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Helicid dripping pills and its prepn. method

A technology of tofu fructose and pectin dripping pills is applied in the directions of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, which can solve problems such as single variety and so on.

Inactive Publication Date: 2006-06-14
YUNNAN INST OF MATERIA MEDICA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But at present, the dosage form of tofu glucoside is only tablets, and the variety is relatively single.

Method used

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  • Helicid dripping pills and its prepn. method

Examples

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Comparison scheme
Effect test

Embodiment 1

[0015] 12 g of tofu glucoside and 8 g of xylitol were pulverized respectively, passed through a 100-mesh sieve, and then fully mixed with 5 g of micropowdered silica gel. According to the ratio of 1:5 to the weight ratio of the medicine, polyethylene glycol 400060g is placed in the container, heated and melted in a water bath, and slowly added the sieved raw material drug tofu glucoside and xylitol while stirring, fully After mixing, the mixture is poured into the insulation tank of the dropper, and the dropping temperature is kept at 75-90°C. Select a suitable dripper and dropping speed, drop the mixture into methyl silicone oil to form pellets, solidify, wash off the coolant on the surface of the pellets with petroleum ether (60-90°C), and dry at room temperature to obtain tofu Fruit Glycerin Dropping Pills.

Embodiment 2

[0017] Grind 12g of tofu glucoside, 3.84g of sucrose, and 0.48g of citric acid, pass through a 100-mesh sieve, and mix with 8g of starch evenly. Put polyethylene glycol 6000 36g in a container at a ratio of 1:3 by weight to the drug, heat and melt in a water bath, and slowly add sieved raw drug tofu glucoside, sucrose, and citric acid while stirring , After fully mixing, pour the mixture into the insulation tank of the dripping device, and keep the dripping temperature at 100-115°C. Select a suitable dripper and dropping speed, drop the mixture into methyl silicone oil to form pellets, solidify, wash off the coolant on the surface of the pellets with petroleum ether (60-90°C), and dry at room temperature to obtain tofu Fruit Glycerin Dropping Pills.

Embodiment 3

[0019] 12 g of tofu glucoside, 1.8 g of aspartame, and 1.8 g of citric acid were pulverized respectively, passed through a 100-mesh sieve, and then mixed evenly with 7 g of micropowdered silica gel. Put 48g of polyoxyethylene stearate in a container at a ratio of 1:4 by weight to the drug, heat and melt in a water bath, and slowly add the sieved crude drug Shenshuaiguo, A After the spartame and citric acid are fully mixed, pour the mixture into the insulation tank of the dropper, and keep the dropping temperature at 70-90°C. Select a suitable dripper and dropping speed, drop the mixture into liquid paraffin to form pellets, solidify, filter, wash off the coolant on the surface of the pellets with petroleum ether (60-90°C), and dry at room temperature to obtain tofu fruit Glycoside dripping pills.

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PUM

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Abstract

A dripping pill of helicidum is proportionally prepared from helicidum, polyethandiol, flavouring and disperser. It has high curative effect, stability and solubility.

Description

technical field [0001] The invention relates to a bean curd glucoside dripping pill and a preparation method thereof, belonging to the technical field of pharmaceutical preparations. Background technique [0002] Tofu glucoside is an active ingredient extracted from the fruit of the radish tree of the mountain dragon eye plant, which has strong analgesic, sedative, and hypnotic effects. It is suitable for relieving headache, dizziness and sleep disturbance of neurosis, and assisting the treatment of primary headache. Insomnia is very serious in western developed countries, 30% to 35% of adults in the United States suffer from insomnia, and 30% in France. It is also a very common problem in my country. Epidemiological investigations show that the incidence rate of insomnia adults is 30-35%, especially in the majority with women and the elderly. There are as many as 700 million adults in my country, and 120 million elderly people. With the rapid development of society, the a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7028A61K9/20A61P25/04A61P25/20
Inventor 周莹王京昆孙媛字刚段丽萍李东明
Owner YUNNAN INST OF MATERIA MEDICA
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