Lysine-chitosan resin and preparation method thereof

Abstract

The present invention is lysine-chitosan resin and its preparation process, and relates to chitosan modifying technology with lysine. The lysine-chitosan resin consists of chitosan, glutaraldehyde and lysine simply. The preparation process of lysine-chitosan resin includes the first reverse suspending process to prepare chitosan microsphere, the subsequent cross-linking with glutaraldehyde as cross-linking agent to prepare cross-linked chitosan resin and final modification with lysine to prepare the lysine-chitosan resin. The lysine-chitosan resin has homogeneous granularity, rich pores, high acid and alkali resistance and excellent effect of adsorbing acid radical anion, amino acid and protein, is regenerable, and may be used widely in medicine, food, cosmetics, water treatment, chemical and other fields.

Description

1. Technical Field

[0001] The invention belongs to the field of reactive polymers, and particularly relates to a lysine modified chitosan resin and a preparation method thereof. 2. Technical background

[0002] With the improvement of people's quality of life, production and consumption have become more environmentally friendly, and there is a need for further development of natural renewable resources. Chitosan is a deacetylated product of chitin. It has excellent functional properties and unique molecular structure, such as abundant sources, non-toxic, renewable, easy to chemically modify, and biocompatibility. It has an exchange effect on weakly basic anions. , Has a good effect on many heavy metal ions, therefore, chitosan is widely used in medicine, food, cosmetics, water treatment, chemical industry, agriculture and other fields. However, most of the natural chitosan is in powder form, with a small specific surface area, and is easily dissolved in acidic media and lost, whi...

Examples

Embodiment 1

[0022] The components and mass percentage of a lysine-chitosan resin are:

[0023] Chitosan 42%

[0024] Glutaraldehyde 22%

[0025] Lysine 35%

[0026] The specific method steps of a lysine-chitosan resin preparation method are as follows:

[0027] (1) Preparation of chitosan microspheres

[0028] Weigh each component in proportion for use, that is, the mass percentages of chitosan, glutaraldehyde and lysine are 42%, 22% and 35% respectively. First dissolve chitosan in 0.1% dilute hydrochloric acid (HCl), stir and dissolve at room temperature to obtain a chitosan acid sol with a mass fraction of 1%, and then place it in liquid paraffin with the same volume as 0.1% hydrochloric acid In the container, under stirring, slowly add chitosan acid sol, continue stirring for 20 minutes, so that the chitosan sol droplets are uniformly dispersed into microspheres, and the chitosan microsphere system is prepared.

[0029] (2) Preparation of cross-linked chitosan resin

[0030] The chitosan m...

Embodiment 2

[0034] The components and mass percentage of a lysine-chitosan resin are:

[0035] Chitosan 43%

[0036] Glutaraldehyde 20%

[0037] Lysine 36%

[0038] The specific method steps of a lysine-chitosan resin preparation method are as follows:

[0039] (1) Preparation of chitosan microspheres

[0040] Weigh each component in proportion for use, that is, the mass percentages of chitosan, glutaraldehyde and lysine are 43%, 20% and 36% respectively. First dissolve chitosan in 0.2% dilute hydrochloric acid (HCl), stir and dissolve at room temperature to prepare an acidic chitosan sol with a mass fraction of 1.5%, and then fill it with liquid paraffin equal in volume to 0.2% hydrochloric acid In the container, under stirring, slowly add the chitosan acid sol, and continue stirring for 25 minutes to uniformly disperse the chitosan sol droplets into microspheres to prepare a chitosan microsphere system.

[0041] (2) Preparation of cross-linked chitosan resin

[0042] Heat the chitosan micros...

Embodiment 3

[0045] Example 3: The components and mass percentage ratio of a lysine-chitosan resin are:

[0046] Chitosan 44%

[0047] Glutaraldehyde 21%

[0048] Lysine 34%

[0049] The specific method steps of a lysine-chitosan resin preparation method are as follows:

[0050] (1) Preparation of chitosan microspheres

[0051] Weigh each component in proportion for use, that is, the mass percentages of chitosan, glutaraldehyde and lysine are 44%, 21% and 34% respectively. First dissolve chitosan in 0.3% dilute hydrochloric acid (HCl), stir and dissolve at room temperature to obtain a chitosan acid sol with a mass fraction of 2%, and then place it in liquid paraffin with the same volume as 0.3% hydrochloric acid In the container, under stirring, slowly add the chitosan acid sol, continue stirring for 30 minutes, so that the chitosan sol droplets are uniformly dispersed into microspheres, and the chitosan microsphere system is prepared.

