Hypoglycemic medicine contg. slime bacteria sporocarp and preparing process thereof

A bacterium seed and hypoglycemic technology, which is applied in the field of hypoglycemic drugs containing myxobacteria fruiting bodies or their extracts and its preparation, can solve problems that have not been reported in domestic and foreign technical documents or patents, and achieve good economic benefits and The effect of market prospect, low cost and simple production method

Inactive Publication Date: 2003-08-13
SHANDONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Drugs made from fruiting bodies of myxobacteria or extracts of fruiting bodies as main raw materials have been proved to have the effect of lowering blood sugar through animal experiments. Literature and patent searches show that they are prepared from fruiting bodies of myxobacteria or their extracts Hypoglycemic drugs have not been reported in domestic and foreign technical literature or patents

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] A hypoglycemic oral liquid containing myxobacteria sporocarp water extract and a preparation method thereof. Specific steps are as follows:

[0049] (1) Preparation and treatment of myxobacteria sporocarps: take the cultured and prepared myxobacteria sporocarps for fresh use directly, or dry the myxobacteria sporocarps and make powder for later use.

[0050] (2) Preparation of raw materials: main materials and auxiliary materials are prepared according to the following weight percentages: 70% of myxobacteria fruiting body, 30% of Ganoderma lucidum spore powder.

[0051] (3) Preparation of water extract: the raw material prepared in (2) was eluted with hot water at 80° C., the eluate was concentrated by evaporation under reduced pressure, and dried at 80° C. to obtain a water extract.

[0052] (4) Preparation of oral liquid: weigh the water extract of (3), add 3.5% of sucrose, caramel 2%, honey 4%, American ginseng essence (or other fruity essence) 0.5% by weight, Diss...

Embodiment 2

[0054] An oral hypoglycemic granule containing an organic solvent extract of myxobacteria sporocarp and a preparation method thereof. Specific steps are as follows:

[0055] (1) Preparation and treatment of myxobacteria sporocarps: take the cultured and prepared myxobacteria sporocarps for fresh use directly, or dry the myxobacteria sporocarps and make powder for later use.

[0056] (2) Preparation of raw materials: main materials and auxiliary materials are prepared according to the following weight percentages: 90% of myxobacteria fruiting body, 10% of Ganoderma lucidum spore powder.

[0057] (3) Preparation of methanol extract: the raw material prepared in (2) was extracted with methanol, a polar organic solvent, and the extract was evaporated and concentrated under reduced pressure at 60° C., and the organic solvent was removed to obtain a methanol extract.

[0058] (4) Preparation of dichloromethane extract: the sample after (3) methanol leaching is extracted with non-po...

Embodiment 3

[0061] An oral hypoglycemic granule medicine containing the organic solvent extract of myxobacteria sporocarp and a preparation method thereof. Specific steps are as follows:

[0062] (1) Preparation and treatment of myxobacteria sporocarps: take the cultured and prepared myxobacteria sporocarps for fresh use directly, or dry the myxobacteria sporocarps and make powder for later use.

[0063] (2) Selecting and preparing myxobacteria sporocarps at a ratio of 100% by weight.

[0064] (3) Preparation of ethanol extract: the raw material prepared in (2) was extracted with polar organic solvent ethanol, the extract was evaporated and concentrated under reduced pressure at 60° C., and the organic solvent was removed to prepare ethanol extract.

[0065] (4) Preparation of petroleum ether extract: extract the sample extracted by (3) ethanol with petroleum ether, a non-polar organic solvent, and the extract is evaporated and concentrated under reduced pressure at 40°C, and the organic...

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PUM

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Abstract

A hypoglycemic medicine is prepared from myxobacterial sporophore or its extract and conventional auxiliaries through proportional mixing. Its advantages are high effect on reducing blood sugar and treating diabetes, and no toxic by-effect.

Description

(1) Technical field [0001] The invention relates to the field of pharmaceutical products and their preparation, in particular to a drug capable of lowering blood sugar and treating diabetes and a preparation method thereof, in particular to a drug for lowering blood sugar containing myxobacteria fruiting body or its extract and its preparation method. Preparation. (2) Background technology [0002] In China, the health of 50 million people is threatened by diabetes, and the annual cost of treating diabetes is as high as 170 billion yuan. What is even more worrying is that many Chinese have not checked their blood sugar levels, and have not taken effective control measures. Therefore, experts estimate that there are still a large number of hidden diabetes and impaired glucose tolerance patients in China. Therefore, the prevention and treatment of diabetes has become an urgent task. With the improvement of material living standards and awareness of medical care, the demand f...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P3/10
Inventor 李越中扈锡涛韩冠君胡玮刘新利夏志洁
Owner SHANDONG UNIV
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