Capsule type digestive tract medicine releasing and sampling device

Abstract

The sample type digestive tract medicine releasing and sampling device includes a shell to form sealed cavity; an inwards non-return valve communicated with the inside of the shell in the front end of the shell; a magnetic switch, a power source, a power source managing and controlling unit, a driving unit, a sealing layer and a rubber piston inside the shell; and an outer trigger. After the triggering signal the outer trigger sends is received and treated by the signal control unit, the driving unit relieves the stored mechanical energy based on the command to drive the piston, the stored medicine is exhausted through an outwards non-return valve to the digestive tract, and liquid enters the liquid storing bin through the opened inwards non-return valve. After the piston reaches to the top of the shell, the stroke ends, two valves are closed automatically to separate the collected liquid inside the liquid storing bin from outside. The medicine releasing and sampling device has high reliability, low power consumption, long stand-by time and simple structure.

Description

technical field [0001] The invention relates to a swallowable digestive tract miniature device, in particular to a capsule type digestive tract drug release and sampling device, which can be used to simultaneously realize drug release and liquid sampling in the digestive tract of a human body or an animal. Background technique [0002] The fixed-point release of drugs and liquid sampling in the digestive tract are widely used, especially in the study of the absorption characteristics of drugs in different parts of the digestive tract, and the study of the metabolic status and related biochemical characteristics of the digestive tract are of great value. It has laid a solid foundation for the development of new drugs and provided an auxiliary means for the detection of gastrointestinal diseases. Therefore, the research on capsule drug release and sampling devices for gastrointestinal tract has naturally become a hot spot. [0003] U.S. Patent N...

AI Technical Summary

Problems solved by technology

This device has the following problems: First, the release of the drug depends on the size of the small hole pierced by the needle in the drug storage balloon in the middle of the drug storage chamber and the internal pressure of the balloon. If the internal pressure of the balloon containing the drug is not large enough, the drug will be released The speed is slow; the drug is viscous and may not be released; secondly, because the channel for the drug to be released from the device is a small hole on the wall of the shell, and the balloon containing the drug will block these small holes due to its good deformability In addition, even if the balloon can shrink rapidly after being punctured, its contraction force only guarantees the release of the drug into the drug storage chamber, and the release of the drug from the drug storage chamber depends on the leakage of the small holes, which will be absorbed by the digestive tract substances. Sealed, the drug cannot leak out through the small hole without proper external pressure

This device has the following problems: first, the biggest shortcoming of this device is that the structure is complicated

Since the device uses the movement of the piston to generate a partial vacuum for sampling, the piston must discharge gas when it moves to one end, so a vent hole is specially designed in the device, and the vent hole is blocked with a detachable plug. When sampling, the piston uses air pressure to squeeze out the plug. If the plug cannot be disengaged during the operation, sampling cannot be performed and the reliability is reduced.

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