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Molecularly imprinted material for efficiently adsorbing and removing fluoroquinolone antibiotics as well as preparation method and application of molecularly imprinted material

A technology of fluoroquinolones and molecular imprinting, applied in chemical instruments and methods, adsorption water/sewage treatment, other chemical processes, etc., can solve the problems of low adsorption capacity, limit the application of MIPs, poor recognition effect, etc., and achieve improved adsorption capacity , Improve recognition efficiency, improve the effect of selectivity

Active Publication Date: 2022-04-01
HENAN BUSINESS SCI RES INST +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, although MIPs can achieve selective recognition of targets in complex systems, their adsorption capacity is relatively low, and the recognition effect in aqueous phase is poor, which greatly limits the practical application of MIPs.

Method used

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  • Molecularly imprinted material for efficiently adsorbing and removing fluoroquinolone antibiotics as well as preparation method and application of molecularly imprinted material
  • Molecularly imprinted material for efficiently adsorbing and removing fluoroquinolone antibiotics as well as preparation method and application of molecularly imprinted material
  • Molecularly imprinted material for efficiently adsorbing and removing fluoroquinolone antibiotics as well as preparation method and application of molecularly imprinted material

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] A Molecularly Imprinted NH for Efficient Adsorption and Removal of Fluoroquinolone Antibiotics 2 -The preparation method of UiO-66 material, comprises the steps:

[0044] (1) Weigh 240mg of zirconium tetrachloride and 78mg of pipemidic acid in a 100mL Erlenmeyer flask, and add 60mL of N'N-dimethylformamide (DMF) into it, dissolve it by ultrasonic, and stir to make it pre- Reaction 1h, obtain A solution; Wherein, the mol ratio of zirconium tetrachloride and pipemidic acid is 4: 1;

[0045] (2) Add 94 mg of 2-aminoterephthalic acid to solution A, dissolve it by ultrasonic, and stir for 30 minutes to obtain solution B;

[0046] (3) Transfer the B solution to a 100mL polytetrafluoroethylene lined bottle, then transfer it to a 100mL reaction kettle, place it in a blast drying oven, react at 120°C for 48h, cool it down to room temperature naturally, and take the reaction solution Centrifuge at 1000rpm for 15min, and discard the supernatant to obtain the intermediate product...

Embodiment 2

[0049] A Molecularly Imprinted NH for Efficient Adsorption and Removal of Fluoroquinolone Antibiotics 2 -The content of the preparation method of the UiO-66 material is basically the same as that of Example 1, except that the amount of pipemidic acid described in step (1) is 124.8 mg, wherein zirconium tetrachloride and pipemidic acid The molar ratio is 5:2.

Embodiment 3

[0051] A Molecularly Imprinted NH for Efficient Adsorption and Removal of Fluoroquinolone Antibiotics 2 -The content of the preparation method of the UiO-66 material is basically the same as that of Example 1, except that the amount of pipemidic acid described in step (1) is 156 mg, wherein the amount of zirconium tetrachloride and pipemidic acid The molar ratio is 2:1.

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Abstract

The invention belongs to the technical field of novel environment-friendly materials, and discloses a preparation method of a molecularly imprinted material for efficiently adsorbing and removing fluoroquinolone antibiotics, which comprises the following steps: firstly, respectively taking pipemidic acid, zirconium tetrachloride and 2-aminoterephthalic acid as template molecules, metal salts and organic ligands; the preparation method comprises the following steps: synthesizing a molecularly imprinted polymer with NH2-UiO-66 as a substrate by using a solvothermal one-pot method; then, a proper solvent is selected to elute the template molecules, and the molecularly imprinted NH2-UiO-66 material is prepared. According to the invention, pipemidic acid is used as a virtual template molecule, the molecularly imprinted NH2-UiO-66 material with specific adsorption performance is provided, and the material has good adsorption performance on fluoroquinolone antibiotics, can realize selective adsorption removal, and has good application prospects. The problems that a traditional molecularly imprinted polymer is low in adsorption capacity and poor in specific recognition capacity in a polar environment are effectively solved, and the problem that the adsorption removal effect of a molecularly imprinted material is affected by leakage of template molecules is effectively solved by using the virtual template.

Description

technical field [0001] The invention belongs to the field of new environmental protection materials, and in particular relates to a molecularly imprinted material for efficiently adsorbing and removing fluoroquinolone antibiotics, a preparation method and application thereof. Background technique [0002] In recent years, due to the extensive use and unreasonable discharge of antibiotics, they have been frequently detected in the environment, resulting in varying degrees of pollution, which has aroused widespread public concern. Long-term contact or exposure to antibiotic-contaminated environments can cause allergic reactions and potential "three-cause" (carcinogenic, teratogenic, and mutagenic) effects, induce the generation and spread of resistance genes in the body, and the formation of drug-resistant bacteria. pose a serious threat to human health. Quinolones antibiotics are a class of general-purpose drugs for humans and animals. Because of their broad antibacterial sp...

Claims

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Application Information

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IPC IPC(8): B01J20/22B01J20/26B01J20/30C02F1/28C02F101/30C02F101/34C02F101/36C02F101/38
Inventor 万丽斌高火亮陈满堂高海东刘晓高树财闫格杜瑞
Owner HENAN BUSINESS SCI RES INST
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