Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application and prepn. process of shiyacha total flavone

The technology of Shiya tea and total flavonoids is applied in the field of medicine, which can solve the problems of high price, many adverse reactions, etc., and achieve the effects of convenient taking, less toxic and side effects, and good taste.

Inactive Publication Date: 2006-09-20
ZHEJIANG UNIV
View PDF0 Cites 16 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] In recent years, drugs for the treatment of hyperlipidemia have developed rapidly, but they have the disadvantages of many adverse reactions or high prices

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application and prepn. process of shiyacha total flavone
  • Application and prepn. process of shiyacha total flavone

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 2

[0060] Implementation example two: the influence of Shiya tea total flavonoids on liver lipid level and AST, ALT of hyperlipidemic rats: 1. The test method is the same as implementation example 1, and the rat serum is taken to measure AST and ALT values, and the IFCC method is adopted; The SOD and MDA values ​​were measured with an ultraviolet spectrophotometer, and the reagents were purchased from Nanjing Jiancheng Bioengineering Co., Ltd.; the TC and TG levels of liver homogenate were measured by enzymatic method. At the same time, the liver tissue was taken, routinely fixed for pathology, embedded in paraffin, sectioned at 5um, and stained with HE.

[0061] 2. Results:

[0062] 2.1 Effects of SYC on rat liver function and liver lipids (results are shown in Table 2)

[0063] The liver TC, TG and serum AST and ALT of the rats in the model group were significantly increased, which was significant compared with the normal control group (P<0.05), suggesting that fatty degenerat...

Embodiment 3

[0075] Implementation example 3: Effect of total flavonoids of Shiya tea on whole blood viscosity and platelet aggregation rate of hyperlipidemic rats:

[0076] 1. The test method is carried out according to Example 1. Take 1ml of fresh blood from rats, anticoagulate with 0.3ml of 125U / ml heparin, and measure the viscosity of whole blood on the Prism LBY-N6B coagulation analyzer. Take 3ml of fresh blood from rats, anticoagulate with 3.8% citric acid at a ratio of 1:9, take poor and rich plasma, and measure the platelet aggregation rate on the Prism LBY-NJ4 platelet aggregation analyzer.

[0077] 2. Results:

[0078] Compared with rats in the normal group, the platelet aggregation rate in the model group increased (P0.05), but can reduce the platelet aggregation rate (P<0.05). Compared with Xuezhikang, the total flavonoids of Shiya tea is better in changing the hemorheological indexes of rats with hyperlipidemia.

[0079]

group

dosage

whole blood vi...

Embodiment 4

[0084] Preparation scheme 1 of the total flavonoids of Shiya tea: take Shiya tea leaves, add ethanol, reflux extraction, recover and concentrate, precipitate with water, take supernatant, recover and concentrate, and spray dry to obtain dry powder;

[0085] Take the above dry powder, add distilled water to dissolve to obtain a solution, extract the solution with petroleum ether, discard the petroleum ether layer, and then extract the water layer with ethyl acetate until the color of the water layer disappears, combine the ethyl acetate extracts, and recover ethyl acetate under reduced pressure Esters were vacuum-dried to obtain a dry paste. That is the total flavonoids of Shiya tea. The dry paste is pulverized, mixed with auxiliary materials, granulated, packed into capsules, packed in blisters and packaged outside. The process flow is attached figure 2 .

[0086] Preparation scheme two of total flavonoids of Shiya tea: the above scheme one, use methanol extraction instead...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

An application of Shiyachaí»s flavone in preparing the medicine and functional health-care food for preventing and treating hyperlipemia and the diseases caused by hyperlipemia of people and mammal and the additive of food or forage for regulating blood fat is disclosed. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to the use of total flavonoids of Shiya tea and a preparation method thereof. Background technique [0002] Guangxi is located in the subtropical zone and is one of the southernmost provinces of the motherland. There are many species in the mountainous areas of Guangxi, and many of them have been widely developed and utilized with the discovery and understanding of people and the advancement of science and technology. And it has become a pollution-free and healthy drink that people love and favor. Shiya tea is a kind of natural and wild precious famous tea produced exclusively in Guangxi. Due to the unique taste of this tea, it is slightly bitter when you drink it, and then there is a long-lasting, mellow slightly sweet taste accompanied by the unique fragrance of this plant. The smell is deeply loved by people in Southeast Asian countries. However, due to the limited wild resour...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048A61K31/37A61P3/06A61P9/10A23K1/16A23L1/03A23K10/30A23L29/00
Inventor 吴理茂李连达
Owner ZHEJIANG UNIV
Features
  • Generate Ideas
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com