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Chinese medicine particle for treating chronic hyperplasia of prostate

A technology of prostatic hyperplasia and traditional Chinese medicine granules, which is applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, can solve the problems of low occupation rate of traditional Chinese medicines and inconvenience for patients to use, achieve anti-inflammatory effect, prevent the progress of inflammation, The effect of reducing inflammatory cell infiltration

Inactive Publication Date: 2005-03-02
张正生
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] A search of domestic patents for BPH therapeutic drugs reveals that many patents are still in a relatively extensive stage in terms of dosage forms, which is inconvenient for patients to use. This is one of the reasons for the low share of traditional Chinese medicine in the BPH therapeutic drug market

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Weigh Zelan 400g, Radix Paeoniae Rubra 600g, Piper Cucumber 267g Trillium 267g according to the ratio

[0033] Saponaria thorn 333g black medicine 267g Polygonatum 267g

[0034] The above Qiwei and Radix Paeoniae Rubra are crushed into coarse particles, added 70% ethanol to reflux and extracted twice, each time for 1 hour, filtered, the filtrate is decompressed to recover ethanol, concentrated to a clear paste with a relative density of 1.28 (60°C), and set aside; , Sanleng, black medicine, Piper Cubebium soaked in 12 times of water for 0.5 hours, distilled and extracted the volatile oil for 4 hours, collected the volatile oil, dissolved in 1ml of absolute ethanol for every 1ml of the volatile oil, and slowly added it to the saturated aqueous solution of β-cyclodextrin (the volatile oil : β-cyclodextrin = 1:6), stirred at 40°C for 2 hours, refrigerated overnight, filtered with suction, dried at 40°C, sieved, set aside, and the distilled aqueous solution was collected in...

Embodiment 2

[0036] Weigh by proportion

[0037] Zelan 570g, Chishao 900g, Piper Cucumber 400g, Triangular 380g

[0038] Saponaria thorn 500g black medicine 420g Polygonatum 400g

[0039] The preparation method is the same as that in Example 1, and 1500 g of granules are made, which are sub-packed in aluminum film bags (1 g per bag) to obtain a Chinese medicine granule for treating chronic benign prostatic hyperplasia of the present invention.

Embodiment 3

[0041] Weigh by proportion

[0042] Zelan 360g, Chishao 552g, Piper Cucumber 240g Triangular 240g

[0043] Saponaria thorn 280g black medicine 240g Polygonatum 240g

[0044] The preparation method is the same as in Example 1, and 1000 g of granules are made, which are sub-packed in aluminum film bags (1 g per bag), to obtain a Chinese medicine granule for treating chronic benign prostatic hyperplasia of the present invention.

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PUM

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Abstract

The Chinese medicine granule for treating chronic hyperplasia of prostate is prepared with Chinese medicinal materials including eupatorium, red peony root, cubeb litsea fruit, burreed rhizome, lindera root, honey locust spine and sealwort. The preparation process includes crushing and alcohol extracting red peony root to obtain extractum; water extracting eupatorium, cubeb litsea fruit, burreed rhizome and lindera root to obtain volatile oil; clathrating the volatile oil with beta-cyclodextrin; twice water extracting the medicine residue and honey locust spine and sealwort and concentration to obtain water extracted concentrate; merging the concentrate and extractum, decompression drying; adding the clathrate and supplementary material; and pelletizing and drying. Research shows that the granule has functions of promoting blood circulation to disperse blood clots, etc. and has obvious curative effect on hyperplasia of prostate and chronic prostatitis.

Description

Technical field [0001] The preparation of the invention relates to a traditional Chinese medicine for treating chronic prostatic hyperplasia, which belongs to the technical field of traditional Chinese medicine. Background technique [0002] The prostate is an important organ of the male genitourinary system and the largest accessory gonad in males. It is located at the bladder outlet at the bottom of the bladder and surrounds the beginning of the male urethra. It is about the size of a chestnut, about 3 to 4 cm in diameter, and weighs about 20 grams. The prostate is composed of acini, and there are several small tubes that communicate with the urethra. The main function is to produce prostatic fluid, which can directly enter the urethra and be discharged. In human semen, prostatic fluid accounts for about 30%. Due to the special structure of the prostate, the course of the disease is lengthy and recurrent, so it is difficult to cure it. Western medicine has not fully cla...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/16A61P13/08
Inventor 张正生
Owner 张正生