Probiotic carrier, probiotic drops and preparation methods of probiotic carrier and probiotic drops

A technology of probiotics and carriers, applied in the field of probiotics, can solve the problems of reducing the circulation range of convenient products, reducing the decay rate of probiotics, and rapidly decreasing the activity of probiotics, and achieving good practical production feasibility and good food safety. , The effect of excellent complex dispersion performance

Pending Publication Date: 2022-08-05
BIOSTIME GUANGZHOU HEALTH PROD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

According to the SiO2 released by the European Food Safety Authority in 2008 2 Safety assessment as a food additive shows that SiO cannot be identified due to insufficient evidence 2 ADI value (Acceptable Daily Intake), so SiO was added 2 drop products have potential unknown safety risks
Furthermore, due to the high water activity of the oil, the probiotic activity decreases rapidly
In order to reduce the attenuation rate of probiotics, the storage conditions of probiotic drops products must be set below 4°C, which reduces the convenience of use and the circulation range of products

Method used

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  • Probiotic carrier, probiotic drops and preparation methods of probiotic carrier and probiotic drops
  • Probiotic carrier, probiotic drops and preparation methods of probiotic carrier and probiotic drops
  • Probiotic carrier, probiotic drops and preparation methods of probiotic carrier and probiotic drops

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] A probiotic bacteria drop is prepared from the formula in Table 1. The probiotic bacteria drop of Example 1 has good stability and excellent multi-dispersion performance, and can simultaneously improve infantile diarrhea and relieve infantile constipation.

[0051] The formula table of table 1 embodiment 1 probiotic bacteria drops

[0052]

[0053]

[0054] The probiotic bacteria drops of embodiment 1 are prepared according to the following method:

[0055] Bacteria thawing: Place Bifidobacterium breve M-16V bacterial powder and Bifidobacterium infantis R0033 bacterial powder at a temperature of 18°C ​​and thaw for 48 hours. After thawing, dry the water droplets on the aluminum foil bag with an alcohol cloth and set aside.

[0056] Bifidobacterium breve M-16V, Bifidobacterium infantis R0033, mono- and diglyceride fatty acid esters and MCT oil were weighed according to the formula amount.

[0057] Pass Bifidobacterium breve M-16V bacterial powder and Bifidobacter...

Embodiment 2

[0062] A probiotic bacteria drop is prepared from the formula in Table 2. The probiotic bacteria drop of Example 2 has good stability and excellent complex dispersion performance, and can simultaneously improve infant diarrhea and relieve infant constipation.

[0063] The formula table of table 2 embodiment 2 probiotic bacteria drops

[0064] Ingredients weight percentage Bifidobacterium infantis R0033 5％ Bifidobacterium breve M-16V 10％ Medium Chain Triglycerides (MCTs) 83.5％ Mono and diglycerol fatty acid esters 1.5％

[0065] The probiotic bacteria drops of embodiment 2 are prepared according to the following method:

[0066] Bacteria thawing: Place the Bifidobacterium breve M-16V bacterial powder and Bifidobacterium infantis R0033 bacterial powder at a temperature of 26°C and thaw for 12 hours. After thawing, dry the water droplets on the aluminum foil bag with an alcohol cloth and set aside.

[0067] Bifidobacterium breve M-16V, Bifi...

Embodiment 3

[0073] A probiotic bacteria drop is prepared from the formula in Table 3. The probiotic bacteria drop of Example 3 has good stability and excellent multi-dispersion performance, and can simultaneously improve infant diarrhea and relieve infant constipation.

[0074] The formula table of table 3 embodiment 3 probiotic bacteria drops

[0075] Ingredients weight percentage Bifidobacterium infantis R0033 3.0％ Bifidobacterium breve M-16V 7.0％ Medium Chain Triglycerides (MCTs) 89.0％ Mono and diglycerol fatty acid esters 1.0％

[0076] The probiotic bacteria drops of embodiment 3 are prepared according to the following method:

[0077] Bacteria thawing: Place Bifidobacterium breve M-16V bacterial powder and Bifidobacterium infantis R0033 bacterial powder at a temperature of 22°C and thaw for 30 hours. After thawing, dry the water droplets on the aluminum foil bag with an alcohol cloth and set aside.

[0078] Bifidobacterium breve M-16V, Bifidob...

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Abstract

The invention discloses a probiotic carrier, a probiotic drop and preparation methods of the probiotic carrier and the probiotic drop. The probiotic carrier comprises the following components in parts by weight: 83.5-93.5 parts of medium-chain triglyceride and 0.5-1.5 parts of mono-and diglycerol fatty acid esters. The probiotic drops are prepared from the following components in percentage by weight: 1 to 5 percent of bifidobacterium infantis, 5 to 10 percent of bifidobacterium breve, 83.5 to 93.5 percent of medium-chain triglyceride and 0.5 to 1.5 percent of mono-and diglycerol fatty acid ester. The probiotic carrier provided by the invention has good edible safety, and can ensure excellent re-dispersion performance of the product after the probiotic powder is added. The probiotic drop provided by the invention is suitable for infants, does not need to be refrigerated, can be stored for a long time at the temperature of lower than 40 DEG C, and has high survival rate of probiotics. The preparation method of the probiotic drops provided by the invention is simple, convenient and rapid, the quality is easy to control, and the preparation method has good practical production feasibility.

Description

technical field [0001] The invention relates to the technical field of probiotics, in particular to a probiotics carrier, a probiotics drop and a preparation method thereof. Background technique [0002] Probiotics are live microorganisms that, when administered to the host in appropriate amounts, confer health benefits to the host. Because probiotics can bring health benefits to people, they are widely studied and applied as functional food raw materials. According to multiple preclinical and clinical studies, probiotic strains are able to trigger the immune system and relieve symptoms of various diseases, including regulating gut health, enhancing immunity, reducing the risk of cardiovascular disease, relieving allergies, improving colic, and more. At the same time, clinical research on probiotics is strain-specific, and the probiotic functions of different strains of the same species are not exactly the same. For example, clinical studies show that Bifidobacterium lactis...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K47/14A61K9/14A61K35/745A61P1/10A61P1/12
CPCA61K35/745A61K9/145A61K47/14A61K9/0095A61P1/12A61P1/10A61K2300/00Y02A50/30
Inventor 赵飞胡瑞标彭倩
Owner BIOSTIME GUANGZHOU HEALTH PROD
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