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Use of mica in preparing medicine

A kind of mica, application technology, applied in the direction of drug combination, aluminum/calcium/magnesium active ingredients, digestive system, etc., to achieve the effect of abundant quantity, tight arrangement and uniform dyeing

Inactive Publication Date: 2003-07-30
HANGZHOU ZHEDA GASTROENTEROPATHY DIAGNOSE TECH RES DEV
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Problems solved by technology

Literature search shows that there is no report on the treatment of chronic atrophic gastritis with mica at home and abroad

Method used

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  • Use of mica in preparing medicine
  • Use of mica in preparing medicine
  • Use of mica in preparing medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1 and ：        5000g      2000g    (PH＝6)      200g to       200L：①1％：2kg，200L，，②1％：5g，500ml，③：10g，10ml④，1％PH to 6.0⑤， to Embodiment 2

[0070] The mica raw material is washed, dried, calcined, cooled, ground, and passed through a 1000-mesh sieve. Embodiment one: the prescription and process prescription of mica gel are as follows: mica 5000g carbomer 2000g sodium bicarbonate appropriate amount (PH=6) chlorocresol 200g add water to 200L process is as follows: 1. allocate 1% carbomer gel matrix : Take 2kg of carbomer, add 200L of water, stir to dissolve, and form a transparent and uniform gel matrix ②Preparation of 1% sodium bicarbonate solution: Take 5g of sodium bicarbonate, add 500ml of water, stir and dissolve ③Preparation of chlorocresol solution: Weigh 10g Add 10ml of water to dissolve chlorocresol. 4. Get the carbomer matrix and adjust the pH to 6.0 with 1% sodium bicarbonate solution. 5. Add mica while stirring, and stir until it becomes a uniform gel. Example 2: Prescription and process of mica powder The prescription is as follows: mica 3000g microcrystalline cellulose 1000g sorbic acid 40g aspartame 3...

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Abstract

The present invention relates to a new use of mica in preparing medicine for atrophic gastritis. By means of duplication of rat model of chronic atrophic gastritis, are observed the morphopathological, nuclear proliferation antigen and epidermal growth factor effects of mica and its positive reference medicine sucralfate. The results show that mica can reduce gastric mucosa inflammation cell infiltration and glandulose atrophy, increase the positive expression of glandulose nuclear proliferation antigen and raise the expression level of blood serum epidermal growth factor. That is to say, mica has relatively high rat chronic atrophic gastritis treating effect and certain chronic atrophic gastritis preventing and treating effect.

Description

[0001] Involved areas [0002] The present invention relates to the use of mica, in particular to the use in the pharmaceutical field. Background technique [0003] Mica is a silicate mineral drug. The main hydrous potassium aluminum silicate, its chemical molecular structure is KAl 2 Si 3 Al 10 (OH) 2 . The main components are silica and alumina. [0004] The main function of mica is mainly to invigorate the spleen, and it is mainly used for the treatment of weakness, weakness of qi, dizziness, cold malaria, chronic dysentery, chronic enteritis, externally used for carbuncle sores, gold wound bleeding embolism. However, mica is mostly used as an active ingredient in traditional Chinese medicine compound preparations for clinical use, and mica single preparations are rarely used. In the book "Mineral Drug Atlas of Traditional Chinese Medicine", there are more detailed pharmacological studies: after entering the stomach, it can...

Claims

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Application Information

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IPC IPC(8): A61K33/06A61P1/04
Inventor 姚健敏王良静王海云许妙范敏华
Owner HANGZHOU ZHEDA GASTROENTEROPATHY DIAGNOSE TECH RES DEV
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