Adsorbent for endocrine disruptors and foods and drinks containing the same

Inactive Publication Date: 2003-07-09
YAKULT HONSHA KK
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] However, there have been no reports of microorganisms absorbing endocrine-disrupting chemicals in the intestinal tract of humans and animals and inhibiting the in vivo absorption of the chemicals

Method used

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  • Adsorbent for endocrine disruptors and foods and drinks containing the same
  • Adsorbent for endocrine disruptors and foods and drinks containing the same
  • Adsorbent for endocrine disruptors and foods and drinks containing the same

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0124] The sample was prepared by the same method as in (1)(a) above. (b) Prepare a sample of 4-nonylphenol

[0125] 100 mg of 4-nonylphenol (manufactured by GL Science Inc.) was weighed out on an electronic balance with a 10 ml volumetric flask, and dissolved in ethanol to obtain a final volume of exactly 10 ml. Transfer 3ml of this solution with a pipette to another volumetric flask (50ml) and then dilute to 50ml exactly with ethanol.

[0126] The above-mentioned bisphenol B was used as an internal standard. (c) Determination of the absorption of 4-nonylphenol by microorganisms and the residual amount of 4-nonylphenol

[0127] 0.2 ml of the ethanol solution of 4-nonylphenol obtained in (b) was added to a glass test tube containing 3.8 ml of the supernatant of live or heat-treated bacteria as described in (a) above. The mixture was stirred well and then left to stand in a 37°C water bath. After 60 minutes, the cells were pelleted by centrifugation and 0.95 ml of the super...

Embodiment 1

[0172] Statistical analysis was performed on the obtained data according to Dunnett's multivariate control method. Example 1 Lactobacillus casei (Lactobacillus casei) YIT 9029 absorbs bisphenol A (1)

[0173] Live bacteria or heat-treated bacteria of Lactobacillus casei (Lactobacillus casei) YIT 9029 were obtained according to the sample preparation method described in (1) (a) above. Using these samples, the relationship between the concentration of the microorganisms and the amount of bisphenol A was measured. Samples of live or heat-treated bacteria of Lactobacillus casei YIT9029 at different concentrations (0, 0.625, 1.25, 2.5, 5 and 10 g / l) were prepared. 40 µg of bisphenol A was added to these samples and reacted, and then the amount of bisphenol A remaining in the supernatant was analyzed by gas chromatography, thereby determining the amount of absorbed bisphenol A. The result is shown in Figure 1. (result)

[0174] As shown in Figure 1, the amount of bisphenol A ads...

Embodiment 2

[0175] Therefore, it can be determined that foods and beverages prepared using these microorganisms do not necessarily need to contain live bacteria, but that these foods and beverages can be prepared under a wide range of conditions such as temperature, pH, and the like. Example 2 Lactobacillus casei (Lactobacillus casei) YIT 9029 absorbs bisphenol A (2)

[0176] Using living bacteria of the microorganism Lactobacillus casei (Lactobacillus casei) YIT 9029, the relationship between the bacterial concentration, the amount of absorbed bisphenol A, and the amount of residual bisphenol A was investigated. Live bacterial samples of Lactobacillus casei (Lactobacillus casei) YIT 9029 were prepared at different concentrations (0, 0.625, 1.25, 2.5, 5 and 10 g / l). To these samples was added 20 μg of bisphenol A. After the reaction, according to the GC / MS method and the gas chromatography method described in the above-mentioned (1) (c) and (1) (e), and according to the calculation formu...

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Abstract

A mayonnaise-like food, being an edible emulsified matter prepared by mixing and emulsifying soybean milk or bean curd, vinegar, seasoning, spice, emulsifier, and vegetable oil, in which the soybean milk is a concentrated soybean milk at Brix concentration of 20 to 40, or the bean curd is a concentrated bean curd prepared by coagulating a concentrated soybean milk at Brix concentration of 15 or more by use of a coagulant. Since concentrated soybean milk or concentrated bean curd is used, peculiar greenstuff smell and acridity of soybean can be suppressed, and a mayonnaise-like food having rich flavor and smooth texture can be obtained.

Description

technical field [0001] The present invention relates to an absorbent for endocrine-disrupting chemicals capable of absorbing and clearing endocrine-disrupting chemical substances ingested orally, and more particularly to an absorbent for endocrine-disrupting chemicals and a product containing the absorbent Food, the absorbent can not only absorb endocrine-disrupting chemical substances in the intestinal cavity of humans or animals, thereby inhibiting the absorption of such substances in the body, but also accelerate the excretion of such chemical substances absorbed in the body. Background technique [0002] For a long time, people have applied organotins to the bottom of boats to prevent the adsorption of crustaceans. Endocrine-disrupting chemicals (or environmental hormones) have been considered to be It is a substance that can cause serious social problems. The endocrine system of organisms is a very important system. It regulates the evolution of individual organisms, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L29/00A61K35/74A61P39/02C12N1/21
CPCA23L1/0158A23L1/3014A23L1/0345A23L1/00A23L2/02A23L1/0026A23L2/52A23P10/28A23L5/28A23L29/065A23L33/135A61P39/02A61K35/74
Inventor 大石宪司泽田治司横井稚惠吉田康人渡边常一
Owner YAKULT HONSHA KK
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