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Dry powder of gelatinous polysaccharide of aloe, producing method and preparation

A technology of aloe vera gel polysaccharide and aloe vera gel, which is applied in the direction of pill delivery, capsule delivery, powder delivery, etc. It can solve the problems of limited application, instability, and easy discoloration, so as to reduce the cost of storage and production and broaden the scope of use , The effect of simple production process

Inactive Publication Date: 2010-05-12
BAOLINGYANGTAIHE BIOTECH HANGZHOU
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Because aloe contains a large amount of active substances, these substances are relatively active, so the stability of aloe products on the market is not yet perfect
Due to the defects of instability, easy oxidation and easy discoloration of aloe gelatin, its application in pharmaceuticals is greatly limited.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0027] The preparation method of aloe curdlan dry powder of the present invention, it comprises the following steps:

[0028] First, the purchased aloe is cleaned and manually screened to remove impurities;

[0029] Second, the stabilization of aloe vera gel, including: ① color protection stabilization: add color protection solution immediately after aloe juice is squeezed; ② inactivation of enzymes: quickly heat aloe vera juice to boiling, and inactivate the enzymes in aloe vera; ③ stabilization: Add antioxidants and stabilizers;

[0030] Third, the enzymatic hydrolysis and flocculation of aloe vera gel, including: ① Enzymatic reaction: hydrolyze with compound enzymes such as pectinase, amylase protease and polygalactosidase, and hydrolyze the insoluble or poorly water-soluble ones. ②Heat treatment: rapid heating, in the sudden high and low temperature changes, the protein and other colloidal substances in aloe vera are denatured and precipitated, copper and protein can be r...

Embodiment 1

[0044] The aloe used in the aloe gelatin dry powder produced by the above process, if its lactic acid and acetic acid cannot be detected within 3 hours after harvesting, the content of L-malic acid is: 817.8-3427.8mg / L. Other production methods remain unchanged.

[0045] The level of malic acid can only evaluate the strictness of the production process of aloe products. Aloe vera leaves are fresh, the production process is strictly controlled, and the degree of microbial contamination is small, so the peak of malic acid is high. On the contrary, for heavily polluted aloe products, the peak of malic acid gradually decreases, and even can be completely digested by microorganisms, and malic acid cannot be detected.

Embodiment 2

[0047] The ratio of the aloe gelatin to the hydroxypropyl β-cyclodextrin by weight is: aloe: hydroxypropyl β-cyclodextrin=5:0.5. Dissolve hydroxypropyl β-cyclodextrin in hot water at 60°C and stir to dissolve it completely. Add the aloe curdlan and stir to form a homogeneous solution. Grinding with a colloid mill, the grinding time is more than 20 minutes, so that the aloe gelatin and hydroxypropyl β-cyclodextrin are fully included. Then freeze-dry at a temperature of -40°C and a vacuum of 100 Pa. The dried block was crushed into the particle size required by the preparation, and sieved to obtain a 100:1 dry powder of aloe curdlan (1 part of the dry powder contained 100 parts of aloe raw materials).

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Abstract

This invention discloses a method for producing dry powder of aloe gel polysaccharide and its preparations. The dry powder of aloe gel polysaccharide is composed of aloe gel polysaccharide and hydroxypropyl-beta-cyclodextrin at a weight ratio of 5 : (0-5), preferential 5 : (0-1), and optimal 5 : (0-0.5). The method comprises: washing aloe, screening, controlling the freshness, pressing to obtain juice, stabilizing, enzymolyzing, flocculating, decolorizing, filtering, concentrating, examining, preparing raw materials, encapsulating by hydroxypropyl-beta-cyclodextrin, drying, pulverizing, packaging, examining and storing. The preparations are produced by adding dry powder of aloe gel polysaccharide into drinkable water to obtain 5% solution, and can exist in the forms of tablets, capsules, granules and oral liquid. The method has such advantages as simple process, high aloe stability, and low storage.

Description

technical field [0001] The invention relates to an aloe product, in particular to an aloe curdlan dry powder, a preparation method thereof and a preparation prepared therefrom. Background technique [0002] Aloe vera is an ancient and miraculous plant. With the change of the times, the miraculous functions of aloe vera quickly attracted the attention of scientists from all over the world. After biochemical analysis, it was found that the polysaccharide-gel contained in aloe vera is the most important active ingredient in aloe vera. substance. These substances have the functions of antibacterial, bactericidal, decomposing toxins, eliminating inflammation and promoting wound healing. [0003] In addition, aloe vera gel also has the effects of helping digestion and promoting metabolism, and has pharmacological effects such as laxative, invigorating the stomach, stimulating the menstrual flow, detoxifying, anti-tumor, and anti-ulcer. It has good or certain curative effect on i...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C08L5/00C08L5/16A61K31/715A61K9/28A61K9/48A61K9/14
Inventor 沈文忠赵志良虞英民
Owner BAOLINGYANGTAIHE BIOTECH HANGZHOU