Hypercrosslinked poly-porous resin adsorbent for blood perfusion and preparation method thereof

Abstract

The invention discloses a hyper-crosslinked poly-porous resin adsorbent for blood perfusion and a preparation method of the hyper-crosslinked poly-porous resin adsorbent. According to the preparation method disclosed by the invention, since the use of carcinogenic chloromethyl methyl ether is avoided in the preparation process, the problems of safety and environmental protection caused by the use of carcinogenic chloromethyl methyl ether in the traditional process are solved; according to the invention, a novel cross-linking agent system is adopted to realize post-crosslinking of the resin, and effective regulation and control of a specific pore structure and a specific surface area of the hypercrosslinked poly-porous resin adsorbent can be realized; the novel hypercrosslinked poly-porous resin adsorbent can be applied to the fields of blood perfusion environmental pollution treatment, chemical analysis, medicine separation and purification, catalysis, energy and the like.

Description

technical field [0001] The invention relates to the technical field of production technology of adsorbent resin in functional polymer materials, in particular to an ultrahigh cross-linked polyporous resin adsorbent for hemoperfusion and a preparation method thereof. Background technique [0002] Ultra-highly cross-linked polystyrene resin is a polymer adsorbent with a high degree of cross-linking, a complex internal structure, and a porous network structure. Compared with the traditional adsorbent activated carbon, ultra-high cross-linked polystyrene resin has higher specific surface area, rigid skeleton and stable physical and chemical properties, and also has the advantages of adjustable pore size structure and easy regeneration cycle. It is a polymer adsorbent with excellent performance, which is widely used in hemoperfusion technology, environmental pollution control, chemical analysis, separation and purification of drugs and other fields. Hemoperfusion technology is a...

AI Technical Summary

Problems solved by technology

[0003] However, there are still some problems in the production and use of ultra-highly cross-linked polystyrene resins. For example, the existing ultra-highly cross-linked polystyrene resins for hemoperfusion mainly use macroporous low-cross-linked polystyrene-divinylbenzene copolymers. Chloromethylation and Friedel-Crafts post-crosslinking; Among them, toxic and carcinogenic chloromethyl ether and other chemicals are used in the chloromethylation process. Due to its strong carcinogenicity and low boiling point and volatility, it is difficult for production operations It poses a great threat to the health of personnel, causes great pollution to the environment, and the preparation cost is high, thus affecting the sustainable development of the entire industry, and further technical optimization and improvement are needed; in addition, the prepared ultra-high cross-linked polyphenylene The vinyl resin structure also contains a certain amount of residual chloromethyl groups. During the storage and use of the hemoperfusion device, the residual chloromethyl groups will undergo side reactions such as hydrolysis, resulting in a decrease in pH value, and there are certain potential safety hazards in use.

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