Loxoprofen sodium sustained release preparation

A technology of loxoprofen sodium and sustained-release preparations, applied in the field of medicine, can solve the problems of inability to show curative effect, peak-to-valley phenomenon, side effects and the like
CN1628648AInactive Publication Date: 2005-06-22FUDAN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
FUDAN UNIV
Publication Date
2005-06-22
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides a Loxoprofen sodium sustained release preparation, wherein the preparation comprises Loxiprofen sodium as active component and pharmaceutically acceptable carrier, the components include (1) skeleton type, membrane control type, or penetration pump type tablet or capsule, (2) microcapsule, small pill, microballoon, emulsion, and slow release preparation, (3) space or time delay type slow release preparation.
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Description

technical field

[0001] The invention belongs to the technical field of medicine, and in particular relates to a composition containing loxoprofen sodium, more specifically, the invention relates to a slow-release preparation of loxoprofen sodium. Background technique

[0002] Loxoprofen sodium is a phenylpropionic acid non-steroidal analgesic anti-inflammatory drug, the chemical name is 2-[4-(2-oxocyclopentane-1-ylmethyl)phenyl]propionate sodium dihydrate , the molecular formula is C 15 h 17 NaO 3 2H 2 O, the structural formula is as follows:

[0003]

[0004] Loxoprofen sodium is white crystal or crystalline powder. It is very soluble in water or methanol, easily soluble in ethanol, and almost insoluble in ether. Loxoprofen sodium has excellent analgesic and anti-inflammatory effects, characterized by strong analgesic effect, anti-inflammatory and antipyretic effects similar to other similar drugs, and weak activity on chronic inflammation. Clinically, it can be w...

Claims

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