DNA chip for traditional Chinese medicine anti tumour mechanism rapid analysis and its method

A DNA chip and mechanism of action technology, applied in the field of bioengineering, can solve problems such as the inability to analyze large gene expression changes
CN1766121AInactive Publication Date: 2006-05-03哈尔滨基太生物芯片开发有限责任公司
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
哈尔滨基太生物芯片开发有限责任公司
Publication Date
2006-05-03
Estimated Expiration
Not applicable · inactive patent

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Abstract

The DNA chip with opposite method to express analyze the action mechanism of anti-tumor Chinese traditional medicine overcomes the shortcoming that it can not analyze a mass of gene expression variety. Wherein, the chip relates to apoptosis, periodic control, and drug transformation metabolism. The analysis method comprises: with objective drug as tool drug and tumor cell strain as cell model, using said Chinese drug to act on the model; screening the sensitive cell line opposite to tool drug; detecting drug-acted gene with gene expression spectrum chip; stating and classifying gene with bioinformation science; according to drug label gene and change low of special tumor gene, validating the mechanism on molecular cell level.
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Description

technical field

[0001] The invention belongs to the technical field of bioengineering, and in particular relates to a DNA chip capable of rapidly analyzing the action mechanism of anti-tumor traditional Chinese medicines and a technology thereof. Background technique

[0002] Malignant tumor is a major disease that endangers human health, and has become the second leading cause of death in various diseases after cardiovascular disease. In my country, about 900,000 cancer patients die every year, and the number of deaths has been increasing year by year in recent years. Therefore, countries all over the world have invested heavily in research and development of anti-tumor drugs. It is obvious that the market prospect of antineoplastic drugs is promising. Although dozens of chemotherapeutic or adjuvant antineoplastic drugs can be used in clinical treatment so far, most of these drugs can only alleviate the disease, but cannot achieve the purpose of cure. Especially most com...

Claims

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