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Cough asthma stoppig drip pill and its preparation method

A technology of dripping pills and Manshanhong, applied in pill delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems that are not conducive to improving the ability of patients to seek medical treatment, the first-pass bioavailability of the liver and intestines, and the overall health level and other issues, to achieve the effects that are conducive to labor protection and environmental protection, improve bioavailability, and drug safety

Inactive Publication Date: 2007-05-23
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
In addition, conventional oral dosage forms, such as granules, tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and also Will cause some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

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Embodiment Construction

[0031] Now with several groups of specific examples, the preparation method of the Zhikechuan dripping pills of the present invention will be further described.

[0032] [Group 1: Trials with a single substrate]

[0033] 1. Preparation of medicinal extracts: According to the [Appendix], the dry extract powders containing the active ingredients of three traditional Chinese medicines, such as Manshanhong, Campanulaceae, and Licorice, were first prepared for use;

[0034] 2. Substrate: polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, polyoxyl 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0035] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0036] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain Zhikechuan Dropping Pills of different specifications...

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PUM

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Abstract

A Chinese medicine in the form of dripping pill for treating bronchitis, bronchitis asthma, viscose more sputum, cold cough, etc is prepared from dahurian rhododendron leaf, platycodon root, liquorice root and medicinal carrier. Its preparing process is also disclosed.

Description

technical field [0001] The present invention relates to a kind of medicine composition that has the effects of relieving cough, relieving asthma and eliminating phlegm, and is used for the treatment of diseases such as bronchitis, bronchial wheezing, excessive phlegm, thick phlegm, common cold and cough, lung abscess and vomiting of pus, chest fullness and hypochondriac pain, etc. The invention relates to an oral preparation of a pharmaceutical composition prepared by using extracts of active ingredients of three traditional Chinese medicines, such as Manshanhong, Campanulaceae, and Licorice, as raw materials. Background technique [0002] According to the ministerial drug standard WS 3 - Zhikechuan granule prepared by the preparation method given in B-0702-91 is a cough-relieving, asthma-relieving, and expectorant-relieving granule, which is used for bronchitis, bronchial wheezing, excessive phlegm, thick phlegm, cold and cough, The oral preparation for the treatment of lu...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/484A61K36/45A61K36/34A61P11/00A61P11/14
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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