Quick disintegrated tablet or oral cavity disintegrated tablet containing L-glutamic acid and azulene sodium sulfonate and making method thereof
A technology for sodium azulene sulfonate and its manufacturing method, which can be applied to medical preparations containing active ingredients, pill delivery, pharmaceutical formulations, etc., and can solve the problems of sodium azulene sulfonate, such as inhomogeneous dispersion, irritation, and tablet fragmentation
Inactive Publication Date: 2003-05-21
KYOWA HAKKO KIRIN CO LTD +1
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Abstract
Quick disintegrated tablet or oral cavity disintegrated tablet containing L-glutamic acid and azulene sodium sulfonate and making method thereof are peovided. The method includes that: granulating substance is produced by pelleting the mixture of L-glutamic acid and azulene sodium sulfonate using lactose-containing water solution as adhesive and drying it, then the tablet is produced by compression moulding. The tablet is quickly disintegrable in contact with the spit in the the oral cavity without water, while it has high strength.
Application Domain
Organic active ingredientsDigestive system +1
Technology Topic
Aqueous solutionAdhesive +5
Examples
- Experimental program(3)
- Comparison scheme(3)
- Effect test(1)
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