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Porous artificial vertebral body and preparation method thereof

An artificial and vertebral body technology, applied in the field of porous artificial vertebral body and its preparation, can solve the problems of bone resorption, low porosity, mechanical properties and natural bone mismatch.

Pending Publication Date: 2022-07-15
深圳大洲医学科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Existing artificial vertebral body, such as patent CN106923941A, is a kind of artificial vertebral body integrated with personalized plates based on 3D printing, but only one side of it is a void structure, the porosity is low, and only limited bone ingrowth is allowed; and this structure The elastic modulus is much higher than that of human bone, and the mechanical properties do not match with natural bone, which will cause stress shielding phenomenon, resulting in bone resorption and osteolysis

Method used

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  • Porous artificial vertebral body and preparation method thereof
  • Porous artificial vertebral body and preparation method thereof
  • Porous artificial vertebral body and preparation method thereof

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preparation example Construction

[0057] The present invention provides a method for preparing the above-mentioned porous artificial vertebral body, comprising the following steps:

[0058] Porous artificial vertebral bodies are fabricated by additive manufacturing.

[0059] In the present invention, the additive manufacturing method is preferably a powder bed laser melting method or a powder bed electron beam melting method.

[0060] In the present invention, the parameters of the powder laser melting method preferably include:

[0061] The laser power is 150-350W, more preferably 200-300W;

[0062] The scanning speed is 100-500 mm / s, more preferably 200-400 mm / s;

[0063] The scanning line pitch is 0.05 to 0.15 mm, more preferably 0.08 to 0.12 mm:

[0064] The substrate temperature is 100-200°C, more preferably 120-160°C;

[0065] The slice layer thickness is 0.02 to 0.05 mm, more preferably 0.03 to 0.04 mm.

[0066] In the present invention, the parameters of the powder bed electron beam melting method...

Embodiment 1

[0079] prepared by powder laser melting Figures 1 to 4 For the porous artificial vertebral body of the structure shown, the specific operation steps are:

[0080] Import the 3D model file of the porous artificial vertebral body into the powder bed laser melting additive manufacturing equipment, and pre-lay a sufficient amount of medical pure tantalum metal powder in the additive manufacturing equipment, and select appropriate process parameters (specifically: layer thickness 0.03mm, The substrate temperature is 100°C, the laser power is 250W, the scanning speed is 200mm / S, and the scanning line spacing is 0.09mm).

[0081] Take out the sintered workpiece, and perform cleaning, wire cutting, de-supporting, sandblasting, ultrasonic cleaning, heat treatment, final cleaning, drying, and sterilization in sequence.

[0082] The obtained porous artificial vertebral body is composed of a porous main body structure 1 and a solid reinforcing rib 3. The porous main body structure 1 has...

Embodiment 2

[0097] prepared by powder electron beam melting Figures 1 to 4 For the porous artificial vertebral body of the structure shown, the specific operation steps are:

[0098] Import the 3D model file of the porous artificial vertebral body into the powder bed electron beam fusion additive manufacturing equipment. In the additive manufacturing equipment, a sufficient amount of tantalum zirconium alloy powder is pre-laid, and appropriate process parameters are selected. The powder material is sintered into the shape of the imported model.

[0099] The process parameters are:

[0100] The preheating temperature is 1000℃, the scanning current is 10mA, and the scanning speed is 1.0×10 5 mm / s, slice thickness is 40um.

[0101] Take out the sintered workpiece, and perform sandblasting, ultrasonic cleaning, drying and sterilization in sequence.

[0102]The obtained porous artificial vertebral body is composed of a porous main body structure 1 and a solid reinforcing rib 3. The porous...

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Abstract

The invention provides a porous artificial vertebral body and a preparation method thereof, and belongs to the technical field of biomedical materials. The porous artificial vertebral body provided by the invention comprises a porous main body structure (1), wherein the porosity of the porous main body structure is 50-80%; the porous main body structure (1) is provided with an upper surface, a lower surface and four side surfaces; a hollow bone grafting channel (2) is arranged in the porous main body structure (1) and penetrates through the upper surface and the lower surface of the porous main body structure (1); the solid reinforcing ribs (3) vertically penetrate through the upper surface and the lower surface of the porous main body structure (1). The porous artificial vertebral body provided by the invention is high in porosity, so that fusion and ingrowth of new bone tissues are facilitated; the porous main body structure (1) serves as a main body of the artificial vertebral body, the solid reinforcing ribs (3) are arranged in the porous main body structure (1), and the mechanical property of the porous artificial vertebral body can be matched with that of a natural bone while the strength of the porous artificial vertebral body is guaranteed.

Description

technical field [0001] The invention relates to the technical field of biomedical materials, in particular to a porous artificial vertebral body and a preparation method thereof. Background technique [0002] Trauma, disease, or congenital factors can lead to a variety of spinal injuries and deformities that can ultimately lead to impaired vertebral function. Spinal injuries may be traumatic, such as vertebral fractures, or nontraumatic deformities caused by tumors or vertebral bone degeneration. In the treatment of most spinal injuries, anterior reconstruction of the spine is required, most commonly with total resection of the damaged vertebral body. In a typical anterior approach, partial or total surgical resection of the vertebral body and two adjacent discs is performed, followed by artificial vertebral body replacement in the space created by the removal of the vertebral body and discs. [0003] Existing artificial vertebral bodies such as patent CN106923941A, a 3D p...

Claims

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Application Information

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IPC IPC(8): A61F2/44A61F2/30
CPCA61F2/44A61F2/30771A61F2/30942A61F2002/30772A61F2002/3093A61F2002/30985
Inventor 张大琛杨景周陈海深杨景浩张树培
Owner 深圳大洲医学科技有限公司