Zinc sulfate freeze-dried preparation for injection

A technology of freeze-dried preparations and lipoic acid, which is applied in the direction of freeze-dried transportation, medical preparations containing active ingredients, anti-toxic agents, etc., can solve the problems of lipoic acid instability, limited production and use, etc., and achieve high stability and meet The desired effect of clinical treatment
CN1853626AInactive Publication Date: 2006-11-01SHANGHAI INST OF PHARMA IND CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHANGHAI INST OF PHARMA IND CO LTD
Publication Date
2006-11-01
Estimated Expiration
Not applicable · inactive patent
Patent Text Reader

Abstract

A freeze-dried powder injection of thioctic acid contains proprotionally the thioctic acid, antioxidizing agent and pH regulator. Its advantages are high curative effect and high stability.
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Description

technical field

[0001] The invention relates to a lipoic acid preparation, in particular to a lipoic acid freeze-dried preparation for injection. Background technique

[0002] In 1951, lipoic acid (Thioctic Acid; Lipoic Acid; α-Lipoic Acid) was the first natural product isolated from pig liver by Reed, which is the oxidative decarboxylation of α-ketoglutarate in the pyruvate and tricarboxylic acid cycle Coenzyme factor of the reaction. In the past, the understanding of it only stayed in the role of energy metabolism. Modern research shows that it has anti-oxidation effect, prevents and treats many diseases, and is known as a universal antioxidant.

[0003] This product has the following characteristics: (1) It is easy to transform in cells. Experiments have proved that lipoic acid (oxidized form) can be reduced to dihydrolipoic acid (reduced form) by lipoamide dehydrogenase in mitochondria after most mammalian cells ingest lipoic acid. And released to the outside of the ce...

Claims

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