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Dripping pills preparation and its preparing process

A technology of drop pills and preparations, which is applied in the field of traditional Chinese medicine drop pill preparations and its preparation, can solve the problems of inconvenient taking, bad taste, and limited efficacy of Tankejing buccal tablets and Tankejing powder, etc., and achieve easy control, Easy to take, fast dissolution effect

Inactive Publication Date: 2004-11-17
CHIA TAI TIANQING PHARMA GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But Tankejing lozenges and Tankejing powder are inconvenient to take, the dosage is large, the taste is not good, and the efficacy is limited

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Grind 28.4g Platycodon grandiflorum and 1.2g Polygala into coarse powder, impregnate with 117ml and 7ml 70% ethanol respectively for 24 hours, then percolate at a percolation speed of 3ml / min·kg, collect the percolation liquid, and set aside.

[0048] Grind 29.5g of licorice into a coarse powder, add 295ml of water to decoct twice for 2 hours each time, filter, combine the filtrate, concentrate to 1g of crude drug / ml, add ethanol to make the alcohol content reach 60%, stand for 4 hours, Filter and set aside. Crush 5.9g of bitter almonds into coarse particles, immediately immerse in boiling water for 30 minutes, add 48ml of water to decoct twice, use the same preparation method as licorice, and use the filtrate for later use. The two are combined with the above-mentioned percolation liquid, the ethanol is recovered and concentrated to 0.65g crude drug / ml, and the concentrated liquid is used for future use.

[0049] Crush 7.2g gallnuts, pass through a 120-mesh sieve, and...

Embodiment 2

[0051]Add 26.2g of caffeine into the spare concentrated solution of Example 1, heat to dissolve completely, then add the melted auxiliary material polyethylene glycol 4000 141.4g, heat in a water bath and stir evenly, add 7.2g gallnut powder, mix well and add borneol 43g, heated in a water bath until the borneol is completely melted, transferred to the liquid storage tank, sealed and kept warm at 90~95°C, adjusted the valve, selected a dripper with a weight of 20mg per pill, and dripped 6°C liquid paraffin from top to bottom In the cooling liquid, the dripping speed is 35 pills / minute. After the dropping pills are formed, take them out, absorb the cooling liquid on the surface, and dry them.

Embodiment 3

[0053] Add 26.2g of caffeine into the concentrated solution of Example 1, heat to dissolve completely, then add in 141.4g of molten auxiliary material gelatin, heat and stir in a water bath, add 7.2g gallnut powder, add borneol 43g after mixing, and heat in a water bath to The borneol is completely melted, transferred to the liquid storage tank, sealed and kept warm at 95°C to adjust the valve, select a dripper with a weight of 60mg per pill, and drop it into the vegetable oil cooling liquid at 10°C from top to bottom, at a dripping speed of 40 pills / minute. After the dropping pills are formed, take them out, absorb the cooling liquid on the surface, and dry them.

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PUM

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Abstract

The invention provides a traditional Chinese medicinal cough relieving drop pill preparation and method for preparing it, wherein the preparation comprises caffeine, boneol, licorice root, root of ballon flower, polygala root, bitter apricot seed, and gallnut.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine dripping pill preparation and a preparation method thereof. The preparation is prepared from traditional Chinese medicine prescriptions such as caffeine, borneol, licorice, bellflower, polygala, bitter almond, gallnut and the like. Background technique: [0002] Tankejing lozenges and Tankejing powder have been used in clinical practice for many years. They are compound preparations of traditional Chinese medicine and western medicine. It has the effects of clearing the orifice and smoothing the Qi, reducing inflammation and relieving cough, and promoting expectoration. It is clinically used for acute and chronic bronchitis, chest tightness, pharyngitis, emphysema, etc. treatment effect. [0003] Chronic bronchitis, referred to as chronic bronchitis, is a common and frequently-occurring disease that seriously endangers people's health, and is a common disease of middle-aged and elderly people in...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K35/64A61P11/00
Inventor 张锡昌张来芳张琼光周浩陈维
Owner CHIA TAI TIANQING PHARMA GRP CO LTD