy or sticky feel), instability, skin irritation or insufficient moisturizing ability
However, many attempts were ineffective, only addressed one or a few undesired outcomes, or caused unacceptable side effects themselves, such as skin irritation or allergic reactions

Method used

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  • Cosmetic composition
  • Cosmetic composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0100] (material used)

[0101] The active ingredients in Table 1 were used to obtain the in vitro data mentioned below.

[0102] Table 1

[0103]

Embodiment 2

[0105] (clinical efficacy study)

[0106] It was surprisingly established that the combination of rosemary leaf extract, Botrytis longstemma extract, Morus berry extract and Porphyridium extract in clinical tests such as skin thickness measured by ultrasound, clinical scoring by experts and 2-D Photogrammetric reduction of skin laxity and improvement of skin hydration are effective. This data suggests that the combination of ingredients can act synergistically.

[0107] A. Skin thickness and skin laxity

[0108] A controlled clinical study was conducted to evaluate the efficacy of a facial lotion treatment product to provide antiaging benefits to the skin. The study is conducted over nine (9) weeks, the first week of which may be a "washout period" to ensure that the participant's prior product use does not affect the study, and the next eight (8) weeks may include test product use. Assessments of skin thickness and skin laxity were performed at baseline, weeks 2, 4, and 8 ...

Embodiment 3

[0115] (in vitro efficacy of ingredients)

[0116] Rosemary leaf extract, Botrytis longstemma extract, Mori fruit extract, and Porphyridium extract have been determined to increase skin antioxidant capacity (TEAC), increase collagen expression in skin, increase elastin in skin increased expression of laminin in the skin, inhibited MMP-1, inhibited MMP-3, inhibited MMP-9, inhibited pro-inflammatory cytokines (such as lipoxygenase, IL-6, Il-8, TNF-α or VEGF), inhibit the expression of elastase in the skin and / or increase the expression of fibronectin in the skin. A summary of the results is shown in Tables 2 to 9, and the methods used to determine the properties of the ingredients are provided below.

[0117] Table 2

[0118] (change in active expression)

[0119]

[0120] Antioxidant (AO) analysis: it was shown that rosemary leaf extract and mulberry extract inhibited (2,2'-Azidobis-[3-ethylbenzothiazolinesulfonate]) is oxidized to + to provide antioxidant capacity (T...

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Abstract

Methods of use and compositions useful for moisturizing skin, conditioning skin, reducing lines and wrinkles, evening skin tone, lightening skin tone, increasing skin radiance, elasticity, skin barrier function, and / or skin firmness, reducing photodamage, reducing sagging skin, increasing anti-oxidant capacity in skin, MMP-1, MMP-3, MMP-9, pro-inflammatory cytokines (e.g., lipoxygenase, IL-6, Il-8, TNF-alpha, or VEGF), and / or elastase expression in skin, and / or increasing collagen expression in skin, elastin expression in skin, laminin expression in skin, and / or fibronectin expression in skin are disclosed herein. The composition includes a combination of one or more of Rosmarinus officianalis leaf extract, Caulerpa lentillifera extract, Morus alba fruit extract, and Porphyridium cruentum extract.

Description

[0001] Cross References to Related Applications [0002] This application claims the benefit of priority to U.S. Provisional Patent Application Serial No. 63 / 039953, filed June 16, 2020, which is hereby incorporated by reference in its entirety. technical field [0003] The present invention generally relates to topical skin compositions and methods useful for conditioning skin, moisturizing skin, improving the evenness of skin tone, and / or reducing fine lines and wrinkles. In particular, the composition may comprise a plant-based material selected from the group consisting of Rosemary (Rosmarinus officianalis) leaf extract, Caulerpalentillifera (Caulerpalentillifera) extract, Morus alba fruit extract Extract or Porphyridium cruentum extract or any combination thereof. Background technique [0004] Many factors can alter or reduce the visual appearance, physical properties, or physiological functions of skin and tissues, including aging, chronic exposure to adverse environm...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/9722A61K8/9717A61Q19/00A61Q19/08
CPCA61K8/9789A61K8/9722A61K8/9717A61Q19/00A61Q19/08A61K2800/782A61K2800/5922A61K8/042A61K8/06A61K2236/331A61K2236/333A61Q19/007
Inventor 迈克尔·弗鲁肖尔吉赛·卡拉哈斯蒂大卫·甘
Owner MARY KAY INC
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