Preparation method of temperature-sensitive hydrogel and temperature-sensitive hydrogel product prepared by preparation method

Abstract

The invention relates to the field of new materials, in particular to a preparation method of temperature-sensitive hydrogel and a temperature-sensitive hydrogel product prepared by the preparation method. The preparation method comprises the following steps: putting chemically cross-linked polyvinyl alcohol hydrogel into a gallic acid solution for dipping treatment, and obtaining the temperature-sensitive polyvinyl alcohol hydrogel after dipping is finished. Polyvinyl alcohol hydrogel is soaked in a gallic acid solution for dipping treatment, hydrogel with temperature sensitivity is obtained, the mechanical strength of the hydrogel can change along with the temperature under the stimulation of a certain temperature, and the mechanical strength of the temperature-sensitive hydrogel is obviously higher than that of common polyvinyl alcohol hydrogel; besides, when the external temperature reaches the phase-change temperature of the hydrogel, the transparency of the hydrogel changes suddenly, namely, the opaque milk white is converted into a transparent state, the hydrogel can still recover to the initial state after the temperature is reduced, and the change process is reversible.

Description

technical field [0001] The invention belongs to the field of intelligent new materials, and in particular relates to a method for preparing a temperature-sensitive hydrogel and a temperature-sensitive hydrogel product prepared therefrom. Background technique [0002] Hydrogel is a kind of polymer material with a large amount of water and a three-dimensional network structure. It has important application prospects in the fields of joint lubrication, biological tissue engineering, and drug controlled release carriers. The smart hydrogel with temperature-sensitive properties can change its physical state after the external ambient temperature reaches the phase transition temperature of the hydrogel, and return to the original state after the temperature is restored, and the process is completely reversible. Contactless remote control can be realized by changing the ambient temperature, and it has potential applications in the field of injectable and biomimetic smart materials....

AI Technical Summary

Problems solved by technology

The chemical method needs to introduce a cross-linking agent, but the cross-linking agent is difficult to eliminate and has cytotoxicity; the freeze-thaw method is the most common physical method for preparing polyvinyl alcohol hydrogel, and the hydrogel obtained by this method has good elasticity. advantages, but it will turn into a solution at a higher temperature, and there are disadvantages such as long time-consuming, less swelling and opacity; the radiation method is a green method for synthesizing polyvinyl alcohol hydrogel, and the synthesis efficiency is fast. Good transparency, but poor toughness and easy to break

So far, there are few reports based on the development of temperature-sensitive polyvinyl alcohol-based hydrogels with good mechanical properties.

Images