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Traditional Chinese medicine composition for treating wind-cold obstruction nerve root type cervical spondylosis, preparation and application

A technology of nerve root type and composition, which is applied in the field of traditional Chinese medicine composition and preparation, can solve problems such as prolonged treatment time, unsatisfactory function recovery effect, and poor treatment effect, so as to relieve pain symptoms, relieve numbness symptoms, and relieve muscle pain. The effect of tension

Active Publication Date: 2022-04-22
云南省中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the commonly used drugs in clinical practice are not effective in the treatment of such diseases, resulting in prolonged treatment time for patients and unsatisfactory functional recovery.

Method used

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  • Traditional Chinese medicine composition for treating wind-cold obstruction nerve root type cervical spondylosis, preparation and application
  • Traditional Chinese medicine composition for treating wind-cold obstruction nerve root type cervical spondylosis, preparation and application
  • Traditional Chinese medicine composition for treating wind-cold obstruction nerve root type cervical spondylosis, preparation and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Prescription: notopterygium 20g, kudzu root 30g, cassia twig 30g, mulberry branch 30g, chuanxiong 15g, rehmannia glutinosa 15g, angelica 15g, red peony root 10g, asarum 3g, clematis 10g, salvia miltiorrhiza 20g, centipede 1, gastrodia elata 15g, Zhiren 20g, Zhiyuanzhi 15g. Put all the medicines in a pot, add water to cover the medicines by 2~3cm, soak for 30 minutes, first boil on high heat, then fry on low heat for 30 minutes, take about 150ml of juice; add appropriate amount of water again, boil on high heat, and fry on low heat for 10 minutes, Take about 150ml of the juice, and combine the broth to obtain a decoction.

Embodiment 2

[0036] Prescription: notopterygium 20g, kudzu root 40g, cassia twig 40g, mulberry branch 40g, chuanxiong 30g, rehmannia glutinosa 30g, angelica 20g, red peony root 10g, asarum 9g, clematis 20g, salvia miltiorrhiza 25g, centipede 2, gastrodia elata 30g, Zhiren 30g, Zhiyuanzhi 30g. Add water to decoct each medicinal flavor of the prescription according to the weight ratio of 1:6, add water and decoct 1~3 times, each time for 50 minutes, and combine the decoction liquid; concentrate the obtained decoction liquid at 70°C, -0.02~-0.06MPa vacuum degree to thicken Paste, the thick paste has a density of 1.35g / ml at 60°C; the thick paste is dried at 65°C under a vacuum of -0.02~-0.06MPa to form a dry paste, and the dry paste is crushed and passed through a 100-mesh sieve to obtain a mixed dry paste powder. Mix 20g of sucrose evenly, add an appropriate amount of 75% ethanol, wet granulate, and obtain granules after drying.

Embodiment 3

[0038] Prescription: Notopterygium 20g, Pueraria 35g, Guizhi 35g, Sangzhi 35g, Chuanxiong 20g, Rehmannia glutinosa 20g, Angelica 30g, Radix Paeoniae Rubra 15g, Asarum 6g, Clematis 15g, Salvia miltiorrhiza 30g, Centipede 2, Gastrodia elata 20g, Zhiren 25g, Zhiyuanzhi 20g. Weigh each medicinal herb in the formula according to the formula, add water to decoct 1 to 3 times according to the weight ratio of medicine to water 1:9, each time for 60 minutes, and combine the decoction liquid; store the decoction liquid at 70°C, -0.02~ Concentrate into a thick paste under vacuum of -0.06MPa, and the density of the thick paste is 1.20g / ml at 50°C; dry the thick paste at 705°C under a vacuum of -0.02~-0.06MPa to form a dry paste, crush the dry paste and pass through 100 Mesh sieve to obtain the mixed dry cream powder, and water pills to obtain pills.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating wind-cold blocking nerve root type cervical spondylosis, a preparation and application. The traditional Chinese medicine composition is prepared from the following components by weight: 15-20g of notopterygium root, 30-40g of kudzuvine root, 30-40g of cassia twig, 3-9g of asarum, 30-40g of mulberry twig, 15-30g of angelica sinensis, 15-30g of ligusticum wallichii, 20-30g of salvia miltiorrhiza, 10-10g of red paeony root, 15-30g of prepared rehmannia root, 10-20g of radix clematidis, 1 centipede, 15-30g of gastrodia elata, 20-30g of fructus alpiniae oxyphyllae and 15-30g of roasted polygala tenuifolia. The traditional Chinese medicine composition is used for treating wind-cold collateral blocking type cervical spondylosis by simultaneously treating three yang and considering exterior and interior so as to relieve discomfort symptoms such as soreness, numbness, swelling pain and the like of shoulders and necks. The traditional Chinese medicine composition is precise and appropriate in compatibility, mild and clear in medication, and capable of effectively relieving shoulder and neck pain symptoms, relieving numbness symptoms of upper limbs, shoulders and necks, relieving muscle tension state, tonifying kidney essence and consolidating the root of congenital. The two groups have certain advantages in improving the symptoms of the wind-cold collateral-blocking type cervical spondylosis. The traditional Chinese medicine symptom treatment effect total effective rate treatment group is 83.87%, the traditional Chinese medicine symptom treatment effect total effective rate treatment group is 65.51%, and the traditional Chinese medicine symptom treatment effect of the traditional Chinese medicine composition is superior to that of the control group in the aspect of the traditional Chinese medicine symptom treatment effect.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine compositions and preparations, and in particular relates to a traditional Chinese medicine composition, preparation and application for treating cervical spondylotic radiculopathy caused by wind-cold blocking collaterals. Background technique [0002] Cervical spondylosis refers to the spinal cord, nerve, and blood vessel damage caused by degenerative disc disease and its secondary changes, as well as the corresponding symptoms and signs. At present, its etiology and pathogenesis are not completely clear in Western medicine, and it is generally believed to be the result of multiple factors acting together. Cervical spondylosis belongs to the category of arthralgia, wilt, and vertigo in traditional Chinese medicine. With the popularization of electronic products and changes in work and lifestyle, such as long-term office work, playing with mobile phones, and reading, the incide...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9062A61K36/9068A61K9/16A61K9/20A61K9/08A61P19/00A61K35/648
CPCA61K36/237A61K36/488A61K36/54A61K36/605A61K36/236A61K36/804A61K36/232A61K36/71A61K36/65A61K36/268A61K36/716A61K36/537A61K35/648A61K36/8988A61K36/9062A61K36/69A61K36/714A61K36/9068A61K36/284A61K36/8994A61K36/481A61K36/238A61K9/0095A61K9/1617A61K9/2013A61P19/00A61K2236/331A61K2236/39A61K2236/53A61K2236/51A61K2300/00Y02A50/30
Inventor 邵水艳陈涛李川万青魏庆中刘盾邹成松张茜郑远志
Owner 云南省中医医院
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