Prepn of composite film of nanometer ordered Ca-P compound and collagen

A technology of ordered structure and composite film layer, applied in the direction of electrolytic inorganic material coating, etc., can solve the problems that the mechanical properties of ceramic materials are difficult to meet the requirements, the biocompatibility and biological activity of metal materials are poor, and the traditional materials are difficult to meet the use conditions and other problems
CN1740400AInactive Publication Date: 2006-03-01XIAMEN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
XIAMEN UNIV
Publication Date
2006-03-01
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to electrochemical deposition process for preparing nanometer ordered CaP / collagen coating on the surface of medical metal product. The present invention provides one kind biological material with bone-like structure and homogeneous chemical property prepared in mild condition, and the material has greatly raised biocompatibility and bioactivity and may be applied clinically. The preparation process includes the following steps: pre-treatment of the substrate, and cathode electrochemical deposition of the substrate inside the calcium phosphate deposition solution with collagen dispersing liquid and pH 3-6 in current density of 0.1-1.0 mA / sq cm and at 50-100 deg.c for 10-30 min.
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Description

technical field

[0001] The invention relates to a new method for controllably preparing nanometer ordered structure calcium phosphate compound (CaP) / collagen composite coating on the surface of medical metal by electrochemical deposition. Background technique

[0002] Natural bone is a multi-level complex system ingeniously combined with inorganic components and organic components, and it is basically constructed by calcium phosphate salts and collagen fibers. These two basic components have very different mechanical properties: the calcium-phosphorus mineral is hard and brittle, and the glue principle is soft and tough. The two components in natural bone are combined with each other and have excellent mechanical properties (P. Fratzl, H.S. Gupta, E.P. Paschalis et al.. J. Mater. Chem., 2004, 14: 2115). Traditional bone replacement materials, such as metals, ceramics, and medical polymers, are often used to restore some bone functions. When medical metal materials and bioc...

Claims

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