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High throughput biological indicator reader

A biological indicator and reader technology, applied in sanitary equipment for toilets, biochemical equipment and methods, and microorganism measurement/inspection, etc. The effect of high throughput and convenient storage

Inactive Publication Date: 2006-05-03
3M INNOVATIVE PROPERTIES CO
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  • Abstract
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AI Technical Summary

Problems solved by technology

Sterilization cycles are not effective if the culture product is grown in a biological indicator

Method used

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  • High throughput biological indicator reader
  • High throughput biological indicator reader
  • High throughput biological indicator reader

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0028] figure 1 is a block diagram illustrating a system 10 for analysis of biological indicators. Such as figure 1 As shown in , system 10 may include biological indicator reader 12 , biological indicator incubator 14 , sterilizer 16 and computer 18 . Reader 12 processes reference biological indicator 20 to obtain an initial baseline fluorescence measurement for later evaluation of biological indicator 22 to detect proper sterilization. In general, system 10 supports high volume and high throughput in reading out biological indicators 22 to detect fluorescence and thereby determine the efficacy of a sterilization cycle.

[0029]System 10 may be used in healthcare facilities to monitor sterilization efficacy over large sterilization loads. Alternatively, system 10 may be used to estimate the sterilization efficacy of equipment, instruments, medical devices, implants, and other items before such items are commercially released from a manufacturing facility, among other thing...

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PUM

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Abstract

A high capacity reader detects fluorescence emitted by a biological indicator to determine the efficacy of a sterilization cycle. The reader permits a large number of biological indicators to be read in rapid succession. For example, the biological indicators may be pre-incubated in a separate, high capacity incubator and then placed in a high capacity reader for fluorescence detection. The reader makes a positive or negative growth determination based on a single fluorescence threshold comparison for each pre-incubated biological indicator. The single fluorescence threshold comparison involves comparison of measured fluorescence to a baseline fluorescence of a reference biological indicator. The reader acquires the baseline fluorescence from the reference biological indicator, and thereafter uses the baseline fluorescence as the threshold for subsequent biological indicators processed by the reader. In addition, the reader may generate output for storage, processing and display of biological indicator results.

Description

technical field [0001] The present invention relates to techniques for determining the efficacy of a sterilization cycle, and in particular techniques for reading fluorescence from biological sterilization indicators in order to determine the efficacy of a sterilization cycle. Background technique [0002] Sterilization generally refers to the process of eliminating all bacteria and other living organisms from the surfaces of instruments, medical devices, implants, and other items used in sterile surgical procedures. Traditional thermal sterilization processes use pressurized steam. Low temperature chemical sterilization uses ethylene oxide, hydrogen peroxide, hydrogen peroxide / hydrogen plasma, or peracetic acid in liquid or vapor form as the sterilant, as well as gamma irradiation and electron beam sterilization. [0003] During each sterilization cycle, the sterilizer is designed to kill all viable organisms within the chamber. To achieve this goal, health care personnel...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L2/28C12Q1/02C12Q1/22
CPCC12Q1/22A61L2/28
Inventor 布赖恩·S·别胡恩兰迪·L·弗拉斯基
Owner 3M INNOVATIVE PROPERTIES CO
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