High-fat meal formula for fat tolerance test
A technology of tolerance test and fat, which is applied in the field of high-fat meal tolerance test, can solve the problems of long taking time, authenticity of cover test, and no uniform standard of total calories, etc., and achieve the effect of stable test
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Embodiment 1
[0018] The first group was given 1500kcal of heat, and a total of 100 volunteers were recruited, 21 of whom experienced nausea, vomiting and other gastrointestinal discomfort reactions after eating a high-fat meal (15 of the 21 were less than 60kg in weight), and another 5 successfully passed the test. After eating a high-fat meal within 10 minutes, but diarrhea symptoms occurred at different times after the meal, these 26 subjects were unable to complete the follow-up blood collection due to the above discomfort symptoms, and quit the test midway, and finally a total of 74 subjects completed all oral fat Endurance test. The results are as follows
[0019] Table 1: 1500kcal test results
[0020]
[0021]
[0022] The second group subsequently recruited 100 volunteers to carry out the high-fat meal formula of the fat tolerance test of the present invention. All the subjects finished eating within 10 minutes, and 2 cases complained of mild nausea without dizziness and vom...
Embodiment 2
[0031] Subsequent comparisons of triglyceride levels at different time points before the test and after taking a high-fat meal showed that after the administration of 1500kcal calories, the serum triglyceride level of the test population increased significantly, and was still significantly higher than the fasting level 10 hours after the meal. And when the high-fat meal formula of the fat tolerance test of the present invention is given after the improvement, the change of serum triglyceride is relatively gentle, and it is basically reduced to the fasting level 8 hours after the meal, which suggests that a single administration of 1500kcal calories is too high, and the blood lipid load is overloaded. , the follow-up blood lipid value is less stable, and given the high-fat meal formula of the fat tolerance test of the present invention, the follow-up data is more stable.
[0032]
Embodiment 3
[0034] All subjects are grouped according to body weight, and it is found that giving 15000kcal heat is too large for the low body weight group load, causing postprandial blood lipids to significantly increase (Table 5), after the high-fat meal formula (Table 6) of the fat tolerance test of the present invention, The subjects in the low body weight group have good tolerance and stable postprandial reaction, suggesting that the high-fat meal total calories of the high-fat meal formula of the fat tolerance test of the present invention have a wider application range
[0035] Table 4
[0036]
[0037] table 5
[0038]
[0039] *: P<0.05; **: P<0.01.
[0040] It can be concluded from the above table that the high-fat meal prepared by the present invention can standardize the total calorie intake of the subjects, and further predict metabolic diseases by screening groups with reduced lipid tolerance, making up for the existing high-fat diet. Screening of patients with hyper...
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