Alloy as magnesium element as matrix and its use as bone-fracture internal fixer

Abstract

This invention discloses an alloy with Mg element as the matrix and the use as a fixer for fractures. Content of the composition and weight percentage is: Mg: 90-99.7%, other metals: 0.3~10%, which can be the fixer for fractures since it can provide suitable starting strength and degradation speed matched to knitting.

Description

technical field [0001] The invention relates to an alloy with magnesium element as matrix and the application of the alloy as a fracture internal fixator. technical background [0002] The fracture (fracture of bone) mentioned in the present invention is usually a traumatic fracture. Bone has a strong ability to regenerate, and traumatic fractures after good reduction can generally heal completely within 3-4 months. The proliferation of osteoblasts in the outer and inner membrane and the generation of new bone are the basis of fracture healing. After the fracture, the bone heals completely through the process of hematoma formation, fibrous and bony callus formation, and callus reconstruction, so that the bone structure and function return to normal. [0003] The biomechanical research on bone growth and bone healing shows that the various stresses borne inside the bone determine the shape and structure of the bone to a certain extent, and also determine the arrangement str...

AI Technical Summary

Problems solved by technology

Its advantages lie in high strength, convenient shaping, and easy storage, etc., but there are also significant defects: (1) The mechanical compatibility of metal internal fixation is poor, that is, the mechanical compatibility between the metal material and bone tissue does not match, resulting in stress uneven distribution

(2) The histocompatibility of metal internal fixation is poor, mainly due to the corrosion of the metal, and the released metal ions can cause adverse reactions such as allergic reactions and aseptic inflammation in the body

(3) A second operation is required to remove the internal fixation

[0010] However, due to the lack of mechanical strength of the internal fixation materials based on absorbable polymer materials, the scope of application is also very limited, and can only be used for cortical bone fixation with low mechanical performance requirements; The degradation method of the material in the body is bulk degradation, that is, it is degraded simultaneously from the surface of the material to the inside of the material. Since the internal degradation products cannot diffuse, the internal degradation will be accelerated, and the degradation products will cause local inflammation and other biological reactions. Conducive to the later healing of bone tissue

In addition, the strength performance of traditional bioabsorbable internal fixators is not compatible with the fracture healing speed