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Oral drip-pill of sarcandra glaber and preparing process

A preparation process and technology of dropping pills, which is applied in the field of oral drop pills and preparation of sargassum, can solve the problems that the efficacy is not fully exerted, and achieve the effects of increased bioavailability, small side effects, and high efficacy

Inactive Publication Date: 2004-02-11
许军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no oral drop pill made of sargassum medicinal material after extraction, and its effectiveness has not been fully exerted.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Add 3125g of Sargassum to decoct 3 times with water (5 times, 3 times, 3 times respectively) for 1 hour each time, combine the decoction, filter, concentrate the filtrate to dryness, add polyethylene glycol 6000 300g, stearin 50g of sodium bicarbonate and 10g of poloxamer, after heating, melting and mixing, drop into the condensation of simethicone oil at a rate of 60 drops per minute at 60°C-80°C, after forming, take it out, remove the condensing agent, Inspect the amount of ingredients, pass, pack, and get the finished product. Every 1000 servings of sarcocarp oral drop pills contains 3125g of sarcocarp extract.

Embodiment 2

[0016] Take 3125g of sarcophagus and add water to decoct 3 times (the amount of water is 5 times, 3 times, 3 times respectively) for 1 hour each time, combine the decoction, filter, precipitate with ethanol, recover the ethanol, concentrate to dryness, and dry soak After the paste, add 200g of polyethylene glycol 6000 and 50g of sodium stearate, heat, melt and mix well, then drop it into the condensation of simethicone oil at a rate of 40 drops per minute at 60°C-80°C, after forming , take it out, remove the condensing agent, inspect the component quantity, pass it, pack it, and get the finished product. Every 1000 servings of sarcocarp oral drop pills contains 3125g of sarcocarp extract.

Embodiment 3

[0018] Take 3125g of Zhongjiefeng and add water to decoct 3 times (the amount of water is 5 times, 3 times, 3 times respectively) for 1 hour each time, combine the decoction, filter, concentrate the filtrate to dryness, add 500g of polyoxyethylene monostearate , glyceryl monostearate 60g, poloxamer 15g, heating and melting, after mixing, drop into the camellia oil at a rate of 70 drops per minute at 60°C-80°C, after forming, take it out, remove As for the condensing agent, the component quantity is inspected, qualified, packaged, and the finished product is obtained. Every 1000 servings of sarcocarp oral drop pills contains 3125g of sarcocarp extract.

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PUM

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Abstract

The present invention discloses oral drip pill of sarcandra glaber and its preparation process. The oral drip pill has sarcandra glaber extractive as active components and proper amount of matrix. The matrix is polyglycol-6000, polyglycol-4000, polyethylene glycol monostearate, sodium stearate, glyceryl glutin, poloxamer, stearic acid, glyceryl monostearate, insect wax or their mixture. The preparation process includes decoction of sarcandra glaber, concentration, mixing the filtrate with alcohol via stirring, setting, concentration to obtain dry extractum, mixing with matrix while heatingto 60-100 deg.c, dripping into condensating agent, taking out, inspection and packing, with the condensating agent being dimethyl silicon oil, liquid paraffin, tea oil, rape seed oil, gasoline or their mixture.

Description

technical field [0001] The invention relates to an oral drop pill, in particular to an oral drop pill for treating acute and chronic throat and oral cavity inflammation, acute upper respiratory infection, bronchitis and acute pneumonia and a preparation method thereof. Background technique [0002] Zhongjiefeng is a plant of Chrysanthemum orchidaceae, also known as grass coral, Jiujiecha, Yagushan and so on. Respiratory tract infection, bronchitis, acute pneumonia and common cold. [0003] Zhongjiefeng Oral Dropping Pill refers to the preparation made by extracting, concentrating and drying the medicinal material of Zhongjiefeng, heating, melting and mixing it with related substrates, dropping it into an immiscible condensing agent, shrinking and condensing. Its main features are that the extraction rate of sargassum medicinal ingredients is high, the bioavailability is increased, the drug effect is rapidly exerted, the side effects are small, it is convenient to take and t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61P1/02A61P11/00
Inventor 许军彭红
Owner 许军
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