Composition with function of relieving cough and calming asthma and preparing method

A technology for relieving cough and relieving asthma and composition, which is applied in the field of compositions with relieving cough and relieving asthma, and can solve the problems of general curative effect, poor M receptor selectivity, and large side effects of hormones

Active Publication Date: 2006-10-25
LUNAN HOPE PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 1 Glucocorticoids Glucocorticoids are still the most effective anti-inflammatory drugs at present. The essence of asthma is chronic non-specific airway inflammation. Hormones have effective anti-inflammatory effects, which can inhibit delayed allergic reactions and reduce airway sensitivity , but the side effects of hormones are large. There are many reports that excessive dosage of inhaled glucocorticoids will still produce hormone-like side effects, and may cause drug dependence or drug resistance. Clinically, steroid-resistant asthma and steroid-dependent asthma have appeared
[0005] 2 Theophylline Theophylline drugs have been used in the treatment of bronchial asthma and chronic obstructive pulmonary disease for decades. Theophylline can inhibit phosphodiesterase and increase the levels of cyclic adenosine monophosphate and cyclic guanosine monophosphate , diastolic bronchial smooth muscle also has: anti-inflammatory effect, immunoregulatory effect, antagonizing adenosine receptor, inducing B cell apoptosis, increasing diaphragmatic muscle tension, reducing diaphragmatic muscle fatigue, etc. Small, easy to cause adverse reactions such as poisoning
[0006] 3. β 2 - Agonist beta 2 - Receptor agonists have been promoted as the first choice for the treatment of bronchial asthma, but some research results show that the standard treatment of B2 receptor agonists alone can make asthma worse
[0007] 4. Anticholinergic M-receptor blockers have a long history in the treatment of bronchial asthma. They can inhibit the release of acetylcholine from the motor nerve of the vagus nerve in the bronchial smooth muscle and play an antiasthmatic effect. However, due to poor selectivity to M receptors, it can cause dry mouth, Thick sputum, central nervous system excitement and other systemic side effects
At present, there are Linggui Kechuanning Capsules, Kechuan Pills, Miracle Loquat Zhike Granules, Jizhi Syrup and other products on the market, which have the effect of relieving cough and relieving asthma, but the curative effect is mediocre

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0152] Coltsfoot flower 3 parts Bellflower 15 parts Lily 20 parts Mulberry 9 parts Chuan Bei 9 parts Baiqian 9 parts Agrimony 6 parts

[0153] 6 parts of Peucedanum, 6 parts of tangerine peel, 20 parts of melon, 15 parts of licorice, 15 parts of aster, 15 parts of Ophiopogon japonicus, 9 parts of mulberry leaves

[0154] 6 parts of Schisandra, 6 parts of Baibu, 9 parts of almond, 15 parts of Zhebei, 6 parts of Shegan, 9 parts of Bletilla striata, 50 parts of Chinese yam

[0155] Add 5 times of water to the above medicines, soak for 0.5 hours, decoct for 1 hour, filter, add 5 times of water, and decoct for 1 hour; combine the decoction liquid, filter, and concentrate under reduced pressure until the medicinal materials: water is about 1:1 , adjust the alcohol to 40%, cool down for 48 hours, filter, concentrate under reduced pressure to form an extract, add dextrin and powdered sugar to make granules, dry, make granules, and pack to obtain granules.

Embodiment 2

[0157] Coltsfoot flower 15 parts Bellflower 4 parts Lily 20 parts Mulberry 9 parts Chuanbei 9 parts Baiqian 9 parts Agrimony 6 parts

[0158] 6 parts of Peucedanum, 6 parts of tangerine peel, 20 parts of melon, 15 parts of licorice, 15 parts of aster, 15 parts of Ophiopogon japonicus, 9 parts of mulberry leaves

[0159] 6 parts of Schisandra, 6 parts of Baibu, 9 parts of almond, 15 parts of Zhebei, 6 parts of Shegan, 9 parts of Bletilla striata, 50 parts of Chinese yam

[0160] Add 10 times water to the above drug, soak for 3 hours, and decoct for 1 hour; combine the decoction liquid, filter, concentrate under reduced pressure until the medicinal material: water is about 2:1, adjust the alcohol to 85%, and refrigerate for 12 hours. Filtrate, concentrate under reduced pressure to form an extract and dry, add appropriate amount of dextrin and powdered sugar to make soft materials, granulate with a granulator, dry, and pack to obtain granules.

Embodiment 3

[0162] Coltsfoot flower 15 parts Bellflower 15 parts Lily 4 parts Mulberry 9 parts Chuanbei 9 parts Baiqian 9 parts Agrimony 6 parts

[0163] 6 parts of Peucedanum, 6 parts of tangerine peel, 20 parts of melon, 15 parts of licorice, 15 parts of aster, 15 parts of Ophiopogon japonicus, 9 parts of mulberry leaves

[0164] 6 parts of Schisandra, 6 parts of Baibu, 9 parts of almond, 15 parts of Zhebei, 6 parts of Shegan, 9 parts of Bletilla striata, 50 parts of Chinese yam

[0165] Add 8 times of water to the above medicine, soak for 1 hour, decoct for 3 hours, filter, add 10 times of water to the dregs of the medicine, and decoct for 2 hours; combine the decoction, filter, and concentrate under reduced pressure to contain 3g of medicinal materials per ml , add ethanol to 50% alcohol content, cool down for 48 hours, filter, concentrate under reduced pressure to form an extract, dry, add donkey-hide gelatin powder and appropriate amount of starch to make granules, fill capsules, an...

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PUM

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Abstract

The present invention discloses a Chinese medicine composition with action of relieving cough and asthma. Said Chinese medicine composition contains 21 Chinese medicinal materials of tussilago flower, platycodon root, lily bulb, peucedanum root, tangerine peel, Chinese yam, schisandra berry, licorice and others.

Description

technical field [0001] The invention relates to a composition with the functions of relieving cough and relieving asthma, in particular to a composition with functions of relieving cough and relieving asthma which is made from Chinese herbal medicine. Background technique [0002] Cough and asthma is one of the most common chronic diseases in the world. At present, there are nearly 200 million patients in the world. At present, the annual cost of asthma treatment in the United States has exceeded 6 billion US dollars. The prevalence rate in my country is close to 1%, and the number of patients is more than 10 million. . It is a disease that seriously endangers people's physical and mental health, weakens their ability to work, and reduces their quality of life, and it is difficult to be cured. Asthma has become a serious public nuisance problem. Therefore, actively preventing and treating asthma, reducing the morbidity and mortality of asthma, and effectively controlling and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61P11/06A61P11/14
Inventor 赵志全
Owner LUNAN HOPE PHARM CO LTD
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