Method for improving assisted reproduction success rate, verification method and verification system

Abstract

The invention discloses a method for improving the success rate of assisted reproduction and a verification method and system.The method for improving the success rate of assisted reproduction comprises the steps that a plurality of culture solutions obtained after blastocyst culture are obtained, and free DNA of embryos on the sixth day to the seventh day is extracted from the culture solutions; the free DNA is used for carrying out embryo uploidy analysis, uploidy scores of all embryos are compared, priority ranking is carried out according to the uploidy scores of the embryos, and the embryos with high priorities have high development potential; according to the method, endometrial receptivity analysis is conducted through an endometrial sample, the receptivity of the endometrial is judged, a corresponding transplantation strategy is made according to a result, the receptivity comprises a receptivity period and a non-receptivity period, and the corresponding transplantation strategy is that the endometrial in the receptivity period state is in a transplantable state, and the endometrial in the non-receptivity period state is in a non-transplantable state; the transplantation time of the endometrium in the non-receptive state is adjusted to reach a transplantable state. The technical scheme can effectively improve the success rate of assisted reproduction.

Description

technical field [0001] The invention relates to the technical field of assisted reproduction, in particular to a method, a verification method and a system for improving the success rate of assisted reproduction. Background technique [0002] Polycystic ovary syndrome (PCOS) is a common gynecological endocrine disease with an incidence of 5%-10%, and is one of the important causes of female infertility. With the development of assisted reproductive technology (ART) in recent years, common assisted reproductive procedures include: controlled ovulation induction, in vitro fertilization, blastocyst culture, blastocyst cryopreservation, embryo recovery and transfer, etc. The ovulation induction program can achieve a high cumulative ovulation rate, but there are still low implantation rates and high miscarriage rates, resulting in a low success rate of assisted reproduction. SUMMARY OF THE INVENTION [0003] In view of the above problems, the present invention provides a metho...

AI Technical Summary

Problems solved by technology

With the development of assisted reproductive technology (assisted reproductive technique, ART) in recent years, common assisted reproductive procedures include: controlled ovulation induction, in vitro fertilization, blastocyst culture, blastocyst cryopreservation, embryo resuscitation and transplantation, etc. The ovulation induction program can achieve a higher cumulative ovulation rate, but there are still low implantation rates and high miscarriage rates, resulting in a low success rate of assisted reproduction

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