Matrine pellicle and its preparation process

A ginseng film agent and ginseng film technology, applied in the directions of antifungal agent, sheet delivery, sexual diseases, etc., can solve the problem of no matrine product coming out, limited use of lotion, and many fillers and auxiliaries. and other problems, to achieve the effect of stable main drug properties, light weight, and less use of auxiliary materials

Inactive Publication Date: 2005-03-16
贵阳高新瑞得科技开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The efficacy of these agents is unknown, but the use of lotion is limited; effervescent tablets and gels contain more fillers and auxiliaries, and the production cost is higher
The gynecological

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Example 1: Weigh 50g of polyvinyl alcohol, add 200ml of water, soak for 0 hours, put it in a water bath at 20°C to dissolve it, take 25mg of matrine and mix it with the aqueous solution, remove air bubbles, apply it to form a film, and dry it After 0.5 hour, 1000 film products were prepared.

Embodiment 2

[0024] Example 2: Weigh 150g of sodium carboxymethylcellulose, add 400ml of water, soak for 0.5 hours, place it in a water bath at 50°C to dissolve it, take 50mg of matrine and dissolve it with a mixed solution of 50ml of water and ethanol, and then mix the two The solution was mixed and stirred evenly, 0.2 g of sodium sulfite was added, mixed evenly, air bubbles were removed, and after coating to form a film, it was dried for 1 hour to obtain 1000 film products.

Embodiment 3

[0025] Example 3: Weigh 300g of starch, add 500ml of water, soak for 3 hours, put it in a water bath at 60°C to dissolve it, take 60mg of matrine and dissolve it with a mixed solution of 300ml of water and ethanol, then mix the two solutions and stir evenly , add 1.5 g of sodium bisulfite, mix well, remove air bubbles, apply and form a film, and dry for 1.5 hours to obtain 1000 film products.

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PUM

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Abstract

Disclosed is a matrine pellicle and its preparation process, wherein the pellicle comprises matrine as the active constituent, and added anti-oxidant and fill forming material. The matrine pellicle preparing process consists of, steeping the film forming material with water, dissolving by water-bath, dissolving the matrine with the mixed solution of water and ethanol, mixing with the aqueous solution of the film forming material, adding anti-oxidant simultaneously, mixing, removing air bubbles, coating into film and drying.

Description

technical field [0001] The invention relates to pharmaceutical preparations, in particular to a matrine film for treating women's vaginitis and a preparation method thereof. Background technique [0002] Non-specific vaginitis is a common and frequently-occurring disease in women, usually caused by vaginal mold, trichomonas, and bacterial infections, often presenting symptoms such as profuse leukorrhea, yellowish smell, itchy vulva, bitter mouth, and chest tightness. Bring great pain and inconvenience to patient. For vaginitis, both Chinese and Western medicine have some treatment methods, and Chinese medicine also has proven prescriptions for treatment. Among them, there are already "Baofukang Suppositories" and "Fuyankang Suppositories" on the market. Sometimes there is a foreign body feeling, the volume is large, and the use is greatly affected by environmental conditions, especially temperature and humidity. [0003] In recent years, the use of...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K31/4375A61P15/02A61P31/04A61P31/10A61P33/02
Inventor 李向东卢顺林何斌余昌昀
Owner 贵阳高新瑞得科技开发有限公司
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