[0052] (2) Preparation of cross-linked chitosan resin

...

1. Technical Field

[0001] The invention belongs to the field of reactive polymers, and particularly relates to a lysine modified chitosan resin and a preparation method thereof. 2. Technical background

[0002] With the improvement of people's quality of life, production and consumption have become more environmentally friendly, and there is a need for further development of natural renewable resources. Chitosan is a deacetylated product of chitin. It has excellent functional properties and unique molecular structure, such as abundant sources, non-toxic, renewable, easy to chemically modify, and biocompatibility. It has an exchange effect on weakly basic anions. , Has a good effect on many heavy metal ions, therefore, chitosan is widely used in medicine, food, cosmetics, water treatment, chemical industry, agriculture and other fields. However, most of the natural chitosan is in powder form, with a small specific surface area, and is easily dissolved in acidic media and lost, whi...

Examples

Embodiment 1

[0022] The components and mass percentage of a lysine-chitosan resin are:

[0023] Chitosan 42%

[0024] Glutaraldehyde 22%

[0025] Lysine 35%

[0026] The specific method steps of a lysine-chitosan resin preparation method are as follows:

[0027] (1) Preparation of chitosan microspheres

[0028] Weigh each component in proportion for use, that is, the mass percentages of chitosan, glutaraldehyde and lysine are 42%, 22% and 35% respectively. First dissolve chitosan in 0.1% dilute hydrochloric acid (HCl), stir and dissolve at room temperature to obtain a chitosan acid sol with a mass fraction of 1%, and then place it in liquid paraffin with the same volume as 0.1% hydrochloric acid In the container, under stirring, slowly add chitosan acid sol, continue stirring for 20 minutes, so that the chitosan sol droplets are uniformly dispersed into microspheres, and the chitosan microsphere system is prepared.

[0029] (2) Preparation of cross-linked chitosan resin

[0030] The chitosan m...

Embodiment 2

[0034] The components and mass percentage of a lysine-chitosan resin are:

[0035] Chitosan 43%

[0036] Glutaraldehyde 20%

[0037] Lysine 36%

[0038] The specific method steps of a lysine-chitosan resin preparation method are as follows:

[0039] (1) Preparation of chitosan microspheres

[0040] Weigh each component in proportion for use, that is, the mass percentages of chitosan, glutaraldehyde and lysine are 43%, 20% and 36% respectively. First dissolve chitosan in 0.2% dilute hydrochloric acid (HCl), stir and dissolve at room temperature to prepare an acidic chitosan sol with a mass fraction of 1.5%, and then fill it with liquid paraffin equal in volume to 0.2% hydrochloric acid In the container, under stirring, slowly add the chitosan acid sol, and continue stirring for 25 minutes to uniformly disperse the chitosan sol droplets into microspheres to prepare a chitosan microsphere system.

[0041] (2) Preparation of cross-linked chitosan resin

[0042] Heat the chitosan micros...

Embodiment 3

[0045] Example 3: The components and mass percentage ratio of a lysine-chitosan resin are:

[0046] Chitosan 44%

[0047] Glutaraldehyde 21%

[0048] Lysine 34%

[0049] The specific method steps of a lysine-chitosan resin preparation method are as follows:

[0050] (1) Preparation of chitosan microspheres

[0051] Weigh each component in proportion for use, that is, the mass percentages of chitosan, glutaraldehyde and lysine are 44%, 21% and 34% respectively. First dissolve chitosan in 0.3% dilute hydrochloric acid (HCl), stir and dissolve at room temperature to obtain a chitosan acid sol with a mass fraction of 2%, and then place it in liquid paraffin with the same volume as 0.3% hydrochloric acid In the container, under stirring, slowly add the chitosan acid sol, continue stirring for 30 minutes, so that the chitosan sol droplets are uniformly dispersed into microspheres, and the chitosan microsphere system is prepared.

[0052] (2) Preparation of cross-linked chitosan resin

...

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