Drug-loaded double-layer spinous process balloon catheter

A spinous process balloon and drug-loading technology, which is applied in balloon-shaped catheters, medical science, surgery, etc., can solve the problems of drug loss, increase the complexity of doctors' operations, increase the time of filling and fitting, and increase the ischemic necrosis of the distal myocardium. , to achieve the effect of strengthening the release effect, reducing the risk of surgery, and improving the efficiency of surgery

Active Publication Date: 2022-07-08
WEST CHINA HOSPITAL SICHUAN UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, when the conventional drug-coated balloon is delivered to the target lesion site, repeated "filling-withdrawing-filling-withdrawing" operations are required to complete the release of the drug. For elderly patients, too long filling and fitting time will increase the risk of distal myocardial ischemic necrosis, and too short filling time will make the drug treatment effect not good. , and multiple repeated fillings will cause a large amount of drug loss, increase the complexity of the doctor's operation, and increase the risk of accidental rupture of the balloon

Method used

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  • Drug-loaded double-layer spinous process balloon catheter
  • Drug-loaded double-layer spinous process balloon catheter
  • Drug-loaded double-layer spinous process balloon catheter

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] Embodiment 1 provides a drug-loaded double-layer spinous process balloon catheter to solve the problems existing in the prior art. refer to Figure 1-Figure 7 In a preferred embodiment, the above-mentioned double-layer spinous process balloon catheter mainly comprises an inner tube 7, an outer tube 2, an inner balloon 8, an outer balloon 3, a developing ring 10, a hypotube 12 and a coaxial arrangement. Catheter adapter 14 .

[0059] like figure 1 , the outer tube 2 and the inner tube 7 are fixedly connected at the distal end, and the two together form a balloon catheter. The proximal end of the outer tube 2 is connected with a catheter seat 14 for injecting contrast agents, and the distal end of the outer tube 2 is provided with an inflatable Or the collapsed inner balloon 8, the annular cavity between the outer tube 2 and the inner tube 7 constitutes the liquid injection channel of the inner balloon 8, the outer balloon 3 is sleeved outside the inner balloon 8, and t...

Embodiment 2

[0076] refer to Figure 8 , this embodiment provides a preferred structure of the drug-loaded cutting balloon catheter.

[0077] In this embodiment, the balloon catheter includes an inner tube 7 , an outer tube 2 , an inner balloon 8 , an outer balloon 3 , a developing ring 10 , a hypotube 12 and a catheter holder 14 , which is the same as the structure disclosed in Embodiment 1. The difference is that in this embodiment, the shapes of the first spinous process 4 and the second spinous process 9 are changed.

[0078] Since the structure of the double-layer balloon will affect the compliance of the balloon catheter to a certain extent, in order to ensure that the first spinous process 4 and the second spinous process 9 can be axially and / radially compressed, crimped and Folding, preferably, the first spinous process 4 spirally surrounds the surface of the outer balloon 3 , and the second spinous process 9 spirals spirally surrounds the surface of the inner balloon 8 .

[0079...

Embodiment 3

[0084] This embodiment provides a preferred structure of the drug-loaded cutting balloon catheter. In this embodiment, the balloon catheter includes an inner tube 7 , an outer tube 2 , an inner balloon 8 , an outer balloon 3 , a developing ring 10 , a hypotube 12 and a catheter holder 14 , which is the same as that in Embodiment 1 or Embodiment 2. The difference between the disclosed structures is that in this embodiment, the elastic modulus / expansion coefficient of different positions on the inner balloon 8 is different, so that different second spinous processes 9 are expanded in turn, and at the same time, different first spinous processes 4 are expanded. Expanding in sequence, different first spinous processes 4 are selectively provided with or not provided with a drug-carrying cavity 5 .

[0085] Preferably, the regions to which different second spinous processes 9 are bonded on the inner balloon 8 are pressed with different materials to ensure that the regions to which d...

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Abstract

The main structure of the drug-loaded double-layer spinous process balloon catheter comprises an inner balloon and an outer balloon arranged on the outer side of the inner balloon in a sleeving mode, spinous processes are arranged on the outer surface of the inner balloon and the outer surface of the outer balloon, and a second spinous process on the inner balloon and a first spinous process on the outer balloon are arranged at the corresponding positions; particularly, a medicine carrying cavity used for containing medicine is further formed in the first spinous process, and a plurality of medicine outlet holes are formed in the surface of the first spinous process. A contrast agent is injected into the inner balloon to enable the inner balloon to be full, meanwhile, the outer balloon and the first spinous process on the outer balloon can be expanded under radial supporting force and then embedded into plaques at the lesion position of the inner wall of the blood vessel, the second spinous process arranged on the inner balloon can extrude the corresponding first spinous process on the outer balloon, and the second spinous process on the inner balloon can extrude the plaques at the lesion position of the inner wall of the blood vessel. Therefore, the medicine contained in the medicine carrying cavity can be released, the release effect of the medicine is enhanced, and the operation risk is reduced.

Description

technical field [0001] The invention relates to the field of interventional medical instruments, in particular to a drug-loaded double-layer spinous process balloon catheter. Background technique [0002] PCI is the abbreviation of percutaneous coronary intervention, which refers to the treatment of improving myocardial blood perfusion by transcardiac catheter technique to dredge stenotic or even occluded coronary lumen. Its technical classification mainly includes percutaneous coronary balloon angioplasty, coronary stenting, cutting balloon into the line and coronary thrombus aspiration and so on. With the increase in the incidence of coronary heart disease and the development of PCI technology, the number of PCI operations in China has increased rapidly in recent years. In clinical practice, drug-eluting stents (DES) are still the dominant angioplasty. It will remain in the blood vessel forever. Although the technology is very mature and very safe, there is still a long-t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M25/10A61B17/22
CPCA61M25/1002A61M25/1006A61M25/1011A61B17/22A61M2025/105A61M2025/1075A61M2025/1079A61M2025/109A61B2017/22065A61B2017/22081A61M2025/1013A61M25/104A61M2025/1086
Inventor 冯沅陈茂徐亚鹏杨夏燕虞奇峰
Owner WEST CHINA HOSPITAL SICHUAN UNIV
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