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Traditional Chinese medicine composition for preventing and treating HPV (human papillomavirus) infection as well as extract, fermentation product and application of traditional Chinese medicine composition

A technology of composition and fermented product, applied in the directions of drug combination, antiviral agent, medical preparation containing active ingredients, etc., can solve the problems of pigmentation, heavy burden on the patient's heart, difficult treatment, etc., and achieves simple addition process, Good patient compliance and good compatibility

Active Publication Date: 2022-03-15
温州古木生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing methods of preventing and treating HPV infection usually use immunotherapy, interferon drugs, laser, freezing, external corrosive agents and surgical treatment, which has a certain risk of trauma infection, irritating and painful process, difficult to deal with special parts, heavy burden on patients, latent The virus is not easy to clear, and the recurrence rate is high.
Moreover, side effects such as pigmentation and skin scars often occur after physical intervention, which is difficult to meet the treatment needs of patients.

Method used

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  • Traditional Chinese medicine composition for preventing and treating HPV (human papillomavirus) infection as well as extract, fermentation product and application of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for preventing and treating HPV (human papillomavirus) infection as well as extract, fermentation product and application of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1: the preparation of Chinese medicine extract

[0025] Weigh 22g Banzhilian, 264g Kochia, 264g Caulis Spatholobus, 264g Curcuma, 264g Cortex Phellodendri, 264g Smilax, 22g Radix Radix, 22g Licorice, 22g Sophora, 22g Hedyotis diffusa, 22g Equisetum, after washing Put it in a decoction bag, put it in a decoction machine, add 15 times of pure water according to the weight of the traditional Chinese medicine composition, soak for 4 hours, then boil for 1.5 hours, and after standing for 4 hours, take the supernatant and use 1 micron Take the filtrate by plate and frame filtration, and concentrate it to about 7300g solution under vacuum negative pressure -0.07~-0.1MPa, 50~65°C to obtain the traditional Chinese medicine extract.

Embodiment 2

[0026] Embodiment 2: the preparation of Chinese medicine extract

[0027] Weigh 264g Scutellaria barbata, 22g Kochia chinensis, 22g Caulis Spatholobus, 22g Curcuma, 22g Cortex Phellodendri, 22g Smilax, 264g Radix Isatidis, 264g Licorice, 264g Sophora flavescens, 66g Hedyotis diffusa, 66g Equisetum, wash Put it in a decoction bag, put it in a decoction machine, add 15 times of pure water according to the weight of the traditional Chinese medicine composition, soak for 3 hours, then boil for 1.5 hours, and after standing for 2 hours, take the supernatant and use 1 micron Take the filtrate by plate and frame filtration, and concentrate it to about 6500g solution under vacuum negative pressure -0.07~-0.1MPa, 50~65°C to obtain the traditional Chinese medicine extract.

Embodiment 3

[0028] Embodiment 3: the preparation of Chinese medicine extract

[0029]Weigh 132g Scutellaria barbata, 44g Kochia chinensis, 44g Caulis Spatholobus, 44g Curcuma, 132g Cortex Phellodendri, 132g Smilax, 68g Radix Isatidis, 60g Licorice, 48g Sophora flavescens, 44g Hedyotis diffusa, 44g Equisetum, after washing Put it in a decoction bag, put it in a decoction machine, add 15 times pure water according to the weight of the traditional Chinese medicine composition, soak for 2 hours, then boil for 1 hour, and after standing for 1 hour, take the supernatant and use a 1 micron plate Take the filtrate by frame filtration, and concentrate it to about 4000g solution under vacuum negative pressure -0.07~-0.1MPa, 50~65°C to obtain the Chinese medicine extract.

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Abstract

The invention discloses a traditional Chinese medicine composition for preventing and treating HPV (human papillomavirus) infection as well as an extract, a fermentation product and application of the traditional Chinese medicine composition. Sculellaria barbata, fructus kochiae, caulis spatholobi, curcuma zedoary, cortex phellodendri, rhizoma smilacis glabrae, radix isatidis, liquorice, radix sophorae flavescentis, oldenlandia diffusa and equisetum hyemale are combined together according to the compatibility of monarch, minister, assistant and guide to obtain an extract and a fermentation product, and the extract and the fermentation product can be prepared into gels, suppositories, lotions, patches, emulsifiable paste and other dosage forms with the effect of preventing and treating HPV virus infection, can inhibit and kill pathogenic microorganisms, and can be used for preventing and treating HPV virus infection. The compound is used for resisting human papilloma virus. The composition has the effects of detoxifying, dispersing blood stasis and eliminating warts, can be used for preventing and treating cervical intraepithelial neoplasia, cervicitis, condyloma acuminatum, verruca plana, verruca vulgaris and other diseases caused by human papilloma virus infection, and is mild in effect, good in safety, convenient to use, good in patient compliance and suitable for personal care and wide clinical application.

Description

technical field [0001] The invention relates to the compatibility, extraction and application technology of a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for preventing and treating HPV virus infection, its extract, fermented product and application. Background technique [0002] Human papillomavirus (HPV) is a DNA virus that mainly infects epithelial cells, and humans are its only host. In recent years, the incidence of female reproductive tract infections caused by HPV has been increasing year by year. Persistent HPV infection is an important cause of the following diseases: 1. Cervical intraepithelial neoplasia and cervical cancer; hands, feet etc. Existing methods of preventing and treating HPV infection usually use immunotherapy, interferon drugs, laser, freezing, external corrosive agents and surgical treatment, which has a certain risk of trauma infection, irritating and painful process, difficult to deal with...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P31/20A61P31/12A61P31/04A61P31/02A61P31/10A61P35/00A61P29/00A61P17/04A61P37/08A61P15/00A61P17/12A61P17/02A61K8/9789A61K8/9794A61Q19/00
CPCA61K36/539A61K36/185A61K36/486A61K36/9066A61K36/756A61K36/90A61K36/896A61K36/195A61K36/315A61K36/484A61K36/489A61K36/748A61K36/11A61P31/20A61P31/12A61P31/04A61P31/02A61P31/10A61P35/00A61P29/00A61P17/04A61P37/08A61P15/00A61P17/12A61P17/02A61K8/9789A61K8/9794A61Q19/00A61K2236/331A61K2800/85A61K2300/00
Inventor 陈克陈赫予陈万胜
Owner 温州古木生物科技有限公司
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