5 results about "Sodium loxoprofen" patented technology

The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to a loxoprofen sodium preparation and a preparation method thereof. The loxoprofen sodium preparation is composed of a loxoprofen sodium tablet and a tablet outer layer coating, the outer layer coating comprises the following raw materials: L-glutamine, carboxylated chitosan and a coloring agent, the L-glutamine accounts for 24-26% of the mass of the outer layer coating, the carboxylated chitosan accounts for 17-30% of the mass of the outer layer coating, and the coloring agent accounts for 1-2% of the mass of the outer layer coating. The preparation method mainly comprises the following steps: firstly, preparing loxoprofen sodium tablets by a wet granulation process, then preparing a coating solution, and finally, carrying out film coating on the tablets by using the coating solution to obtain the loxoprofen sodium preparation. According to the loxoprofen sodium preparation and the preparation method thereof provided by the invention, the process is simple and convenient, the coating is stable, the release is controllable, the prepared preparation is suitable for being taken by various patient groups, and the medication safety and compliance are further improved while the curative effect is guaranteed.

1. The name of the design product: medicine packaging box (losofil sodium gel paste). 2. The use of the design product: the design is used for the outer packaging of losofil sodium gel paste. 3. The design points of the design product: the combination of shape, pattern and color. 4. The picture or photo that best indicates the design points: perspective view. 5. The design claimed contains color.

1. Name of the designed product: packing box (sodium loxoprofen gel plaster). 2. Use of the designed product: for packing products. 3. Design points of the designed product: combination of shape and pattern. 4. Picture or photo best indicating the design points: perspective view.

The present invention addresses the problem of providing a patch that has excellent skin permeability and good adhesiveness. [Solution] A patch provided with a support and an adhesive layer laminated on the support, the adhesive layer containing loxoprofen sodium hydrate, hydrated silica, polyisobutylene, glycerol ester of hydrogenated rosin, a styrene-isoprene-styrene block copolymer, and phosphoric acid. Based on the total mass of the adhesive layer, the content of the silicon dioxide hydrate is preferably 0.3%-1% by mass, the content of the polyisobutene is preferably 5%-15% by mass, the content of the glycerol ester of the hydrogenated rosin is preferably 10%-20% by mass, the content of the styrene-isoprene-styrene block copolymer is preferably 17%-27.5% by mass, and the content of the phosphoric acid is preferably 0.1%-1.5% by mass.

The invention relates to a loxoprofen sodium patch and a preparation method thereof. The loxoprofen sodium patch comprises a backing layer, a drug-containing matrix layer and a stripping layer, the stripping layer is in contact with the drug-containing substrate layer, and the backing layer covers the drug-containing substrate layer; the drug-containing matrix layer comprises loxoprofen sodium, a penetration enhancer and an acrylate pressure-sensitive adhesive, and the tail end of the acrylate pressure-sensitive adhesive only contains a carboxyl group. The loxoprofen sodium patch is stable in performance, simple in component and excellent in adhesion performance, and has a good transdermal release effect.