Composition for treating eye's fungal and bacterial infection

Abstract

The present invention discloses one kind of composition for treating eye's fungal and bacterrial infection. The composition has at least one of mercury preservatives, including merthiolate, merphenyl nitrate, merphenyl nitrate alkali, phenylmercuric acetate, phenylmercuric borate, etc as well as their salts and derivatives as the main active component; supplementary material including antioxidant, pH regulator and osmotic pressure regulator; and water as the solvent and carrier. The composition may be prepared into different preparation forms for treating eye's fungal and bacterrial infection.

Description

Technical field: [0001] The invention relates to an ophthalmic medicine, in particular to a composition for treating fungal and bacterial infection of the eye for treating fungal keratitis or bacterial keratoconjunctivitis. Background technique: [0002] Fungal keratitis is a common eye disease with a high rate of blindness, and drug therapy is the main treatment for fungal keratitis. At present, there are only two commercial drugs available for ocular fungal infection in my country: natamycin eye drops and fluconazole eye drops. Natamycin eye drops produced by Alcon Company of the United States is currently the only ophthalmic antifungal preparation approved by the U.S. FDA, and it has a better early effect for fungal infections. However, because the drug is insoluble in water, its suspension has poor corneal penetration, so it is not effective for deep corneal infection, especially for those with hypopyon. Fluconazole is currently the only domestically produced commercia...

AI Technical Summary

Problems solved by technology

[0003] In order to solve the problem that there are few types of ophthalmic drugs for the treatment of fungal keratitis and the single function, the purpose of the present invention is to provide a kind of ophthalmic drug which has both high-efficiency anti-fungal and anti-bacterial activities and improves the therapeutic effect of fungal and bacterial keratoconjunctivitis. Composition for treating fungal and bacterial infections of the eye