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Xuening dripping pill having hemostatic function and its preparing method

A technology for hemostasis and dripping pills, which is used in medical preparations containing active ingredients, pill delivery, blood diseases, etc. It is beneficial to labor protection and environmental protection, improving bioavailability, and no dust pollution.

Inactive Publication Date: 2005-10-19
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
Granules also have relatively low drug content, which is inconvenient to take and other deficiencies
[0007] In addition, conventional oral dosage forms, such as tablets, capsules, granules (infusions), etc., due to the granulation process in the preparation process, will generate relatively large dust pollution, which will cause health problems to the staff to a certain extent. harm, and also cause some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0028] Now with several groups of specific examples, the preparation method of Xuening dripping pills of the present invention is further described:

[0029] Group 1: Tests with a single matrix

[0030] 1. Raw materials: according to the preparation method 1, first prepare the dry powder of the medicinal extract for later use;

[0031] 2. Substrate: polyethylene glycol (1000、2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc.;

[0032] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0033] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain Xuening Dropping Pills of different specifications.

[0034] [test results]

[0035] Test 1: In order to observe the difference in quality of the Xuening Dropping Pills prepared when the ratio of drug extracts to different...

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PUM

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Abstract

The present invention relates to a kind of medicine composition, Xuening dripping pill, with functions of arresting bleeding and for auxiliary treatment of hemophilia, thromboctopenia, purpura, nosebleeding, etc. The present invention has high bioavailability, fast medicine release, fast acting, high effective content, taking convenience and low cost, and the production process has no pollution. The Xuening dripping pill is prepared with peanut coat as one kind of Chinese medicinal material and medicine carrier as matrix.

Description

technical field [0001] The invention relates to a pharmaceutical composition with hemostatic effect, which is used for auxiliary treatment of diseases such as hemophilia, thrombocytopenia, purpura, epistaxis, bleeding gums, etc., especially relates to the preparation of traditional Chinese medicine peanut shells for the above diseases A pharmaceutical composition oral preparation. Background technique [0002] According to the ministerial drug standard WS 3 - Xuening granule prepared by the preparation method given in B-0927-91 is a kind of oral medicine that has hemostatic effect and is used for adjuvant treatment of hemophilia, thrombocytopenia, purpura, epistaxis, gingival bleeding and other diseases Granules, clinically proven, have definite curative effects, and are commonly used medicines for clinical and family treatment of such diseases. [0003] The following is the drug standard WS 3 - Formula and process and brief description given in B-0927-91: [0004] Prepa...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P7/04
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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